If intellectualism about knowledge-how is true (and so, if knowledge-how is a species of knowledge-that), then to the extent that we need an autonomy condition on know-how, it will be (simply) an autonomy condition on know-that: a condition on propositional knowledge-apt belief. However, the anti-intellectualist—according to whom know-how is fundamentally dispositional rather than propositional—would need an entirely different story here––one that places an autonomy-related restriction not on propositional-knowledge-apt belief but, instead, on know-how-apt dispositions. Chapter 4 develops exactly this kind of restriction, by cobbling together some ideas about know-how and virtue epistemology with recent thinking in the moral responsibility literature about freedom, responsibility, and manipulation. The proposal is that one is in a state of knowing how to do something, φ, only if one has the skill to φ successfully with guidance control, and one’s φ-ing exhibits guidance control (and furthermore, manifests know-how) only if one’s φ-ing is caused by a reasons-responsive mechanism that one owns. Unsurprisingly, the devil is in these details—and this chapter aims to spell them out in a way that rules out certain kinds of radical performance enhancing cases while not ruling out that, say, one knows how to do a maths problem when one’s performance is just mildly boosted by Adderall.