Analytical Research of Integrity Testing on Bore Pile

The integrity test is conducted on RCC bore pile this test is conducted as per the guidelines of ASTM D5882 respectively. This test is conducted on “Perstorp site which is located in dis -Bharuch Gujrat. In this region the Strata of soil is soft aquifer hence to carry heavy structural load, pile foundation is best solution. The experimental study is carries out on 20 meter length of Bore pile of 600mm in diameter. This paper is based on experimental study on bore pile due to assess the pile integrity for potential problem like cross section change, honeycombing, concrete quality, continuity etc.

Integrity performance assessment of a Closed System Transfer Device syringe adaptor as a terminal closure for Luer-Lock syringes.

Objectives To investigate the container closure integrity of a Closed System Transfer Device syringe adaptor lock in combination with disposable Luer-Lock syringes as the terminal closure device. The UK NHS Pharmaceutical Quality Assurance committee requires syringe integrity data for final storage devices of aseptic products such as chemotherapy drugs when prepared in advance and stored prior to use as is standard practice for dose banded drugs. The assessment comprised both physical and microbial integrity testing of the combination closed system/ Luer-Lock syringes containers at syringe sizes: 1mL, 20mL, and 50mL. Methods Integrity testing was performed as described in the NHS Pharmaceutical Quality Assurance Committee Yellow Cover Document 2nd edition 2013 with ChemfortTM (Simplivia, IL) syringe adaptor lock devices as replacement for sterile blind hubs. Microbiological integrity was assessed according to Method 1 part 1.4 using Brevundimonas diminuta at 32oC for up to 14-days contact time. Physical integrity was assessed using Method 3 of the yellow cover document which is a dye intrusion method. Dye intrusion was assessed both visually and using a validated ultraviolet-visible spectrophotometer method. Results ChemfortTM syringe adaptor lock/ Luer-Lock syringe combinations were shown to be: (1) free of microbiological contamination after 14-days contact time, (2) free of dye intrusion at all syringe sizes tested (n=61 in total). The data demonstrates 100% closure integrity of the final container system when ChemfortTM syringe adaptor lock replaces the syringe hub as the terminal closure device. Conclusions Syringe adaptor lock components complied with the NHS Pharmaceutical Quality Assurance Committee Yellow Cover Document syringe integrity requirements when used as the terminal closure of Luer-Lock disposable syringes from 1mL up to 50mL. Therefore, syringe adaptor lock (ChemfortTM) can be used as the terminal closure system for pre-filled syringes of chemotherapeutic drug products prepared in advance in UK NHS Pharmaceutical Technical Services.

Procedure for authorization of professional integrity testing and assessment of the result of professional ingritacy test

In this article analyzed the procedure for authorizing the testing of professional integrity and the assessment of the result of the test of professional integrity regulated in XXXIV of the Code of Civil Procedure of the Republic of Moldova. All the procedural conditions in which this procedure takes place are investigated. Particular attention was given to the analysis of the means offered by the procedural law to the court to ascertain circumstances in order to achieve the purpose of this procedure - authorizing the testing of professional integrity and assessing the result of the professional ingratitude test.