Mixed Variant of Acrokeratosis verruciformis of Hopf: A rare entity

Acrokeratosis verruciformis of Hopf (AKV) is a rare autosomal dominant genodermatosis of unknown etiology. Here we present a case of a 20-year-female with multiple skin-colored flat papules over the dorsum of hands and feet interspersed with multiple hypopigmented macular lesions of 5 years duration. No family member showed a similar lesion. The presence of classical AKV with absent family history and definite histopathology findings make this case an unusual and rare entity.

Derivation and Verification of the Relationship between Ablation Index and Baseline Impedance

Objective. To explore the quantitative adjustment of ablation index (AI) under different baseline impedance to achieve similar lesion dimensions. Methods. (1) Keeping the AIs relatively constant, the lesion dimensions in different baseline impedances were studied. (2) According to Joule's law, Q = I2RT, keeping the current (I) unchanged, the powers corresponding to different baseline impedances can be obtained. Under different baseline impedances and corresponding powers, the swine hearts were ablated for 30 s in simulated human circumstances. The baseline impedances, the lesion dimensions, and AIs were recorded. And the derivation of empirical formula was achieved according to the AIs and baseline impedance values in similar lesions dimension. (3) Basic AI and baseline impedance (AI0/R0) were set as 400/120 Ω in the common AI groups and 550/120 Ω in the high AI groups, AI values in different baseline impedances were calculated using the empirical formula, and the corresponding lesion dimensions were measured to verify this formula. Results. (1) Higher baseline impedances were related to smaller lesion dimensions at similar AIs. (2) The lesion dimensions were roughly the same after modulating the baseline impedance and power to keep the electric current relatively constant. The relationship between AI and R fitted with experimental data is AI = 1.9933R + 203.61 (r = 0.9649), and the formula derived is ΔAI = (AI0 − 203)/R0 × ΔR. (3) Under the guidance of the empirical formula, there was no significant difference in lesion dimensions between the standard group and the formula guiding groups when AI0 = 400, but there was a shrinking tendence when AI > 700. Conclusion. The lesion depths are negatively correlated with baseline impedance at a certain AI. The relationship between baseline impedance and AI is “ΔAI = (AI0 − 203)/R0 × ΔR”. It is verified that when the AI is not too high, the empirical formula can be used to guide the quantitative adjustment of AIs at different baseline impedance, and the lesion depths achieved are roughly the same.

Cutaneous Lymphadenoma: A Case of Recurrence after Shave Excision

Cutaneous lymphadenoma (CL) is a rare skin tumor supposedly derived from the pilosebaceous unit. Since its description in 1987, fewer than 60 cases have been documented. Herein we report a case of CL presenting as a small nodule on the forehead of a young female. The lesion recurred two years after shave excision of a similar lesion. The histopathological examination revealed interconnected islands, sheets, and trabeculae consisting of two distinct types of cells within a sclerotic stroma, a peripheral rim of palisading basophilic cells, and central epithelial cells with eosinophilic to clear cytoplasm. A dense infiltration with prominent lymphocytes and few plasma cells dominated the stroma and permeated the epithelial nests. This case represents the recurrence of this type of skin tumor after shave excision and thus highlights the importance of complete margin-free excision of such lesions.

Fungoide Mycosis. Case report

To report the case of a 63-years-old female referred to the Oculoplastic Eyelid and Orbit Department of the ICO "Ramón Pando Ferrer" for two lesions in the left upper eyelid, the biggest one, a 20 mm nodule with a central ulcer full of debris and discharge. It was treated with antibiotics without improvement; a biopsy was carried out with a preliminary report of Mycosis Fungoides. A similar lesion appeared on the lower eyelid after surgery and was treated with perilesional HeberFERON injections, disappearing after three weeks. The final histopathology analysis revealed a Non-Hodgkin skin lymphoma with a high malignancy grade. Conclusions: Diagnosing Mycosis fungoides is difficult in early stages or atypical presentations. It's essential to know this disease and its stages to set it apart from entities with similar characteristics, aiming for an early diagnosis, treatment, and proper follow-up.

Multicentric Hemangiopericytoma of Posterior Fossa: A Rare Case and Review of Literature

Intracranial hemangiopericytoma is unusual, and those occurring in the posterior fossa are extremely rare. Surgery followed by radiotherapy is the mainstay of treatment. These tumors are known to recur locally and distant metastases are reported. Multicentricity either in the primary setting or in recurrent setting is rarely reported. We report here a rare case of multicentric posterior fossa hemangiopericytoma occurring in a 38-year-old man at two different intervals. The patient underwent total excision of right tentorial hemangiopericytoma in 2013, followed by radiotherapy. After being free from disease for 3 years, he developed a similar lesion on left tentorial leaflet in 2016 for which a total excision was once again done followed by adjuvant radiotherapy.

Repeated hydrocephalus in recurrent intraventricular neurocysticercosis: An uncommon presentation

ABSTRACTA rare case of a 42-years old man presented with repeated hydrocephalus due to the neurocysticercosis cyst (NCC) in the lateral ventricle. Patient was operated previously 2½ years back for a similar lesion at same site. Both times he was treated endoscopically with removal of the cyst. Interestingly there was no parenchymatous lesion at any stage of follow up. Isolated recurrent intraventricular NCC is a rare condition that has never been reported in the literature.