Surfactant spreading in a two-dimensional cavity and emergent contact-line singularities

We model the advective Marangoni spreading of insoluble surfactant at the free surface of a viscous fluid that is confined within a two-dimensional rectangular cavity. Interfacial deflections are assumed small, with contact lines pinned to the walls of the cavity, and inertia is neglected. Linearising the surfactant transport equation about the equilibrium state allows a modal decomposition of the dynamics, with eigenvalues corresponding to decay rates of perturbations. Computation of the family of mutually orthogonal two-dimensional eigenfunctions reveals singular flow structures near each contact line, resulting in spatially oscillatory patterns of shear stress and a pressure field that diverges logarithmically. These singularities at a stationary contact line are associated with dynamic compression of the surfactant monolayer. We show how they can be regularised by weak surface diffusion. Their existence highlights the need for careful treatment in computations of unsteady advection-dominated surfactant transport in confined domains.

Research on Flow and Heat Transfer Characteristics of Multiple Impinging Jets on a Moving Conveyor Belt

Turbulent impinging jets at three different jet nozzle forms were numerically analyzed using the SIMPLE algorithm and k-epsilon turbulent model to investigate the flow field and heat transfer characteristics. The food placed upon a moving conveyor belt cooled by series of impinging jets under a specific condition. Three semi-confined domains with different jet nozzles were established, thereby with slot, rectangular, and funnel-shaped nozzles, respectively. Based on computational fluid dynamic (CFD) calculations, distributions of the temperature and wind velocity at four critical cross-sections of domains were compared. The results reveal that the freezing rate of foods mainly relates to temperature and wind velocity. For three semi-confined domains, the impinging jet with slot nozzles produces higher exit wind velocity, lower center temperature, and a better mass flow uniformity than others, which could better improve the heat transfer performance, and could increase the freezing rate of foods.

An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility

Nucleosome turnover concomitant with incorporation of the replication-independent histone variant H3.3 is a hallmark of regulatory regions in the animal genome. Nucleosome turnover is known to be universally linked to DNA accessibility and histone acetylation. In mouse embryonic stem cells, H3.3 is also highly enriched at interstitial heterochromatin, most prominently at intracisternal A-particle endogenous retroviral elements. Interstitial heterochromatin is established over confined domains by the TRIM28-KAP1/SETDB1 corepressor complex and has stereotypical features of repressive chromatin, such as H3K9me3 and recruitment of all HP1 isoforms. Here, we demonstrate that fast histone turnover and H3.3 incorporation is compatible with these hallmarks of heterochromatin. Further, we find that Smarcad1 chromatin remodeler evicts nucleosomes generating accessible DNA. Free DNA is repackaged via DAXX-mediated nucleosome assembly with histone variant H3.3 in this dynamic heterochromatin state. Loss of H3.3 in mouse embryonic stem cells elicits a highly specific opening of interstitial heterochromatin with minimal effects on other silent or active regions of the genome.

Investigation of Statistical Metal-Insulator Transition Properties of Electronic Domains in Spatially Confined VO2 Nanostructure

Functional oxides with strongly correlated electron systems, such as vanadium dioxide, manganite, and so on, show a metal-insulator transition and an insulator-metal transition (MIT and IMT) with a change in conductivity of several orders of magnitude. Since the discovery of phase separation during transition processes, many researchers have been trying to capture a nanoscale electronic domain and investigate its exotic properties. To understand the exotic properties of the nanoscale electronic domain, we studied the MIT and IMT properties for the VO2 electronic domains confined into a 20 nm length scale. The confined domains in VO2 exhibited an intrinsic first-order MIT and IMT with an unusually steep single-step change in the temperature dependent resistivity (R-T) curve. The investigation of the temperature-sweep-rate dependent MIT and IMT properties revealed the statistical transition behavior among the domains. These results are the first demonstration approaching the transition dynamics: the competition between the phase-transition kinetics and experimental temperature-sweep-rate in a nano scale. We proposed a statistical transition model to describe the correlation between the domain behavior and the observable R-T curve, which connect the progression of the MIT and IMT from the macroscopic to microscopic viewpoints.

An embryonic stem cell-specific heterochromatin state allows core histone exchange in the absence of DNA accessibility

ABSTRACTNucleosome turnover concomitant with incorporation of the replication-independent histone variant H3.3 is a hallmark of regulatory regions in the animal genome. In our current understanding, nucleosome turnover is universally linked to DNA accessibility and histone acetylation. In mouse embryonic stem cells, H3.3 is also highly enriched at interstitial heterochromatin, most prominently intracisternal-A particle endogenous retroviral elements. Interstitial heterochromatin is established over confined domains by the TRIM28/SETDB1 corepressor complex and has stereotypical features of repressive chromatin, such as H3K9me3 and recruitment of all HP1 isoforms. Here, we demonstrate that fast histone turnover and H3.3 incorporation is compatible with these hallmarks of heterochromatin. Further, we find that histone H3.3 is required to maintain minimal DNA accessibility in this surprisingly dynamic heterochromatin state. Loss of H3.3 in mouse embryonic stem cells elicits a highly specific opening of interstitial heterochromatin with minimal effects on other silent or active regions of the genome.

Modeling Acoustic Cavitation Using a Pressure-Based Algorithm for Polytropic Fluids

A fully coupled pressure-based algorithm and finite-volume framework for the simulation of the acoustic cavitation of bubbles in polytropic gas-liquid systems is proposed. The algorithm is based on a conservative finite-volume discretization with collocated variable arrangement, in which the discretized governing equations are solved in a single linear system of equations for pressure and velocity. Density is described by the polytropic Noble-Abel stiffened-gas model and the interface between the interacting bulk phases is captured by a state-of-the-art algebraic Volume-of-Fluid (VOF) method. The new numerical algorithm is validated using representative test-cases of the interaction of acoustic waves with the gas-liquid interface as well as pressure-driven bubble dynamics in infinite and confined domains, showing excellent agreement of the results obtained with the proposed algorithm compared to linear acoustic theory, the Gilmore model and high-fidelity experiments.

Prilog koncipiranju nove teorije životnog vijeka

Modern developmental psychology has been characterised with a wealth of empirical facts and a relatively small number of theories, which are mostly oriented to the confined time of development and confined domains of functioning. Because of some important changes in contemporary developmental psychology, according to which it is no more just a theory of child development but the life-span developmental psychology, it is very important to integrate information about different developmental aspects. It should bring into accord analysis with respect to life periods and different behaviors. In a new developmental theory attention should be directed to the personal contribution to one's own development and the self-regulation of the development. The theory of personal development which is proposed by Heckhausen and Schultz (1995)includes primary and secondary control of development. On the basis of some empirical indications it should be proposed that the new theory has to include tertiary control as well. The tertiray control of development is neglected probably because it includes some more mature personality defense mechanisms. Developmental self-regulation could be reached through connection of outer demands (biological and social) with the efforts of each person in accordance to primary, secondary and tertiary control.