This chapter launches a new investigation of the question of God’s existence, examining it against the reality of human suffering and bringing to the fore contentious presuppositions concerning agency and value at the core of the debate. When we survey the world, we observe an enormous amount of pain, including virtually unspeakable kinds of maltreatment and agony, many instances of which seem patently unfair, unearned, and pointless. This chapter initiates the book’s argument that, in light of these observations, it is reasonable to conclude that God does not exist. The chapter critically examines and extends the work of William Rowe, John Hick, and Alvin Plantinga, taking up apparently pointless instances of suffering and the proposed justifying goods of character-building and free will.