Standardization of Starch Concentration for Saree Rolling at Domestic Usage

Starching is one of the most significant finish given to sarees. Apart from minimizing wrinkles, starch/sizing material protects fiber due to its polished appearance provided by adequate starch concentrations while finishing the textile material. Hence, the present study is conducted on standardization or optimization of selected starches (Mango kernel starch (MKS), Jack fruit seed (JFS) starch, Bhagavathi gum (BG)/synthetic gum, Maize starch (MS) and Revive liquid (RL)) for 1 and 3 percent concentrations as per the consumer requirement on cotton fabric. All the sized samples were tested for stiffness, crease recovery angle, and tear strength parameters assessing against control sample. Results showed that, for all the tested samples, the crease recovery angle of control sample is more in both ways and other treated samples have higher angle in warp ways than the weft ways. It was also observed, with an increase in concentration there was an increase in the angle. Similarly, the bending length and tear strength is more towards warp direction than weft direction in all the tested samples. Bending length is higher in 3 percent than 1 percent starch concentration for both warp. Amongst all the starched samples, MSK has good tear strength in both directions of the fabric. Based on the study it can be concluded that, depend on the type of the material one and three per cent of the starches from natural sources can be efficiently used at domestic level.

Biocatalyst: Phytase Production in Solid State Fermentation by OVAT Strategy

The phytase-producing Pichia membranifaciens S3 (MG663581) was isolated from sugarcane juice using phytase screening medium. The predicted and experimental model showed maximum phytase production of 364 U/ml appearing g/100ml: Jack fruit seed (1.5), peptone (0.15), dextrose (0.50), yeast extract (0.05), malt extract (0.05) pH 5.5 and 280C) used OVAT strategy by Solid state fermentation through shake flask methodology. The modelling, 3D structure of Phy S3 amino acid sequences was modelled (PhyS3.B99990003) by using Modeler 9.23 and validated results showed that 86.4% in the favoured region by Ramachandran plot.

FORMULATION AND EVALUATION OF TELMISARTAN FAST DISSOLVING TABLETS USING JACK FRUIT SEED STARCH AS SUPERDISINTEGRANT

Objective: The main objective of the current study is to enhance the solubility of Biopharmaceutical Classification System (BCS) Class-II drug Telmisartan using jack fruit seed starch as super disintegrant which increases drug release. Methods: Starches were extracted using alkali technique using sodium hydroxide at 0.1%, 0.25%, and 0.5% concentrations and water from Jack fruit seed powder. These starches were evaluated for various phytochemical and physicochemical tests. Fast dissolving tablets were prepared using Telmisartan, jack fruit seed starch and Croscarmellose sodium in various concentrations using wet granulation technique. Various pre and post-compression parameters were evaluated along with in vitro drug release studies, characterization studies like Fourier Transform Infra-Red spectroscopy (FTIR), Differential Scanning Calorimetry (DSC), Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD) and accelerated stability studies. Results: Phytochemical tests revealed the presence of only starch in all the extracts. The starch prepared from 0.1% sodium hydroxide (JFS2) showed best physicochemical properties. From in vitro dissolution studies, it was observed that formulations F5 and F11 containing 15% w/w of JFS2 and 15% w/w of croscarmellose sodium showed faster disintegration and increased dissolution rate compared with other formulations. FTIR and DSC studies showed that there were no major interactions among drug and excipients. XRD studies revealed the nature of formulations. Accelerated stability studies revealed the stability of tablets. Conclusion: Thus, the tablets prepared using Jack fruit seed starch revealed the super disintegrant property of starch.

FORMULATION AND EVALUATION OF DOLUTEGRAVIR SODIUM SOLID DISPERSIONS AND FAST DISSOLVING TABLETS USING POLOXAMER-188 AND JACK FRUIT SEED STARCH AS EXCIPIENTS

Objective: The current work mainly focuses on solubility enhancement of dolutegravir which is a biopharmaceutical classification system Class-II drug using jack fruit seed starch (JFS2) as excipient which improves the drug release. Materials and Methods: Starches were extracted using aqueous and alkali methods (sodium hydroxide at 0.1%, 0.25%, and 0.5% concentrations) from jack fruit seed powder. These starches were evaluated for phytochemical and physicochemical parameters. Fast dissolving tablets were prepared using dolutegravir sodium solid dispersion, JFS2, and croscarmellose sodium (CCS) in various concentrations using wet granulation technique. Various pre- and post-compression parameters were evaluated along with in vitro drug release studies; characterization studies such as Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC), scanning electron microscopy, X-ray diffraction (XRD), and stability studies. Results: Phytochemical tests revealed the presence of only starch in all extracts. Starch prepared from 0.1% sodium hydroxide (JFS2) showed best physicochemical properties. From in vitro dissolution studies, it was observed that solid dispersion formulation DF3 containing dolutegravir sodium and poloxamer-188 in 1:1.5 ratios showed a better dissolution rate. From in vitro dissolution studies, tablet formulations DFT6 and DFT9 containing 12.5% w/w of JFS2 and 12.5% w/w of CCS showed enhanced dissolution rate compared with other formulations. FTIR and DSC studies revealed that there were no major interactions between drug and excipients. XRD studies revealed the nature of formulations. Accelerated stability studies showed that all tablets were stable. Conclusion: The tablets prepared using jack fruit starch seed starch revealed the superdisintegrant property of starch.

Storage stability of encapsulated anthocyanin-rich extract from black carrot (Daucus carota ssp. Sativus) using different coating materials

The enzymatic assisted cum hydraulic pressed extract of black carrot which has high anthocyanin content were encapsulated through spray drier using a mixture of Jack fruit seed starch, Soy protein and NBRE-15 (SET -1) and in the second set of experiment using Jack fruit seed starch, Whey protein and NBRE-15 (SET-2) as coating materials. The quality attributes of the powders which were produced at an optimum mixture of SET -1 and SET-2 were characterized by anthocyanin content, antioxidant capacity and L*, a*, b*, C and Hº value. It was reported that SET-1 was found better-encapsulating material as compared to SET-2. SET-1 had higher retention of anthocyanin content, colour, antioxidant activity during storage at 25 ºC.

Physiology and postharvest conservation of ‘Paluma’ guava under coatings using Jack fruit seed-based starch

The aim of this work was to evaluate the effect of jackfruit seed starch-based (S) coatings, added to chitosan and alginate on the physiology and maintenance of quality of cold stored ‘Paluma’ guavas, followed by transfer to the room condition. The design was the completely randomized, in a 4x2 factorial scheme, in 4 replications, with 4 coatings (dispersion of S - 4%; S 2% + chitosan - 2% (SC); S - 2% + alginate - 2% (SA); and the uncoated control), in 2 environments (refrigerated (10±2 °C e 80±2% RH) with transfer to room condition (25±3 °C e 75±4% HR)), on the 16th and 20th day of cold storage. The SC and SA coatings were efficient in reducing the respiratory rate in fruits during 10 days at room condition. The SC coating delayed fruit ripening, and maintained firmness and color, with intention of purchasing and appearance higher than the limit of acceptance for another 6 days, following transferring to room condition, at the 16th day of refrigeration.