multiway data analysis
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2022 ◽  
Vol 23 (1) ◽  
Author(s):  
Lu Li ◽  
Huub Hoefsloot ◽  
Albert A. de Graaf ◽  
Evrim Acar ◽  
Age K. Smilde

Abstract Background Analysis of dynamic metabolomics data holds the promise to improve our understanding of underlying mechanisms in metabolism. For example, it may detect changes in metabolism due to the onset of a disease. Dynamic or time-resolved metabolomics data can be arranged as a three-way array with entries organized according to a subjects mode, a metabolites mode and a time mode. While such time-evolving multiway data sets are increasingly collected, revealing the underlying mechanisms and their dynamics from such data remains challenging. For such data, one of the complexities is the presence of a superposition of several sources of variation: induced variation (due to experimental conditions or inborn errors), individual variation, and measurement error. Multiway data analysis (also known as tensor factorizations) has been successfully used in data mining to find the underlying patterns in multiway data. To explore the performance of multiway data analysis methods in terms of revealing the underlying mechanisms in dynamic metabolomics data, simulated data with known ground truth can be studied. Results We focus on simulated data arising from different dynamic models of increasing complexity, i.e., a simple linear system, a yeast glycolysis model, and a human cholesterol model. We generate data with induced variation as well as individual variation. Systematic experiments are performed to demonstrate the advantages and limitations of multiway data analysis in analyzing such dynamic metabolomics data and their capacity to disentangle the different sources of variations. We choose to use simulations since we want to understand the capability of multiway data analysis methods which is facilitated by knowing the ground truth. Conclusion Our numerical experiments demonstrate that despite the increasing complexity of the studied dynamic metabolic models, tensor factorization methods CANDECOMP/PARAFAC(CP) and Parallel Profiles with Linear Dependences (Paralind) can disentangle the sources of variations and thereby reveal the underlying mechanisms and their dynamics.


2021 ◽  
Vol 13 (23) ◽  
pp. 13073
Author(s):  
Edith Johana Medina-Hernández ◽  
María José Fernández-Gómez ◽  
Inmaculada Barrera-Mellado

The aim of this article was to study 23 time use activities measured in the two latest Colombian National Time Use Surveys, taken in 2013 (with 119,899 participants over the age of 10) and in 2017 (with a sample of 122,620 participants), to identify similarities and differences between the years of the survey by gender, age group, and socioeconomic level. The study’s results were obtained using the CO-STATIS multiway multivariate data analysis technique, which is comprised of two X-STATIS analyses and co-inertia analysis. The results confirm the existence of gender issues related to time use in Colombia, which are associated with gender stereotypes that link women to unpaid work and home care, especially in low socioeconomic levels, where women face limitations in terms of the time available to earn their own income. Additionally, differences were found by socioeconomic level, where Colombians of high socioeconomic status in all age groups are able to devote more time to leisure and recreational activities.


2021 ◽  
Author(s):  
Lu Li ◽  
Huub Hoefsloot ◽  
Albert A. Graaf ◽  
Evrim Acar ◽  
Age K. Smilde

Abstract Background: Analysis of dynamic metabolomics data holds the promise to improve our understanding of underlying mechanisms in metabolism. For example, it may detect changes in metabolism due to the onset of a disease. Dynamic or time-resolved metabolomics data can be arranged as a three-way array with entries organized according to a subjects mode, a metabolites mode and a time mode. While such time-evolving multiway data sets are increasingly collected, revealing the underlying mechanisms and their dynamics from such data remains challenging. For such data, one of the complexities is the presence of a superposition of several sources of variation: induced variation (due to experimental conditions or inborn errors), individual variation, and measurement error. Multiway data analysis (also known as tensor factorizations) has been successfully used in data mining to find the underlying patterns in multiway data. In this paper, we study the use of multiway data analysis to reveal the underlying patterns and dynamics in time-resolved metabolomics data. Results: We focus on simulated data arising from different dynamic models of increasing complexity, i.e., a simple linear system, a yeast glycolysis model, and a human cholesterol model. We generate data with induced variation as well as individual variation. Systematic experiments are performed to demonstrate the advantages and limitations of multiway data analysis in analyzing such dynamic metabolomics data and their capacity to disentangle the different sources of variations. We choose to use simulations since we want to understand the capability of multiway data analysis methods which is facilitated by knowing the ground truth. Conclusion: Our numerical experiments demonstrate that despite the increasing complexity of the studied dynamic metabolic models, tensor factorization methods CANDECOMP/PARAFAC(CP) and Parallel Profiles with Linear Dependences (Paralind) can disentangle the sources of variations and thereby reveal the underlying mechanisms and their dynamics.


2021 ◽  
Vol 50 (2) ◽  
pp. 205-215
Author(s):  
А.Ya. Rubinstein ◽  
◽  
N.A. Burakov ◽  

The paper discusses the ranking of journals based on the alternative to Scientometrics, where the basic unit of information is not the citation rate of publications, but their qualitative characteristics, obtained on the basis of the regular sociological survey of the economists’ community conducted by the “Journal of NEA” in 2020. The empirical data obtained made it possible to determine the size of the audience of each journal. The paper shows that the size of the journals’ readership has a direct impact on the respondents’ assessments of the quality of publications and scientific authority of the journals. The ranking of economics journals by each particular criterion — “Interest in Journal Publications”, “Scientific Level of Journals” and “Public Prestige of Journals” is presented. Use of the “Multiway data analysis” methodology has provided measurement not only of particular criteria that reflect hidden relations between their characteristics, but also determined the weight function of their aggregation in the aggregate ranking of journals — the “Ranking-2020”. The article also contains a comparative analysis of ranking the journals on the basis of the “Rating-2020” and re-rating of the RSCI and criticizes RSCI criteria “Science Index” and “Public Examination”.


Luminescence ◽  
2020 ◽  
Vol 35 (3) ◽  
pp. 385-392
Author(s):  
Saeed Bagheri ◽  
Mohsen Kompany‐Zareh ◽  
Touraj Karimpour

2019 ◽  
Vol 23 (2) ◽  
pp. 660-671 ◽  
Author(s):  
Yissel Rodriguez Aldana ◽  
Borbala Hunyadi ◽  
Enrique J. Maranon Reyes ◽  
Valia Rodriguez Rodriguez ◽  
Sabine Van Huffel

2018 ◽  
Vol 10 (6) ◽  
pp. 1051-1061 ◽  
Author(s):  
Bin Liu ◽  
Lirong He ◽  
Yingming Li ◽  
Shandian Zhe ◽  
Zenglin Xu

Author(s):  
Yissel Rodriguez Aldana ◽  
Borbala Hunyadi ◽  
Enrique J. Maranon Reyes ◽  
Valia Rodriguez Rodriguez ◽  
Sabine Van Huffel

2015 ◽  
Vol 3 (1) ◽  
pp. 18-36 ◽  
Author(s):  
GIANCARLO RAGOZINI ◽  
DOMENICO DE STEFANO ◽  
MARIA ROSARIA D'ESPOSITO

AbstractMost social networks present complex structures. They can be both multi-modal and multi-relational. In addition, each relationship can be observed across time occasions. Relational data observed in such conditions can be organized into multidimensional arrays and statistical methods from the theory of multiway data analysis may be exploited to reveal the underlying data structure. In this paper, we adopt an exploratory data analysis point of view, and we present a procedure based on multiple factor analysis and multiple correspondence analysis to deal with time-varying two-mode networks. This procedure allows us to create static displays in order to explore network evolutions and to visually analyze the degree of similarity of actor/event network profiles over time while preserving the different statuses of the two modes.


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