Background: Automobile accidents (AA) stand as public health issue, being the second most prevalent cause of preventable unnatural death in Brazil. Traumatic brain injury (TBI) has a strong relationship with AA, with a high incidence of morbidity and mortality. Due to the wide spectrum of possible sequel, rehabilitation is essential to help patients to restore functionality and improve quality of life. Objectives: We sought to evaluate and characterize rehabilitation in cases of TBI, resulting from AA. Design and setting: This is an integrative literature review carried out by medical students from the University of Pernambuco. Methods: The databases BVS, PubMed and SciELO were used in this research together with the following descriptors: “Prognosis”, “Accidents, Traffic”, “Brain Injuries, Traumatic” and “Rehabilitation”. The focus was on articles published in Portuguese, Spanish and English between the years 2011 and 2021. Among the 44 articles found, only 06 were suitable to the research. Results: When compared the results of rehabilitation in specialized unit and those in non-specialized unit there were notable difference. Despite the longer hospital stay, the specialized units allowed for better recovery and greater functional independence for their patients. It was made clear that, even in cases of mild TBI, rehabilitation minimized functional impairments and improved recovering patient’s quality of life. Conclusions: It is necessary to expand the specialized units for better rehabilitation of patients with TBI, due to the treatment place being a major component in the process. The specialized units demonstrated considerable efficiency when compared to the non-specialized units.