scholarly journals A case of Giant Perifollicular Fibroma - a Diagnostic Challenge

2020 ◽  
Vol 12 (1) ◽  
pp. 19-21
Author(s):  
Raghavendra Rao ◽  
Srilatha Parampalli Srinivas ◽  
Varsha M. Shetty

AbstractPerifollicular fibroma (PFF) is a rare proliferative lesion originating from the perifollicular connective tissue sheath. It may be congenital or acquired manifesting as skin colored to pink, asymptomatic papules of 1-5 mm in size. They are commonly distributed in the head and neck region. Multiple PFFs may be associated with internal malignancy or as a part of Birt-Hogg-Dube syndrome. Histopathology serves as an essential tool in clinching the diagnosis. Herein we report a case of giant congenital PFF.

Author(s):  
Dipankar Samaddar ◽  
Ananjan Chatterjee ◽  
. Abhinandan ◽  
Deepak Kumar ◽  
. Akriti

One challenging feature of head and neck pathology is that a dizzying array of sarcomatoid lesions occurs here ranging all the way from reactive to malignant and very aggressive. This makes accurate diagnosis critical. These lesions are quite diverse with great clinical and biological heterogeneity. Some are malignant while many others are benign or simply reactive in nature. For example; at mucosal sites, a well known lesion is spindle cell carcinoma (SpCC), which are overtly malignant, and the differential diagnosis then includes a number of different malignant spindle cell lesions. However, there are several benign or even non-neoplastic lesions that can sometimes be difficult to discern from SpCC, e.g. Nodular fasciitis, Proliferative myositis, Cellular schwannoma, Benign fibrous histiocytoma, Carcino sarcoma, Sarcomatoid melanoma. Fracture callus, etc. Aim of Study: There is a diagnostic challenge to the oral pathologists to differentiate dizzying array of sarcoma like lesions from other similar microscopic simulates ranging all the way from reactive to malignant and very aggressive. This article aims to review the sarcomatoid lesions of the head and neck region with emphasis on differential diagnosis histologically and immunohistochemicaly.


2019 ◽  
Vol 8 (10) ◽  
pp. 1330-1353 ◽  
Author(s):  
Ravikumar Shah ◽  
Anurag R Lila ◽  
Ramteke-Swati Jadhav ◽  
Virendra Patil ◽  
Abhishek Mahajan ◽  
...  

Tumor-induced osteomalacia in the head and neck region remains a challenging diagnosis to manage. Literature pertaining to management and outcome details remains sparse. We describe two cohorts: cohort 1 included seven patients from a single center in Western India with tumors located in paranasal sinuses (n = 3), intracranial (n = 2) and maxilla (n = 2). The unique features from our series is the management of persistent disease with radiation therapy (n = 2) and peptide receptor radionuclide therapy (PRRT) (n = 1). Cohort two has 163 patients identified from 109 publications for systematic review. Paranasal sinuses, mandible, intracranial disease, maxilla and oral cavity, in descending order, are reportedly common tumor sites. Within this cohort, mean age was 46 ± 14 years at presentation with 44.1% having local symptoms. Duration of symptoms varied from 1 to 240 months. Pre-surgery mean serum phosphorus was 1.4 ± 0.4 mg/dL and median FGF-23 levels were 3.6 (IQR:1.8–6.8) times of normal upper limit of normal. Majority (97.5%) were managed primarily with surgical excision; however, primary radiotherapy (n = 2) and surgery combined with radiotherapy (n = 2) were also reported. Twenty patients had persistent disease while nine patients had recurrence, more commonly noted with intracranial and oral cavity tumors. Surgery was the most common second mode of treatment employed succeeded by radiotherapy. Four patients had metastatic disease. The most common histopathological diagnosis reported is PMT mixed connective tissue, while the newer terminology ‘PMT mixed epithelial and connective tissue type’ has been described in 15 patients.


Author(s):  
Mathangi Kumar ◽  
Adarsh Kudva ◽  
Ravindranath Vineetha ◽  
Monica Solomon

The head and neck region consists of several potential tissue spaces that are formed by the fascial layer. The buccal space is an area of anatomic significance due to its small size and distribution of adipose tissue. Unilateral buccal space masses often pose a diagnostic challenge owing to the diversity of tissues in the area. Here, we report four such cases of buccal space masses arising from different tissues, which presented as unilateral buccal space swelling.  This report also highlights the various causes and the differential diagnoses of unilateral buccal space masses.


Author(s):  
Prasetyanugraheni Kreshanti ◽  
Nandya Titania Putri ◽  
Valencia Jane Martin ◽  
Chaula Luthfia Sukasah

Author(s):  
Gonca Cinkara ◽  
Ginger Beau Langbroek ◽  
Chantal M. A. M. van der Horst ◽  
Albert Wolkerstorfer ◽  
Sophie E. R. Horbach ◽  
...  

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Geoffrey Williams ◽  
Carlos Neblett ◽  
Jade Arscott ◽  
Sheena McLean ◽  
Shereika Warren ◽  
...  

Abstract Kimura disease (KD) is a chronic, inflammatory, benign disorder endemic to Asia that typically manifests as a triad of painless masses in the head and neck region, elevated eosinophils and serum immunoglobulin. It usually affects young men in their second and third decades of life and is rarely seen outside of the orient. This is a report of a case of KD in a young man of African descent who presented with a cheek mass. KD was not included in our differential diagnosis, and this report highlights the need to consider this entity, which can be easily missed due to its rarity in the Western world. There is no cure for the disease, and management includes medical and surgical modalities, but local recurrence or relapse is not uncommon.


2019 ◽  
Vol 52 (4) ◽  
pp. 268-271
Author(s):  
Pinar Gulmez Cakmak ◽  
Gülsüm Akgün Çağlayan ◽  
Furkan Ufuk

Abstract Primary extranodal lymphoma is defined as a lymphoma at a solitary extranodal site, with or without involvement of the lymph nodes. The clinical and radiological features of extranodal lymphoma have been documented in recent studies. In this pictorial essay, we reviewed imaging findings of extranodal lymphoma in the head and neck region.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Han-Gyeol Yeom ◽  
Jung-Hoon Yoon

Abstract Background Concomitant cemento-osseous dysplasia (COD) and aneurysmal bone cyst (ABC) are rare in the head and neck region. In our search of the English language literature, we found only one case report describing the simultaneous occurrence of COD and ABC in the head and neck region. Here, we report a case of COD associated with ABC. Further, we performed a systematic search of the literature to identify studies on patients with COD associated with nonepithelial lined cysts of the jaws. Case presentation The patient was a 32-year-old woman who was referred from a private dental clinic because of a cystic lesion below the mandibular right first molar. She had no pain or significant systemic disease. After performing panoramic radiography and cone-beam computed tomography, the imaging diagnosis was COD with a cystic lesion, such as ABC or solitary bone cyst. Excisional biopsy was performed, which revealed concomitant COD and ABC. Conclusion This case of ABC associated with COD provides insight for the diagnostic process of radiographically mixed lesions with cystic changes.


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