Review on Nidanas of Medoroga

Today most of the people are obsessed with loosing weight. Obesity is defined as the condition where one is at least 20% more than the ideal bodyweight. Obesity is caused by a sedentary lifestyle, lack of physical activity, an irregular diet and sleep pattern and stress. Everybody is busy and living a stressful life. As a result of growing challenges of modernization, man has responded by readjust in his customary behavior. He has tried successfully to maximize his intellectual and physical capabilities for deriving highest amount of productivity. Man has adapted himself to the fast-paced by modifying his dietary and lifestyle preference to suit the modern era.

Blood albumin as a prognostic factor among unselected medically treated inpatients

Aim: The aim of this study is to determine the prognostic value of blood albumin (BA) in an unselected population of inpatients. Materials & methods: We performed prospective analysis of the medical documentation of 7279 patients hospitalized between July 2014 and September 2017. Results: Individuals with BA ≥3.35 mg/dl had significantly lower risk of in-hospital death (odds ratio [OR]: 0.22; 95% CI: 0.19–0.27; p < 0.001) and 14-day readmission (OR: 0.64; 95% CI: 0.55–0.77; p < 0.0001). BA concentration was the strongest favorable factor predicting inpatient survival in a Cox hazard regression model (OR: 0.43; 95% CI: 0.36–0.50; p < 0.001), did not correlate with body mass index and actual-to-ideal bodyweight ratio and was strongly affected by numerous non-nutrient factors. Conclusion: BA concentration showed similar or better predictive and diagnostic power in relation to all-cause in-hospital mortality and 14-day readmission among inpatients than selected multifactorial scores.

Physical activity in prevention and reduction of cardiovascular risk

Introduction There is evidence that physical activity decreases the degree of atherosclerosis in the coronary arteries in persons who are physically active by modifying the chemistry and metabolism of lipoproteins. The effect of physical activity on the lipid status is achieved by affecting the enzymes of lipoprotein metabolism including the lipoprotein and liver lipase and transport protein of cholesterol esters. Epidemiological investigations on the effect of physical activity in prevention of cardiovascular diseases point to the fact that the persons who have a higher degree of cardio-respiratory endurance have a much lower mortality rate than those with a lower degree. The positive effect of physical activity on the cardiovascular system is reflected on the improved aerobic capacity, metabolic function, amplification of lipid profile, insulin sensitivity, immunological functions; it increases the perfusion of myocardium and the fibrinolytic activity, and reduces the adherence of thrombocytes due to increased synthesis of prostaglandin (PGI2), it also enhances the energy consumption, which is important in the maintenance of ideal bodyweight, prevention and treatment of obesity, and it has a positive effect on the control of stress. Conclusion With respect to the effects on the lipid status, aerobic physical exercises like running, swimming, cycling, with the intensity of training of a medium (65% VO2) load, have a positive effect on lipid status. The best form of physical activity is the one in which the endurance and power are increased.