The Effect Of Breathing Relaxation And Lavender Aromatherapy On Insomnia In The Elderly

Background: The elderly experience insomnia in the form of problems with symptoms of sleep disorders in the form of repeated difficulties in sleeping or maintaining sleep even though there is an opportunity to sleep. The objective of research was to analyze the effect of Breathing Relaxation Aromatherapy Combination Lavandula Angustifolia on Insomnia in the Elderly. Methods: The design was a pre-experiment with approach the one group pretest-posttest design. The research population was elderly insomnia in elderly Posyandu and the sample was 21 peoples. The sampling research was total sampling. Variabel independent was Breathing Relaxation combination with lavender aromatherapy is relaxation using breathing techniques slowly and deeply, variabel dependen was insomnia level. Statistic test use Wilcoxon Signed Ranks Test Results: The results showed that The Wilcoxon Signed Ranks Test ρ value = 0,000, H1 is accepted, meaning that there is an effect of the Breathing Relaxation and lavender aromatherapy on insomnia in the elderly. The combination of Breathing Relaxation and lavender aromatherapy increases the relaxation response in the elderly. Conclusion: Effect of Breathing Relaxation combination of lavender aromatherapy (Lavandula angustifolia) is more effective in reducing insomnia levels in the elderly and is highly recommended and safe for the elderly)

Korelasi kadar hepcidin dan asupan makanan dengan serum transferrin reseptor dan hemoglobin pada remaja stunted overweight

Background: Stunted overweight is associated with mild chronic inflammation. The state of inflammation will increase the expression of hepcidin, which affects the iron status of the body, besides the intake of protein, iron, and vitamin C.Objective: To analyze the correlation of hepcidin levels and food intake (protein, iron, vitamin C) with serum transferrin receptors (sTfR) and hemoglobin in stunted overweight adolescents.Method: The design of research was cross-sectional. The subjects were 64 adolescents stunted overweight aged 15-18 years in four high/vocational schools in the Banyumanik District, Semarang City. Measurement the level of hepcidin and sTfR was using the ELISA method and haemoglobin was using Cyanomethemoglobin method. Data on protein, iron, vitamin C intake was using the SQ-FFQ method. Bivariate analysis was using Pearson and Spearman correlation test then followed by multiple linear regression analysis.Results: The result showed that 89.1% subjects had adequate intake of protein, 54.7% subjects had low intake of vitamin C, 76.6% subjects had low intake of iron. Hepcidin levels in all subjects were 100% normal. There were 7.8% subjects with a low sTfR and 7.8% with a low haemoglobin level. Statistic test showed there was correlation between hepcidin with haemoglobin and sTfR (p1 = 0,010 r1 = -0,319, p2 = 0,001, r2 = 0,569). From food intake, only intake iron was correlated with haemoglobin but not with sTfR. There was significant difference between the mean of haemoglobin and sTfR among girls and boys. Further analysis, showed that only hepcidin was a weak negative determinant for sTfR (R2 = 0,120). The determinant factors for haemoglobin were gender (p=0,001) and hepcidin (p =0,004) with the value of R2 = 0,577.Conclusion: Hepcidin correlated with sTfR and haemoglobin while iron intake only correlated with hemoglobin.

A population-level statistic for assessing Mendelian behavior of genotyping-by-sequencing data from highly duplicated genomes

Given the economic and environmental importance of allopolyploids and other species with highly duplicated genomes, there is a need for accurate genotyping methodology that distinguishes paralogs in order to yield Mendelian markers. Methods such as comparing observed and expected heterozygosity are frequently used for identifying collapsed paralogs, but have limitations in genotyping-by-sequencing datasets, in which observed heterozygosity is difficult to estimate due to undersampling of alleles. These limitations are especially pronounced when the species is highly heterozygous or the expected inheritance is polysomic. We introduce a novel statistic, Hind/HE, that uses the probability of sampling reads of two different alleles at a sample*locus, instead of observed heterozygosity. The expected value of Hind/HE is the same across all loci in a dataset, regardless of read depth or allele frequency. In contrast to methods based on observed heterozygosity, it can be estimated and used for filtering loci prior to genotype calling. We also introduce an algorithm that can choose among multiple alignment locations for a given sequence tag in order to optimize the value of Hind/HE for each locus, correcting alignment errors that frequently occur in highly duplicated genomes. Our methodology is implemented in polyRAD v1.2, available at https://github.com/lvclark/polyRAD.

Statistical limitations on drawing inferences about proportional recovery

BackgroundNumerous studies have found large statistical relationships between the amount of recovery and initial impairments in people with stroke. When change scores are regressed onto initial impairments, the resulting slope is approximately ≈0.7for a variety of outcomes. These findings have led to the 70% “proportional recovery rule” and the argument that proportional recovery represents a biological phenomenon. Previous studies of proportional recovery are confounded by statistical limitations that come from regressing change scores onto initial impairments in bounded scales.ObjectiveOur goal is to show that data claimed as evidence for proportional recovery are generally consistent with random patterns of recovery, once statistical limitations are taken into account.MethodsUsing a pooled dataset of N = 373 Fugl-Meyer Assessment (FMA) upper extremity scores extracted from published literature, we ran simulations to illustrate three main arguments: (1) Mathematical coupling renders the traditional null-hypothesis significance test irrelevant in proportional recovery studies; (2) Proportional recovery is one of many alternative hypotheses; (3) Current evidence claimed in favor of proportional recovery is consistent with uniform random recovery.ResultsOur simulations show that if all data were included (no exclusion of “non-fitters”) regressing change scores onto initial impairments in a bounded scale would lead to a slope of ≈ 0.5. Similarly, cluster analysis will spuriously identify groups of fitters and non-fitters, leading to a slope for the fitters of ≈ 0.7, when the underlying recovery is random.ConclusionsThese results cast doubt on the validity of “proportional recovery” as a population level-statistic and a biological phenomenon.

Estudio comparativo de la actitud hacia la estadística en estudiantes de administración de una universidad privada de Lima Este, 2016

El propósito de este estudio consistió en reportar los resultados de la aplicación de la escala de actitud hacia la estadística (EAE) a una muestra no aleatoria de 92 estudiantes de la Escuela Profesional de administración de una universidad privada de Lima Este correspondiente a los turnos mañana, tarde y noche, en relación a las siguientes dimensiones; valor que le dan a la estadística, nivel de dificultad percibida, el afecto hacia la estadística y la competencia cognitiva de los estudiantes, que cursaban la materia de estadística. Alrededor de un 60% manifiestan una actitud favorable o muy favorable hacia la estadística y solo un 4.3% desfavorable. No se encontraron diferencias significativas en el puntaje total de la escala de los estudiantes de esta muestra en función del turno de estudio: mañana, tarde y noche. ABSTRACT The purpose of this research lies in to report the results of Attitude Scale Application to (EAE) Random Sample Statistic of 92 students of Business School from Lima private university corresponding to morning, afternoon and evening shifts respect to the following dimensions: Statistic value, Perceived difficulty level, Statistic Affection, Cognitive Competence Stastistic Students. Around 60% show favorable attitude to statistic course but not 4.3%. There is no meaningful differences in the Students Scale Final Results who attend in morning, afternoon and evening shifts.

Influence of Chemical Disorder, Magnetic Field and Phason Flipd on the Localization of Electronic States in a Regular Icosahedral Quasicrystal

The influence of substitutional chemical disorder, magenetic field and phasons, on the electronic spectrum and wave functions of icosahedral quasicrystals is investigated by means of tight-biding approximation and level statistic method. The results show that the localization of electronic states in an ideal quasictystal exists due to their coherent interfernce at the Fremi level which is caused by the symmetry and aperiodic long-range order.