Formation of supramolecular nanostructures via in situ self-assembly and post-assembly modification of a biocatalytically constructed dipeptide hydrazide

The in situ self-assembly of a biocatalytically constructed dipeptide hydrazide gives rise to supramolecular hydrogels, consisting of networks of supramolecular nanoarchitectures, under mild aqueous conditions. Moreover, the post-assembly modification via hydrazone bond formation enables the decoration of the prefabricated supramolecular architectures.

Nucleophilic catalysis of p-substituted aniline derivatives in acylhydrazone formation and exchange

Hydrazone bond formation is a versatile reaction employed in several research fields. It is one of the most popular reversible reactions in dynamic combinatorial chemistry. Under physiological conditions, hydrazone exchange...

ATP-fuelled self-assembly to regulate chemical reactivity in the time domain

The addition of ATP under dissipative conditions to a complex mixture causes the transient upregulation of hydrazone-bond formation.

Chemical stimulus-responsive supramolecular hydrogel formation and shrinkage of a hydrazone-containing short peptide derivative

Herein, we describe a short peptide derivative containing a hydrazone bond showing transient hydrogel formation triggered by hydrazone–oxime exchange reaction.