scholarly journals Assessment of Knowledge, Attitude, and Practice to Wards Hepatitis B Prevention Among Debre Tabor Health Science College Students, South Gondar, Amhara, Ethiopia 2021

2021 ◽  
Author(s):  
Libsuye Yalgaw Zimamu ◽  
Gashaw Mekete Adal ◽  
Bisrat Dessie Getu ◽  
Gashaw Mehiret Wubet
Keyword(s):  
Hepatitis B ◽  
Health Science ◽  
Hbv Infection ◽  
Science Students ◽  
Hepatitis B Infection ◽  
B Virus ◽  
Science College ◽  
Debre Tabor ◽  
Hepatitis B Prevention ◽  
Knowledge Attitude And Practice

Abstract BACKGROUND: Hepatitis B infection is caused by the hepatitis B virus which attacks the liver and can cause both acute and chronic disease and puts people at high risk of death from cirrhosis and liver cancer. Hepatitis B virus (HBV) is a highly contagious virus which is 50-100 times more infectious than HIV but have similar mode of transmission. Hepatitis B is the most common serious liver infection in the world. Hepatitis B infection is one of the major public health problems and is the tenth leading cause of death. OBJECTIVES: The aim of this study is to assess knowledge, attitude, and practice towards hepatitis B prevention among students in Debre Tabor Health Science College. METHODS: A cross-sectional study was conducted among 422 health science students in Debre tabor, town September to october,2021. The study participants were selected using a simple random sampling technique after proportionally allocating the sample size from the total number of students, and finally study subjects was selected by systematic random sampling based on their list studying at Debre tabor health science college. The data were collected by trained data collectors using a structured self-questionnaire. The collected data were checked, coded and entered to SPSS version 20, and for data cleaning and analysis. RESULT: The response rate was 84.1% (n = 355). A total of 262(73.8%) of the students knew about the transmission of HBV infection. Majority of the students (73.5%) agreed for vaccination against HBV infection. About 10.4%, 16.3%, 5.6%, 15.5%, 10.4%, 5.1%, and 5.07% of were responds know wearing of gloves, wearing of goggles, adequate disposal of sharp materials, avoid patients diagnosed with hepatitis B, multivitamin/Blood Tonic, use antibiotics after contact, and other protective measures taken to protect against hepatitis B infection students knew about the preventive measures against HBV infection. CONCLUSION: The overall awareness regarding HBV disease was found to be deficient among the health science students.

scholarly journals Assessment of Knowledge and Practice on Hepatitis B Infection Prevention and Associated Factors among Health Science Students in Woldia University, Northeast Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Teshome Gebremeskel ◽  
Tirfe Beshah ◽  
Mulugeta Tesfaye ◽  
Biruk Beletew ◽  
Ayelign Mengesha ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Associated Factors ◽  
Infection Prevention ◽  
Health Science ◽  
Science Students ◽  
Hepatitis B Infection ◽  
Health Science Students ◽  
B Virus ◽  
Knowledge And Practice

Background. Hepatitis B virus is a global problem, with 66% of all the world population living in areas where there are high levels of infection. HBV is the leading risk factor for HCC globally and accounts for at least 50% of cases of HCC. Medical and health science students, being part of the health-care system, are exposed to the infection as a risk as other health-care workers when they come in contact with patients and contaminated instruments. Objective. The main aim of this study was to assess the knowledge and practice of hepatitis B virus infection prevention and its associated factors among health science students in Woldia University. Methods. Institutional-based cross-sectional study was conducted from January 30 to May 30, 2019, among health science students of Woldia University who had previous clinical attachments. Two hundred students were selected by the systematic random sampling method. Association of dependent and independent variables was computed using a bivariable and multivariable logistic regression model. P<0.05 was considered as significantly associated. Result. The study revealed that, out of 200 participants, 96 (48%) have poor knowledge, whereas 104 (52%) showed good knowledge about HBV. Regarding the practice of participants, 79 (39.5%) of the students have good practice to prevent HBV, whereas 121 (59.5%) had poor practice towards HBV infection prevention. Conclusion. Based on the current study, greater than half of the students who participated in the study have good knowledge of hepatitis B infection prevention and most of the students have poor practice about infection prevention of hepatitis B virus.

scholarly journals Knowledge attitude and practice on prevention of hepatitis B infection among medical students of a tertiary care centre in Tamil Nadu, India

2020 ◽  
Vol 8 (2) ◽  
pp. 492
Author(s):  
Vasantha Mallika M. C. ◽  
Sivaanusuya S.
Keyword(s):  
Hepatitis B Virus ◽  
Medical Students ◽  
High Risk ◽  
Hepatitis B ◽  
Hbv Infection ◽  
Vaccine Uptake ◽  
Hepatitis B Infection ◽  
Attitude And Practice ◽  
B Virus ◽  
Knowledge Attitude And Practice

Background: Hepatitis B infection is a serious global public health problem. About two billion people are infected with hepatitis B Virus (HBV) all over the world. The prevalence of HBV infection in India is 4%(2%-8%) with more prevalence among health care workers. Medical students represent a group that is at high-risk for acquiring and spreading hepatitis B infection. Despite increasing prevalence of HBV infection, there is paucity of knowledge, attitude and practice on HBV among medical students. Objective of the study was to assess the knowledge, attitude and practices on prevention of hepatitis B infection among medical students of Sree Mookambika Institute of Medical Sciences, Kulasekharam.Methods: A cross sectional study was conducted among 205 MBBS students using a pretested self-administered questionnaire for assessing the knowledge, attitude, and practice on prevention of HBV infection after obtaining informed consent from the participants.Results: Among 205 MBBS students, correct response towards Knowledge, Attitude, and Practices were given by 77.07%, 77.56%, and 76.59% respectively, 79.5% of the students were fully vaccinated; 20.5% were partially vaccinated against Hepatitis B Virus infection.Conclusions: The medical students are at a very high risk of contracting HBV infection during their training period in view of low HBV vaccine uptake rate and high chance of accidental exposure to blood infected with HBV. Creating awareness among medical students on various aspects of Hepatitis B infection through health education programs before their exposure in medical colleges and subjecting them to active immunization against HBV are mandatory to control the spread of Hepatitis B viral infection.

scholarly journals Deficient Knowledge on Hepatitis B Infection in Pregnant Women and Prevalence of Hepatitis B Surface Antigen Carriage in an Endemic Area: A Review

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Oi Ka Chan ◽  
Terence T. Lao ◽  
Stephen S. H. Suen ◽  
Tak Yeung Leung
Keyword(s):  
Hepatitis B ◽  
Hepatitis B Surface Antigen ◽  
Hbv Infection ◽  
Hepatitis B Infection ◽  
Sources Of Information ◽  
Immunization Programme ◽  
B Virus ◽  
High Prevalence ◽  
Endemic Areas ◽  
Potential Factors

Hepatitis B infection is a major global health problem. Vertical transmission is the commonest route of spreading hepatitis B virus (HBV) in many endemic areas. In order to control such transmission in Hong Kong, neonatal immunization programme was implemented for more than two decades. A declining prevalence of HBV infection was expected. However, the prevalence remained unabated at around 10% in recent studies. We suspect that one of the explanations of this persistent high prevalence is deficient knowledge on infection with the HBV and its prevention. Our paper gives an overview of the knowledge on HBV infection among Chinese population in both high and low endemic areas and discusses the potential factors that influenced the knowledge on as well as the implication of the sources of information for HBV infection, which was not addressed in previous studies.

scholarly journals Knowledge, Attitude, and Practice towards Hepatitis B Virus among Pregnant Women Attending Antenatal Care at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Teklay Gebrecherkos ◽  
Getu Girmay ◽  
Mulualem Lemma ◽  
Markos Negash
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Hbv Infection ◽  
Attitude And Practice ◽  
Specialized Hospital ◽  
B Virus ◽  
The University ◽  
Mother To Child ◽  
Knowledge Attitude And Practice

Background. Hepatitis B virus (HBV) infection remains a serious public health concern worldwide. Mother-to-child transmission (MTCT) is the major mode in endemic areas, including Ethiopia, where little is known about pregnant women’s knowledge, attitudes, and practice towards HBV infection and MTCT. Therefore, the study is aimed at determining the knowledge, attitude, and practice towards HBV among pregnant women attending antenatal care. Method. A cross-sectional study was conducted from February to April 2018, at the University of Gondar Comprehensive Specialized Hospital. A total of 354 pregnant women were selected by systematic random sampling and included in this study. KAP of participants on HBV MTCT was assessed using a structured questionnaire. Data was analyzed using SPSS version 22 software. Result. The total response rate was 100% (354/354). Out of the 354 participants, 73.4% were within the poor knowledge. Only 18.9% of the respondents know HBV can be transmitted from mother to child during pregnancy. Less than half (43.8) of the participants think that they will never be infected with HBV, and 47.7% of them go to traditional healers when they have symptoms of HBV. Majority of the respondents (85.87%) had never screened for HBV, and only 28.5% of the participants believed that hepatitis B can cause liver cancer. In multivariable analysis, residence, income, and educational level were associated with mean score knowledge and attitude. Conclusions. Knowledge about HBV among pregnant women was found to be poor, and their attitude and practice were also limited. Therefore, extensive health education program should be given to the pregnant women to increase their awareness towards HBV infection. All pregnant women should be screened for HBV as part of ANC follow-up.

scholarly journals Prevalence and risk factors of hepatitis B virus infection among medical laboratory science students in a Ghanaian tertiary institution

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Philip Apraku Tawiah ◽  
Albert Abaka-Yawson ◽  
Emmanuel Sintim Effah ◽  
Kingsley Arhin-Wiredu ◽  
Kwabena Oppong
Keyword(s):  
Risk Factors ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Hbv Infection ◽  
Medical Laboratory ◽  
Science Students ◽  
Content Type ◽  
Medical Laboratory Science ◽  
Laboratory Science ◽  
B Virus

PurposeThis study aimed to determine the prevalence and risk factors of hepatitis B virus (HBV) infection among medical laboratory science students (MLSSs) in the University of Health and Allied Sciences (UHAS), Ghana.Design/methodology/approachA cross-sectional study design was employed to recruit a total of 178 students into the study. A self-administered questionnaire was used to gather relevant information on risk factors, and a hepatitis B diagnostic test kit was used to test for HBV infection. Descriptive, chi-square test, bivariate and multiple logistic regression statistical analysis were computed. Significance was observed at p < 0.05.FindingsThe prevalence of HBV infection among MLSSs was 6.7%. Torn gloves and splash of blood and body fluids contributed to 43.0% and 28.0% of all the risk factors of HBV infection, respectively. Also, 43.3% of students had received at least one dose of the hepatitis B vaccination. Sharp object-related injury and torn gloves increased the odds of HBV infection, while vaccination decreased the odds of HBV infection.Research limitations/implicationsSharp-related injuries, torn gloves and vaccination were strong predictors of the HBV infection. And since the infection among students was high, it is imperative to institute measures to avert the concentration of the disease among health-care workers (HCWs) and MLSSs.Originality/valueThis study reveals the prevalence of HBV among MLSSs, who are recognized as being among the high-risk student populations aside from student nurses.

How Far we are towards Eradication of HBV Infection

2015 ◽  
Vol 24 (4) ◽  
pp. 473-479 ◽  
Author(s):  
Mihai Voiculescu
Keyword(s):  
Immune Response ◽  
Hepatitis B Virus ◽  
T Cell ◽  
Hepatitis B ◽  
T Cell Receptors ◽  
Hepatitis B Surface Antigen ◽  
Hbv Infection ◽  
Major Health Problem ◽  
Cell Receptors ◽  
B Virus

Hepatitis B virus (HBV) infection is a major health problem with an important biological and a significant socio-economic impact all over the world. There is a high pressure to come up with a new and more efficient strategy against HBV infection, especially after the recent success of HCV treatment. Preventing HBV infection through vaccine is currently the most efficient way to decrease HBV-related cirrhosis and liver cancer incidence, as well as the best way to suppress the HBV reservoir. The vaccine is safe and efficient in 80-95% of cases. One of its most important roles is to reduce materno-fetal transmission, by giving the first dose of vaccine in the first 24 hours after birth. Transmission of HBV infection early in life is still frequent, especially in countries with high endemicity.Successful HBV clearance by the host is immune-mediated, with a complex combined innate and adaptive cellular and humoral immune response. Different factors, such as the quantity and the sequence of HBV epitope during processing by dendritic cells and presenting by different HLA molecules or the polymorphism of T cell receptors (TOL) are part of a complex network which influences the final response. A new potential therapeutic strategy is to restore T-cell antiviral function and to improve innate and adaptive immune response by immunotherapeutic manipulation.It appears that HBV eradication is far from being completed in the next decades, and a new strategy against HBV infection must be considered. Abbreviations: ALT: alanine aminotransferase; APC: antigen presenting cells; cccDNA: covalently closed circular DNA; HBIG: hepatitis B immunoglobulin; HbsAg: hepatitis B surface antigen; HBV: hepatitis B virus; HCC: hepatocellular carcinoma; CTL: cytotoxic T lymphocyte; IFN: interferon; NUC: nucleos(t)ide analogues; pg RNA: pre genomic RNA; TLR: toll-like receptors; TOL: T cell receptors.

Gianotti-Crosti syndrome associated with hepatitis B virus (HBV) infection in an adult: a case report

Kanzo ◽  
2010 ◽  
Vol 51 (11) ◽  
pp. 615-619
Author(s):  
Yuichi Honma ◽  
Masaru Harada ◽  
Masaaki Hiura ◽  
Ryoichi Narita ◽  
Shintaro Abe ◽  
...  
Keyword(s):  
Case Report ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Hbv Infection ◽  
B Virus

scholarly journals 1066. Immune Escape Mutant Detection Using Commercially Available Methods for Hepatitis B Surface Antigen Serological Testing

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S562-S562
Author(s):  
Robert Gish ◽  
Vincent Streva
Keyword(s):  
Hepatitis B ◽  
Immune Escape ◽  
Hepatitis B Surface Antigen ◽  
Panel Member ◽  
The United States ◽  
Hbv Infection ◽  
Hepatitis B Vaccination ◽  
Review Panel ◽  
B Virus ◽  
Escape Mutants

Abstract Background Although overall infection rates of Hepatitis B virus (HBV) in the United States (US) remain stable, as many as 2.2 million persons are still chronically infected with Hepatitis B Virus (HBV)1. Persons who inject drugs (PWID) are at a higher risk of HBV infection and since 2009 three states (KY, TN, WV) have reported up to a 114% increase in cases of acute HBV infection due to higher infection rates among a non-Hispanic white populations (30–39 years), and injection drug users2. Hepatitis B vaccination is recommended as primary prevention for adults who are at increased risk for HBV infection, including PWID. However, data from the National Health Interview Survey indicate that hepatitis B vaccination coverage is low among adults in the general population3, and it is likely to be lower among injection drug users. Hepatitis B Surface Antigen (HBsAg) is the first serological marker to appear after HBV exposure and infection; this marker is included in the recommended panel for acute hepatitis diagnosis and accurate detection is necessary for early and accurate diagnosis. Serological testing challenges exist for HBsAg due to the high degree of genetic variability which can further be exacerbated by endogenous and exogenous pressures. The immuno-dominant region may have one or more mutations described as immune escape mutations which can decrease or abrogate HBsAg binding to antibodies used in immunoassays. Although the prevalence of these mutations is not well documented in the United States, international studies have shown that up to 79% of HBV-reactivated patients (vs 3.1% of control patients; p&lt; 0.001) carry HBsAg mutations localized in immune-active HBsAg regions4. Methods A study was conducted using a panel of 10 unique recombinant HBsAg immune escape mutants. Panel members were tested by commercially available HBsAg serological immunoassays. Results It was found that although commercially available HBsAg immunoassays are the primary diagnostic tool for HBV diagnosis, not all HBsAg immune escape mutants are detected, with some method detecting as few as 5 out of 10 of these mutant samples. Figure 1 Conclusion Improvement is needed in commercially available methods for the accurate detection of HBsAg. Disclosures Robert Gish, MD, Abbott (Consultant)AbbVie (Consultant, Advisor or Review Panel member, Speaker’s Bureau)Access Biologicals (Consultant)Antios (Consultant)Arrowhead (Consultant)Bayer (Consultant, Speaker’s Bureau)Bristol Myers (Consultant, Speaker’s Bureau)Dova (Consultant, Speaker’s Bureau)Dynavax (Consultant)Eiger (Consultant, Advisor or Review Panel member)Eisai (Consultant, Speaker’s Bureau)Enyo (Consultant)eStudySite (Consultant, Advisor or Review Panel member)Exelixis (Consultant)Fujifilm/Wako (Consultant)Genentech (Consultant)Genlantis (Consultant)Gilead (Consultant, Advisor or Review Panel member, Speaker’s Bureau)GLG (Consultant)HepaTX (Consultant, Advisor or Review Panel member)HepQuant (Consultant, Advisor or Review Panel member)Intercept (Consultant, Speaker’s Bureau)Ionis (Consultant)Janssen (Consultant)Laboratory for Advanced Medicine (Consultant)Lilly (Consultant)Merck (Consultant)Salix (Consultant, Speaker’s Bureau)Shionogi (Consultant, Speaker’s Bureau)Viking (Consultant)

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