scholarly journals Treatment of Gharbi Type III Hepatic Hydatid Cysts: A Clinical Dilemma

2019 ◽  
Vol 104 (5-6) ◽  
pp. 232-238
Author(s):  
Adalet Elcin Yildiz ◽  
Baris Dogu Yildiz ◽  
Mesut Tez
Keyword(s):  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Meta Analysis ◽  
Treatment Options ◽  
Fluid Collection ◽  
Surgical Techniques ◽  
Public Health Problem ◽  
Hydatid Cysts ◽  
Type Iii ◽  
Clinical Dilemma

This article aims to compare available treatment options for type III liver hydatid cysts, including surgery and percutaneous techniques. Hydatid disease is a helminthic infection caused by Echinococcus granulosus and is a serious public health problem in endemic regions of the world. Hydatid cyst of the liver is the most common clinical presentation of Echinococcus granulosus. According to Gharbi classification, hydatid cysts of the liver are classified into 5 types. Type III hydatid cysts are those with fluid collection and septa. Treatment of Gharbi type III hydatid cysts is still controversial. Some researchers think that Gharbi type III hydatid cysts are not suitable for percutaneous drainage, and surgery is the suitable treatment option. There are not enough prospective studies comparing percutaneous and surgical techniques for the treatment of type III hydatid disease of the liver. A proper meta-analysis does not seem to be possible with the available studies in current medical literature.

Canine echinococcosis: the predominance of immature eggs in adult tapeworms of Echinococcus granulosus in stray dogs from Tunisia

2016 ◽  
Vol 91 (3) ◽  
pp. 380-383 ◽  
Author(s):  
W. Iraqi
Keyword(s):  
Public Health ◽  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Health Problem ◽  
Small Proportion ◽  
Public Health Problem ◽  
Hydatid Cysts ◽  
Intermediate Hosts ◽  
Stray Dogs ◽  
Adult Tapeworm

AbstractCanine echinococcosis is caused by the adult tapeworm of Echinococcus granulosus. As intermediate hosts, humans and livestock become infected following ingestion of eggs that are passed in the faeces of dogs. Mature eggs develop into hydatid cysts in different organs, leading to hydatid disease, which is a serious public health problem. In the present study, we investigated the proportion of mature eggs of E. granulosus in 140 dogs from three regions of Tunisia. The results showed the predominance of immature E. granulosus eggs in infected dogs and the occurrence of a small proportion of oncospheres. The ability of immature eggs to infect humans and livestock is discussed.

Cystic hydatid disease (Echinococcus granulosus)

2020 ◽  
pp. 1529-1533
Author(s):  
Pedro L. Moro ◽  
Hector H. Garcia ◽  
Armando E. Gonzalez
Keyword(s):  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Imaging Techniques ◽  
Clinical Manifestations ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Cystic Hydatid Disease ◽  
Control Programmes ◽  
Domestic Livestock ◽  
Cystic Hydatid

Cystic hydatid disease, caused by Echinococcus granulosus, is a zoonotic disease principally transmitted between dogs and domestic livestock, particularly sheep. Humans are infected when they ingest tapeworm eggs, with disease occurring in most parts of the world where sheep are raised and dogs are used to herd livestock. The most common clinical manifestations are cysts in the liver (typically presenting with hepatomegaly) and/or lung (presenting with cough, haemoptysis, and dyspnoea). Diagnosis is usually made on the basis of serological tests in combination with imaging techniques. Treatment options include surgery, chemotherapy with anthelminthic agents, or—for liver cysts—PAIR (puncture–aspiration–injection–reaspiration). Echinococcosis is a major public health problem in several countries. Control programmes have been aimed at educating dog owners to prevent their animals from having access to infected offal. Vaccines against sheep hydatidosis and the dog tapeworm stage are promising alternatives.

scholarly journals Articular Cartilage Defects of the Glenohumeral Joint: A Systematic Review of Treatment Options and Outcomes

Cartilage ◽  
2019 ◽  
pp. 194760351987085 ◽  
Author(s):  
Anthony Fiegen ◽  
Devin P. Leland ◽  
Christopher D. Bernard ◽  
Aaron J. Krych ◽  
Jonathan D. Barlow ◽  
...  
Keyword(s):  
Systematic Review ◽  
Patient Reported Outcomes ◽  
Glenohumeral Joint ◽  
Meta Analysis ◽  
Treatment Options ◽  
Surgical Techniques ◽  
Cartilage Defects ◽  
Imaging Findings ◽  
Level Of Evidence ◽  
Patient Reported

Objective To report radiographic and magnetic resonance imaging findings, patient-reported outcomes, and complications and/or reoperations following nonarthroplasty surgical intervention for focal glenohumeral cartilage defects. Design A literature search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Patients were included if they possessed a chondral defect of the humeral head, glenoid, or both, which had been treated with a joint preserving nonarthroplasty procedure. Risk of bias assessment was performed using the Methodological Index for Non-Randomized Studies scoring system. Study demographics, surgical technique, imaging findings, patient-reported outcomes, complications, failures, and reoperations were collected. Results Fourteen studies with 98 patients (100 shoulders) met the inclusion criteria. Patient ages ranged from 7 to 74 years. The nonarthroplasty surgical techniques utilized included microfracture (67 shoulders), osteochondral transplantation (28 shoulders), chondrocyte transplantation (4 shoulders), and internal fixation (1 shoulder). The rates of radiographic union and progression of osteoarthritis ranged between 90% to 100% and 57% to 100%, respectively. Visual analog scores ranged from 0 to 1.9 at final follow-up. Mean postoperative ASES (American Shoulder and Elbow Surgeons) shoulder scores ranged from 75.8-100. Mean postoperative CSS (Constant Shoulder Score) scores ranged from 83.3-94. Mean postoperative SSV (Subjective Shoulder Value) ranged from 70% to 99%. Failure and reoperation rates ranged between 0% to 35% and 0% to 30%, respectively, with the most common reoperation being conversion to prosthetic arthroplasty. Conclusions In this systematic review, nonarthroplasty surgical techniques demonstrated acceptable rates of radiographic healing, improved patient reported outcomes, minimal complications, and low rates of failure or reoperation. Joint preserving techniques are likely viable options to prolong function of the native shoulder and provide short- to midterm pain relief in young and highly active patients. Level of Evidence Level IV.

scholarly journals IgG4 Detection of Echinococcus granulosus Paramyosin Is a Useful Diagnostic Test for Human Hydatidosis

2013 ◽  
Vol 20 (4) ◽  
pp. 501-505 ◽  
Author(s):  
Zohreh Kazemi Moghadam ◽  
Fatemeh Ghaffarifar ◽  
Akbar Khalilpour ◽  
Farhanah Abdul Aziz ◽  
Geita Saadatnia ◽  
...  
Keyword(s):  
Echinococcus Granulosus ◽  
Sensitivity And Specificity ◽  
Public Health Problem ◽  
Parasitic Infections ◽  
Hydatid Cysts ◽  
Serum Samples ◽  
Human Igg ◽  
Two Dimensional Gel Electrophoresis ◽  
Content Type ◽  
Secondary Antibodies

ABSTRACTHydatidosis is a public health problem in many parts of the world, and improvement in diagnosis of the disease is still being pursued. Protoscoleces ofEchinococcus granulosuswere isolated from hydatid cysts collected from naturally infected sheep slaughtered in abattoirs in Iran. Sonicated extract of protoscolex was subjected to two-dimensional gel electrophoresis and Western blot analysis. Primary antibodies were from serum samples from 130 hydatidosis patients, 38 individuals infected with other parasitic infections, and 30 healthy people, whereas peroxidase (HRP)-conjugated anti-human IgG and IgG4 were used as secondary antibodies. The recombinant form of the identified protein was produced and tested for its sensitivity and specificity for the detection of human hydatidosis. An antigenic band of ∼60 kDa was found to be sensitive (82%) and specific (100%) for the detection of hydatidosis when probed with anti-human IgG4-HRP, while the sensitivity and specificity were 33 and 100%, respectively, with anti-human IgG-HRP. By mass spectrometry, the band was identified as protoscolex tegument paramyosin. The sensitivity and specificity of full-length paramyosin-recombinant protein in IgG4 blots were found to be 86 and 98%, respectively. In conclusion, IgG4 detection ofEchinococcus granulosusparamyosin was found to be useful for the diagnosis of human hydatidosis.

scholarly journals Giant intracranial hydatid cyst: A report of two cases and literature review

2012 ◽  
Vol 01 (01) ◽  
pp. 080-082 ◽  
Author(s):  
Anil Kumar ◽  
C.B. Sahay ◽  
T.J. Minj ◽  
Jeevesh Mallik
Keyword(s):  
Literature Review ◽  
Hydatid Cyst ◽  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Oral Route ◽  
Hydatid Cysts ◽  
Medical Sciences ◽  
Intracranial Hydatid Cyst

Abstract Hydatid disease is a zoonosis caused by Taenia echinococcus. The three main varieties Echinococcus granulosus, E. multilocularis and E. vogeli are primarily found in dogs and are transmitted to man by fecal–oral route. Commonly affected organs are liver, lungs and spleen. Brain is involved only in 2-5% cases. The authors herein present two cases of giant intracranial hydatid cysts managed at department of neurosurgery, Rajendra Institute of Medical Sciences, Ranchi, India.

scholarly journals Open Surgery for Hepatic Hydatid Disease

2014 ◽  
Vol 99 (6) ◽  
pp. 764-769 ◽  
Author(s):  
Erdogan Sozuer ◽  
Muhammet Akyuz ◽  
Sami Akbulut
Keyword(s):  
Hydatid Disease ◽  
Imaging Techniques ◽  
Treatment Options ◽  
Percutaneous Treatment ◽  
Surgical Approaches ◽  
High Morbidity ◽  
Hydatid Cysts ◽  
Recurrence Rates ◽  
Hepatic Hydatid Disease ◽  
Scolicidal Agent

Abstract Hydatid disease is a zoonosis caused by the larvae of Echinococcus granulosus. Humans are an intermediate host and are usually infected by direct contact with dogs or indirectly by contaminated foods. Hydatid disease mainly involves the liver and lungs. The disease can be asymptomatic. Imaging techniques such as ultrasonography and computed tomography are used for diagnosis. The growth of hydatid cysts can lead to complications. Communication between bile duct and cysts is a common complication. The goal of treatment for hydatid disease is to eliminate the parasite with minimum morbidity and mortality. There are 3 treatment options: surgery, chemotherapy, and interventional procedures. Medical treatment has low cure and high recurrence rates. Percutaneous treatment can be performed in select cases. There are many surgical approaches for managing hydatid cysts, although there is no best surgical technique, and conservative and radical procedures are used. Conservative procedures are usually preferred in endemic areas and are easy to perform but are associated with high morbidity and recurrence rates. In these procedures, the parasite is sterilized using a scolicidal agent, and the cyst is evacuated. Radical procedures include hepatic resections and pericystectomy, which have high intraoperative risk and low recurrence rates. Radical procedures should be performed in hepatobiliary centers. The most common postoperative complications are biliary fistulas and cavity-related complications. Endoscopic retrograde cholangiopancreatography can be used to diagnose and treat biliary system complications. Endoscopic sphincterotomy, biliary stenting, and nasobiliary tube drainage are effective for treating postoperative biliary fistulas.

scholarly journals Long-term results of percutaneously treated multiple hepatic and splenic hydatid cysts in a pregnant woman

2018 ◽  
Vol 12 (08) ◽  
pp. 680-682
Author(s):  
Suleyman Bakdik ◽  
Serdar Arslan ◽  
Fatih Oncu
Keyword(s):  
Pregnant Woman ◽  
Hydatid Cyst ◽  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
The Body ◽  
Long Term Results ◽  
Hydatid Cysts ◽  
Healthy Baby ◽  
Us Guidance

Hydatid disease is caused by Echinococcus granulosus, which is endemic worldwide. This parasitic tapeworm can produce cysts in almost every organ of the body; however, the liver and lungs are the most frequently targeted. 37‑year-old multigravida woman with a 10-week pregnancy in whom multiple splenic and liver hydatid cysts were detected by ultrasound. All splenic and liver hydatid cysts were treated percutaneously under US guidance during the 14th week of pregnancy. The catheterization method was used in the treatment of all hydatid cysts. Alcohol was also used as scolicidal and sclerosing agent in all procedures. There were no major complications. A cystobiliary fistula developed in a hydatid cyst treated in the liver. A healthy baby was delivered vaginally at term.

scholarly journals A benign rare intraabdominal lesion: Primary giant mesenteric hydatid cyst

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Yigit Duzkoylu ◽  
◽  
Ali Imran Kucuk ◽  
Keyword(s):  
Infectious Disease ◽  
Hydatid Cyst ◽  
Intermediate Host ◽  
Echinococcus Granulosus ◽  
Male Patient ◽  
Hydatid Disease ◽  
The Body ◽  
Parasitic Infestation ◽  
Hydatid Cysts ◽  
Primary Hydatid Cyst

Hydatid disease, mostly caused by Echinococcus granulosus, is a common parasitic infestation of the liver. In this type of infectious disease, humans are an intermediate host. Although most common sites are liver (70%) and lungs (25%), this parasitic tapeworm can be seen at any region of the body. Intraperitoneal cysts are usually secondary to the rupture of primary cysts, but primary hydatid cysts of the mesentery are very rare (%2). Herein, we aimed to report a giant primary hydatid cyst in a male patient, treated surgically without any complications.

The potential of vervet monkeys (Cercopithecus aethiops) and baboons (Papio anubis) as models for the study of the immunology of Echinococcus granulosus infections

Parasitology ◽  
1993 ◽  
Vol 106 (5) ◽  
pp. 511-517 ◽  
Author(s):  
M. T. Rogan ◽  
I. Marshall ◽  
G. D. F. Reid ◽  
C. N. L. Macpherson ◽  
P. S. Craig
Keyword(s):  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Post Infection ◽  
Significant Proportion ◽  
Cercopithecus Aethiops ◽  
Human Populations ◽  
Vervet Monkeys ◽  
Hydatid Cysts ◽  
Papio Anubis ◽  
Hydatid Fluid

SUMMARYNine vervet monkeys and nine baboons were infected with eggs of Echinococcus granulosus per as. Six of the vervets and one of the baboons possessed hydatid cysts at autopsy, 15–28 months post-infection. The sequential IgG response to hydatid fluid and protoscolex antigens showed considerable inter-animal variation. Infected vervets and baboons became seropositive after an average of 8 months post-infection. Considerable fluctuation in the IgG response was observed, particularly to the hydatid fluid antigen which, in humans, may contribute to the existence of a significant proportion of seronegative individuals. Vervets, in particular, may be useful to study immunological events associated with exposure, development and resolution of hydatid disease in outbred human populations.

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