hydrazone bond
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Formation of supramolecular nanostructures via in situ self-assembly and post-assembly modification of a biocatalytically constructed dipeptide hydrazide

2021 ◽  
Author(s):  
Yuki Shintani ◽  
Taku Ohtomi ◽  
Aya Shibata ◽  
Yoshiaki Kitamura ◽  
Koichiro M. Hirosawa ◽  
...  
Keyword(s):  
Self Assembly ◽  
Bond Formation ◽  
Hydrazone Bond ◽  
Supramolecular Architectures ◽  
Aqueous Conditions

The in situ self-assembly of a biocatalytically constructed dipeptide hydrazide gives rise to supramolecular hydrogels, consisting of networks of supramolecular nanoarchitectures, under mild aqueous conditions. Moreover, the post-assembly modification via hydrazone bond formation enables the decoration of the prefabricated supramolecular architectures.

Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin

2021 ◽  
pp. 120872
Author(s):  
Shen-Jun Yuan ◽  
Chao Wang ◽  
Hua-Zhen Xu ◽  
Yan Liu ◽  
Mei-Yan Zheng ◽  
...  
Keyword(s):  
Intracellular Distribution ◽  
Hydrazone Bond

Salt endurable and shear resistant polymer systems based on dynamically reversible acyl hydrazone bond

2021 ◽  
pp. 117083
Author(s):  
Ruiying Wu ◽  
Shuai Zhang ◽  
Yanru Chen ◽  
Hao Chen ◽  
Minggang Wang ◽  
...  
Keyword(s):  
Polymer Systems ◽  
Hydrazone Bond ◽  
Acyl Hydrazone

Selective recognition of a cyclic peptide hormone in human plasma by hydrazone bond-oriented surface imprinted nanoparticles

2021 ◽  
Vol 1154 ◽  
pp. 338301
Author(s):  
Huiqing Hou ◽  
Yulong Jin ◽  
Kun Xu ◽  
Le Sheng ◽  
Yanyan Huang ◽  
...  
Keyword(s):  
Human Plasma ◽  
Cyclic Peptide ◽  
Peptide Hormone ◽  
Selective Recognition ◽  
Oriented Surface ◽  
Hydrazone Bond

scholarly journals Nucleophilic catalysis of p-substituted aniline derivatives in acylhydrazone formation and exchange

2021 ◽  
Author(s):  
Andrea Canal-Martín ◽  
Claudio Daniel Daniel Navo ◽  
Elena Sáez ◽  
Dolores Molero ◽  
Gonzalo Jiménez-Osés ◽  
...  
Keyword(s):  
Combinatorial Chemistry ◽  
Bond Formation ◽  
Nucleophilic Catalysis ◽  
Dynamic Combinatorial Chemistry ◽  
Physiological Conditions ◽  
Hydrazone Bond ◽  
Aniline Derivatives ◽  
Research Fields ◽  
Reversible Reactions

Hydrazone bond formation is a versatile reaction employed in several research fields. It is one of the most popular reversible reactions in dynamic combinatorial chemistry. Under physiological conditions, hydrazone exchange...

scholarly journals Synthesis of glycoimmunogen Tn-Thr-PS A1 via hydrazone bond and stability optimization of PS A1 monosaccharide mimics under vaccine development conditions

2020 ◽  
Vol 39 (2-3) ◽  
pp. 107-129 ◽  
Author(s):  
F. Hossain ◽  
S. Nishat ◽  
S. Ghosh ◽  
S. Boga ◽  
G. T. Hymel ◽  
...  
Keyword(s):  
Vaccine Development ◽  
Hydrazone Bond

scholarly journals ATP-fuelled self-assembly to regulate chemical reactivity in the time domain

2020 ◽  
Vol 11 (6) ◽  
pp. 1518-1522 ◽  
Author(s):  
Maria A. Cardona ◽  
Leonard J. Prins
Keyword(s):  
Time Domain ◽  
Self Assembly ◽  
Chemical Reactivity ◽  
Bond Formation ◽  
Complex Mixture ◽  
Hydrazone Bond ◽  
The Time Domain

The addition of ATP under dissipative conditions to a complex mixture causes the transient upregulation of hydrazone-bond formation.

Chemical stimulus-responsive supramolecular hydrogel formation and shrinkage of a hydrazone-containing short peptide derivative

Soft Matter ◽  
2020 ◽  
Vol 16 (4) ◽  
pp. 899-906 ◽  
Author(s):  
Takumi Sugiura ◽  
Takurou Kanada ◽  
Daisuke Mori ◽  
Hiroyuki Sakai ◽  
Aya Shibata ◽  
...  
Keyword(s):  
Exchange Reaction ◽  
Chemical Stimulus ◽  
Supramolecular Hydrogel ◽  
Short Peptide ◽  
Hydrazone Bond ◽  
Stimulus Responsive ◽  
Hydrogel Formation ◽  
Peptide Derivative

Herein, we describe a short peptide derivative containing a hydrazone bond showing transient hydrogel formation triggered by hydrazone–oxime exchange reaction.

scholarly journals Targeted pharmacokinetics of polymeric micelles modified with glycyrrhetinic acid and hydrazone bond in H22 tumor-bearing mice

2019 ◽  
Vol 34 (1) ◽  
pp. 141-151 ◽  
Author(s):  
Yan Zheng ◽  
Shudan Shi ◽  
Yaru Liu ◽  
Yandan Zhao ◽  
Yuqi Sun
Keyword(s):  
Polymeric Micelles ◽  
Glycyrrhetinic Acid ◽  
Hydrazone Bond ◽  
Tumor Bearing

scholarly journals PEG and PEG-peptide based doxorubicin delivery systems containing hydrazone bond

2018 ◽  
Vol 25 (4) ◽  
Author(s):  
Beste Balcı ◽  
Ayben Top
Keyword(s):  
Delivery Systems ◽  
Hydrazone Bond ◽  
Doxorubicin Delivery
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