scholarly journals A Mammary Nodule Mimicking Breast Cancer

2014 ◽  
Vol 99 (3) ◽  
pp. 200-202 ◽  
Author(s):  
Leonardo Solaini ◽  
Anna Bianchi ◽  
Luigi Filippini ◽  
Laura Lucini ◽  
Edda Simoncini ◽  
...  

Abstract Metastases to the breast from extramammary tumors are rare. Several clinical, radiologic, and histologic signs can help to distinguish metastases from breast primary tumors. In the present study, we present a case of a left-sided breast metastasis from renal cancer in a 44-year-old woman whose clinical presentation was a mammary nodule in the upper internal quadrant. The patient underwent quadrantectomy with sentinel lymph node biopsy. The histology revealed a clear cell carcinoma. On computed tomography scan a 5×8-cm left renal mass with pulmonary, liver, and intrapericardial nodules was found. The patient underwent palliative care and died after 4 months. Metastasis to the breast is rare, but all of those clinical, radiologic, and histologic signs more typical of extramammary malignancies should always be considered in order to choose the best treatment strategy.

Author(s):  
Hevia Palacios M ◽  
Gómez Rivas J ◽  
Tueti Silva D ◽  
Aguilera Bazán A ◽  
Martínez Piñeiro L ◽  
...  

Background: Vaginal metastasis, despite being rare, are more common than primary tumors and as presentation of the disease is extremely rare. At the time of diagnosis metastasis by hematogenous or lymphatic spread in 20-30% of patients. Case presentation: 68 years old female patient that debuted with haematuria. In the extension study we can objectify a left renal mass treated by laparoscopic radical nephrectomy. During admission the patient presented and episode of metrorragia. A lesion was found in the lower thrid of the vagina, which was biopsed, resulting a vaginal metastasis of clear cell carcinoma. The patient presented a favorable evolution being discharged four days after de surgical intervention. The subsequent extension study revealed progression of the underlying disease with mediastinal nodes and bone metastases.


2013 ◽  
Vol 20 (13) ◽  
pp. 4378-4378 ◽  
Author(s):  
Piero Covarelli ◽  
Gian Marco Tomassini ◽  
Alessandra Servoli ◽  
Franco Picciotto ◽  
Giuseppe Noya

2021 ◽  
pp. 004947552110365
Author(s):  
Abhijeet Kumar ◽  
Nirmal Prasad Shah ◽  
Narendra Pandit ◽  
Suresh Prasad Sah ◽  
Rakesh Kumar Gupta ◽  
...  

Gallbladder perforation still continues to perplex surgeons; 25 such patients diagnosed either pre- or intra-operatively and managed at our institute over the last 10 years period were analysed. Only eight were diagnosed pre-operatively, while a large majority (17) had a wrong initial working diagnosis. Symptoms and signs were variable. No blood investigation was specific. A computed tomography scan was generally better than ultrasound in detecting the perforation. All our cases were managed operatively with no mortality and a mean duration of hospital stay of 6.8 days. Most perforations were extra-hepatic (84%) and those of Niemeier’s type I (52.2%). Because of its varied clinical presentation, gallbladder perforation is often an intra-operative diagnosis, but early intervention carries a good outcome.


2019 ◽  
Author(s):  
Alexandra G Lopez-Aguiar ◽  
Kenneth Cardona

Lymphotropic sarcomas encompass a rare subset of soft tissue sarcoma histotypes known for their distinct ability to metastasize to locoregional lymph nodes. Epithelioid and clear cell sarcomas are the predominant lymphotropic subtypes and the focus of this review. The utility of lymph node assessment, whether clinical, radiographic, and/or surgical, in patients with these sarcomas is presented. The role of sentinel lymph node biopsy as well as completion lymphadenectomy in patients with these lymphotropic sarcoma histotypes is discussed. Surgery remains the only potential curative option for these tumors, and advancement in histology-specific chemotherapeutic regimens and biologic therapy options is necessary.  This review contains 6 tables and 50 references. Key words: clear cell sarcoma, completion lymphadenectomy, epithelioid sarcoma, EWS-ATF1, limb-sparing surgery, lymph node metastasis, sentinel lymph node biopsy, soft tissue sarcoma


2020 ◽  
Vol 4 (2) ◽  
pp. 232-233
Author(s):  
Drew Long ◽  
Brit Long

Case Presentation: A 55 year-old female presented to the emergency department with left sided abdominal pain and hematuria. Computed tomography scan of her abdomen and pelvis demonstrated a large left renal mass with extension into the left ureter, left renal vein, and inferior vena cava. She was admitted and treated for presumed renal cell carcinoma (RCC). Discussion: RCC may present with abdominal or flank pain and hematuria, but more commonly presents with vague symptoms. RCC should be suspected in a patient presenting with hematuria and abdominal or flank pain, especially if vague symptoms such as fatigue or anorexia are also present.


Author(s):  
Chethan P. Venkatasubba Rao ◽  
Jose Ignacio Suarez

Non-traumatic subarachnoid haemorrhage (ntSAH) is a neurological emergency. Clinical presentation is usually with severe headache, with or without abnormal neurological signs on clinical examination. NtSAH affects both males and females from 30 to 70 years, and the incidence increases with age. The incidence varies widely around the world. The gender distribution also varies in different countries, although overall the incidence is higher in women than in men. The commonest cause is rupture of an intracranial aneurysm, accounting for around 80% of cases. Diagnosis is usually by finding blood in the classical subarachnoid distribution on a cranial computed tomography scan. A number of grading systems are used to classify ntSAH.


2019 ◽  
Vol 1 (1) ◽  
pp. 48-51
Author(s):  
Prerana Kansakar ◽  
Gangadhara Sundar

A 47-year-old male presented with left sided facial cellulitis of one-week duration associated with a painful mass over the left medial canthal area. On examination, there was a firm, tender mass below the medial canthal tendon. Computed tomography scan revealed a bulky, cystic lesion at the left inferomedial orbit and medial maxilla with bony remodeling suggestive of a chronic dacryocele. The patient underwent marsupialization of the dacryocele at the inferior meatus with silicone tube intubation. His symptoms of epiphora resolved after surgery. We describe a rare clinical presentation of dacryocele in an adult and its simple, yet effective treatment option.


2003 ◽  
Vol 7 (5) ◽  
pp. 399-402 ◽  
Author(s):  
José Carlos Pascual ◽  
José Bañuls ◽  
Ma Pilar Albares ◽  
Gloria Vergara ◽  
Isabel Belinchón ◽  
...  

Background: Mastocytosis is a rare disease characterized by a primary pathological increase in mast cells in different tissues. The skin is the most frequently affected organ. Cutaneous mastocytosis, including urticaria pigmentosa, solitary mastocytoma, diffuse cutaneous mastocytosis, and telangiectasia macularis eruptiva perstans (TMEP), is usually distinguished from systemic mastocytosis. TMEP is characterized mainly by telangiectatic macules. Objective and Methods: We report a case of TMEP with an unusual clinical presentation as a solitary plaque of telangiectatic macules. A renal clear cell carcinoma was detected in a workup for systemic mastocytosis. We discuss the clinical and histological findings and treatment of TMEP. Conclusions: TMEP is a rare form of mastocytosis, which occurs mainly in adults, generally has a good prognosis, and little tendency to urticate or show constitutional symptoms. Clinicians should consider this disorder when confronted with a progressive atypical telangiectatic lesion. However, the malignant neoplasm also found in this patient is of uncertain significance.


2020 ◽  
Author(s):  
Yaohai Wu ◽  
Tong Yang ◽  
You Zuo ◽  
Shuai Fu ◽  
Zhongwei Zhao ◽  
...  

Abstract Background: The relationship between tumor-infiltrating immune cells (TIICs) and different stages or subtypes, especially the M-stage in primary tumors, remains unknown in renal clear cell carcinoma (KIRC). Therefore, the purpose of this study was to determine the relationship between TIICs and distant metastasis and provide new ideas for immunotherapy in KIRC.Methods: Clinical outcomes and transcriptome data were obtained from The Cancer Genome Atlas (TCGA) kidney cohort to characterize the composition of 22 TIICs in KIRC. Propensity score matching (PSM) and CIBERSORT were used to proceed data.Results: A bar plot, heat map, violin plot, bubble plot, box plots, and survival curves were generated. Bar plot and violin plot showed that T cells CD8 (P = 0.032), macrophages M0 (P = 0.033), macrophages M1 (P = 0.035), and mast cells resting (P = 0.001) were correlated to the M-stage. Survival curves showed that only the macrophages M0 group had a P value <0.05 (0.015) that a higher amount of macrophages M0 was associated with a better survival rate, whereas the remaining P values, including those for T cells CD8 (0.915), macrophages M1 (0.88), and mast cells resting (0.347) were >0.05. Conclusions: we got the conclusion that a low level of macrophages M0 in primary tumors was identified as a favorable factor for metastasis in renal clear cell carcinoma, which could provide us new ideas for immunotherapy in KIRC. In order to decrease the distant metastasis, more attention and focus should be paid to increase the level of macrophages M0 in primary tumors.


1996 ◽  
Vol 75 (9) ◽  
pp. 620-622 ◽  
Author(s):  
Michael A. Boggess ◽  
T. Oma Hester ◽  
Sanford M. Archer

Malignant clear cell tumors of the head and neck are uncommon. Primary tumors may arise from the salivary glands, thyroid gland, or parathyroid glands, while metastatic tumors most commonly arise from the lungs, kidneys, and female genital tract. Renal cell carcinoma is the third most common metastatic tumor to the bone and soft tissues of the head and neck. Despite this, there have been few reported cases of renal clear cell carcinoma metastases to the neck. Here we report a unique case of an otherwise asymptomatic young woman with a left neck mass as the first clinical sign of advanced renal clear cell carcinoma.


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