Two supramolecular compounds constructed by polyacid anion clusters: Synthesis, characterization and performance research

In this paper, two novel organic-inorganic hybrid supramolecule compounds {[Cu·L1’·H2O]·(α-Mo8O26)0.5}n 1 and compound {[Cu·L2’·H2O]·(α-Mo8O26)0.5}n 2 have been synthesized [L1’ = 1, 3-bis (4-carboxylpyridine) propane dibromide, L2’ = 1, 4-bis (4-carboxylpyridine) butane dibromide]. Compounds 1 and 2 have been expressly confirmed by PXRD, IR, X-ray single crystal diffraction and TG. Last, the study found that compounds 1 and 2 have obvious adsorption effects on MB and RhB organic dyes, and compound 2 has high adsorption capacity for MB.

Structural characterisation methods for supramolecular chemistry that go beyond crystallography

In this tutorial review, we present an introduction to structural characterisation techniques commonly used for non-crystalline supramolecular compounds and discuss their application based on recent case studies.

Structure-Activity Relationship of Supramolecular Compounds in Drug Delivery

Abstract:: Supramolecular compounds are capable of undergoing various non-covalent interactions with other molecules like host-guest chemistry, controlled encapsulation, hydrophobic interactions, variety of delivering strategies, electron af-finity induced interactions, etc. These properties of supramolecular compounds make them attractive to be effective drug carriers. This review will detail about the recent interesting reports on the structure-activity relationship of supramolecular compounds in drug delivery. The supramolecular compounds considered are cyclodextrins, cucurbiturils, avidin, biotin, ro-taxanes, viologens, and dendrimers. Studying the opportunities given by these supramolecular compounds in drug delivery will open a way for the novel efficient drug delivery systems for the future.

An outline of the use of supramolecular compounds in biology and medicine

Supramolecular chemistry opened up opportunities and prospects in biological studies. Numerous supramolecular systems are known which assume different shapes depending on the structure of the component molecules. Some of them are mixed systems. Ribbon-like supramolecular structures which are the main focus of this paper form complexes with proteins in a way which is a new type of interaction. Despite preserving the ribbon-like structure, it may also interact with proteins as a mixed system. In this way, it may be used as a carrier of drugs. In addition, hybrid systems created by a combination of ribbon-like supramolecular structures with carbon nanotubes were presented together with data from studies of these structures as drug-carrying systems. This paper presents an outline of the experimentally confirmed possible use of ribbon-like supramolecular systems.