Academic plagiarism has remained a major concern for higher education institutions, as it hampers not only the quality of the teaching-learning process and research, but also the overall educational institution. This issue appears to be even more serious in online and distance education institutions. As a result, a qualitative study was conducted on an online university in Pakistan to investigate the determinants of academic plagiarism and to find ways to address this issue. The students were given an open-ended questionnaire to reflect their opinions on the awareness and understanding of plagiarism, its determinants, and ways to address it. The findings revealed that most of the 267 online university students had a poor awareness and understanding of plagiarism. Major reasons for students’ plagiarism turned out to be a lack of a proactive approach to create awareness, an omission of citation conventions from course content, untrained teachers, a lack of strict penalties and their proper implementation, poor time management, a fear of failure, a lack of confidence, laziness, and a culture of plagiarism. The study proposes the Awareness, Support, and Prevention model (AS&P model) to address this issue in higher education institutions.