scholarly journals Sarcomatoid Lesions of Head and Neck Region: A Diagnostic Dilemma

Author(s):  
Dipankar Samaddar ◽  
Ananjan Chatterjee ◽  
. Abhinandan ◽  
Deepak Kumar ◽  
. Akriti

One challenging feature of head and neck pathology is that a dizzying array of sarcomatoid lesions occurs here ranging all the way from reactive to malignant and very aggressive. This makes accurate diagnosis critical. These lesions are quite diverse with great clinical and biological heterogeneity. Some are malignant while many others are benign or simply reactive in nature. For example; at mucosal sites, a well known lesion is spindle cell carcinoma (SpCC), which are overtly malignant, and the differential diagnosis then includes a number of different malignant spindle cell lesions. However, there are several benign or even non-neoplastic lesions that can sometimes be difficult to discern from SpCC, e.g. Nodular fasciitis, Proliferative myositis, Cellular schwannoma, Benign fibrous histiocytoma, Carcino sarcoma, Sarcomatoid melanoma. Fracture callus, etc. Aim of Study: There is a diagnostic challenge to the oral pathologists to differentiate dizzying array of sarcoma like lesions from other similar microscopic simulates ranging all the way from reactive to malignant and very aggressive. This article aims to review the sarcomatoid lesions of the head and neck region with emphasis on differential diagnosis histologically and immunohistochemicaly.

2018 ◽  
Vol 111 (8) ◽  
pp. 557-563
Author(s):  
Hiyori Takahashi ◽  
Kenichi Watanabe ◽  
Masayuki Shirakura ◽  
Yohei Honkura ◽  
Daisuke Yamauchi ◽  
...  

2021 ◽  
Vol 156 (0) ◽  
pp. 61-65
Author(s):  
Yuki Yamaguchi ◽  
Seiji Hosokawa ◽  
Junya Kita ◽  
Daiki Mochizuki ◽  
Atushi Imai ◽  
...  

2010 ◽  
Vol 40 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Phuong T. Nguyen ◽  
Yasusei Kudo ◽  
Maki Yoshida ◽  
Shinji Iizuka ◽  
Ikuko Ogawa ◽  
...  

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Geoffrey Williams ◽  
Carlos Neblett ◽  
Jade Arscott ◽  
Sheena McLean ◽  
Shereika Warren ◽  
...  

Abstract Kimura disease (KD) is a chronic, inflammatory, benign disorder endemic to Asia that typically manifests as a triad of painless masses in the head and neck region, elevated eosinophils and serum immunoglobulin. It usually affects young men in their second and third decades of life and is rarely seen outside of the orient. This is a report of a case of KD in a young man of African descent who presented with a cheek mass. KD was not included in our differential diagnosis, and this report highlights the need to consider this entity, which can be easily missed due to its rarity in the Western world. There is no cure for the disease, and management includes medical and surgical modalities, but local recurrence or relapse is not uncommon.


2020 ◽  
Vol 12 (1) ◽  
pp. 19-21
Author(s):  
Raghavendra Rao ◽  
Srilatha Parampalli Srinivas ◽  
Varsha M. Shetty

AbstractPerifollicular fibroma (PFF) is a rare proliferative lesion originating from the perifollicular connective tissue sheath. It may be congenital or acquired manifesting as skin colored to pink, asymptomatic papules of 1-5 mm in size. They are commonly distributed in the head and neck region. Multiple PFFs may be associated with internal malignancy or as a part of Birt-Hogg-Dube syndrome. Histopathology serves as an essential tool in clinching the diagnosis. Herein we report a case of giant congenital PFF.


2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Philipp Arens ◽  
Andrea Ullrich ◽  
Heidi Olze ◽  
Florian Cornelius Uecker

An osseous choristoma is a benign tumor consisting of regular bone tissue in an irregular localization. Choristomas in the head and neck region are rare. Most frequently, they are found in the region of the tongue or oral mucosa. There are also very few reports on osseous choristomas in the submandibular region. We present the case of a woman with a large, caudal osseous choristoma within the lateral cervical triangle. Literature review is given about all of the reported cases in the region of the neck. The pathogenesis is yet unexplained. Our case supports the theory that the development of an osseous choristoma is a reaction to a former trauma. Cervical osseous choristomas are seldom, but they represent an important differential diagnosis when dealing with a cervical tumor.


1995 ◽  
Vol 9 (1) ◽  
pp. 37-42
Author(s):  
Marc M. Kerner ◽  
Marilene B. Wang ◽  
Frank DiGregorio ◽  
Marilyn Zimmerman

Primary chondrosarcomas of the head and neck region are exceedingly rare neoplasms. These lesions have clinical and histologic characteristics that make them difficult to discern from benign chondromas. Additionally, they may arise from the periosteum, making it even more difficult to distinguish them from osteosarcomas. We present a patient with a periosteal chondrosarcoma of the maxilla. Characteristic radiologic and histologic findings associated with this lesion are described. This is the first reported case of such a lesion in the maxilla, as previous reports of periosteal chondrosarcomas have involved long bones. The diagnostic dilemma posed by this extremely unusual lesion is discussed, as well as treatment options.


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