Utilization of direct forcing immersed boundary methods for the optimization of inertial focusing microfluidics

Inertial focusing microfluidics have gained significant momentum in the last decade for their ability to separate and filter mixtures of particles and cells based on size [1-3]. However, the most important feature is that the separation is passive, without the need for external forces. At the heart of inertial focusing is the balance between counteracting lift forces: shear and wallinduced lift. Shear-induced lift is a product of the curvature of the fluid flow and the rotation of the particle in the flow, while wall-induced lift is generated by the disturbance of the fluid by the particle near a wall. This phenomenon was first observed by Segre and Silberberg for the focusing of particles in a pipe, and was later extended to the focusing of cells and particle in rectangular channels [4]. Taking advantage of inertial focusing we explore particle capture utilizing an expanded channel microfluidics chip design. By expanding a small region of the straight channel microvortices form in the well, which allows for size selective trapping of particles.

Migration and Alignment of Three Interacting Particles in Poiseuille Flow of Giesekus Fluids

Effect of rheological property on the migration and alignment of three interacting particles in Poiseuille flow of Giesekus fluids is studied with the direct-forcing fictitious domain method for the Weissenberg number (Wi) ranging from 0.1 to 1.5, the mobility parameter ranging from 0.1 to 0.7, the ratio of particle diameter to channel height ranging from 0.2 to 0.4, the ratio of the solvent viscosity to the total viscosity being 0.3 and the initial distance (y0) of particles from the centerline ranging from 0 to 0.2. The results showed that the effect of y0 on the migration and alignment of particles is significant. The variation of off-centerline (y0 ≠ 0) particle spacing is completely different from that of on-centerline (y0 = 0) particle spacing. As the initial vertical distance y0 increased, the various types of particle spacing are more diversified. For the off-centerline particle, the change of particle spacing is mainly concentrated in the process of cross-flow migration. Additionally, the polymer extension is proportional to both the Weissenberg number and confinement ratio. The bigger the Wi and confinement ratio is, the bigger the increment of spacing is. The memory of shear-thinning is responsible for the reduction of d1. Furthermore, the particles migrate abnormally due to the interparticle interaction.

Modelling Cross-Shore Shoreline Change on Multiple Timescales and Their Interactions

In this paper, a new approach to model wave-driven, cross-shore shoreline change incorporating multiple timescales is introduced. As a base, we use the equilibrium shoreline prediction model ShoreFor that accounts for a single timescale only. High-resolution shoreline data collected at three distinctly different study sites is used to train the new data-driven model. In addition to the direct forcing approach used in most models, here two additional terms are introduced: a time-upscaling and a time-downscaling term. The upscaling term accounts for the persistent effect of short-term events, such as storms, on the shoreline position. The downscaling term accounts for the effect of long-term shoreline modulations, caused by, for example, climate variability, on shorter event impacts. The multi-timescale model shows improvement compared to the original ShoreFor model (a normalized mean square error improvement during validation of 18 to 59%) at the three contrasted sandy beaches. Moreover, it gains insight in the various timescales (storms to inter-annual) and reveals their interactions that cause shoreline change. We find that extreme forcing events have a persistent shoreline impact and cause 57–73% of the shoreline variability at the three sites. Moreover, long-term shoreline trends affect short-term forcing event impacts and determine 20–27% of the shoreline variability.

Diverse manifestations of insolation forcing of environmental changes during the middle Piacenzian

<p>The middle Piacenzian period is the closest sustained warm interval and a possible analog to the future climate. It is well known that global ice volume exhibits dominant 41-kyr cyclicities. However, high resolution terrestrial paleoenvironmental records are scare. Here we present a 3.6 kyr terrestrial environmental variation record from Teruel Basin of Spain and compare the results with the East Asian monsoon records. The Spain results show dominant 41-kyr cycles during the early Piacenzian (3.3-3.15 Ma) when eccentricity was at minimum, but the 41-kyr cycles weakens during the late Piacenzian 3.15-2.95 Ma when eccentricity got increased, suggesting direct forcing by insolation. This pattern is different from the monsoonal records from China, which demonstrates persistent 20-kyr cycles during the entire middle Piacenzian. The strong 41-kyr cycles in westerly region during the early Piacenzian may originate from its higher latitude and higher sensitivity to insolation gradient forcing.</p>