We examine the lived experiences of high-school students who participatedin lesbian, gay, bisexual, transgender, and queer (LGBTQ)-centered activismof some kind, highlighting the promise of gay-straight alliance groups bycomparing the experiences of students at schools with gay-straightalliances (GSA schools) with the experiences of students at schools thatdid not have an LGBTQ-specific group (no-GSA schools). We compare studentsat GSA and no-GSA schools based on their experiences of harassment,experiences of support from authority figures, and patterns of friendships.We find that students at both types of schools experienced harassment andheard negative comments about lesbian and gay people. However, students atGSA schools reported more support from teachers and administrators thanstudents at no-GSA schools, who have stories of teachers and administratorsactively opposing equality for LGBTQ people. Students at GSA schoolsreported a wide variety of friendships across sexual identities, whilestudents at no-GSA schools felt more isolated and withdrawn. Thismuch-needed qualitative comparative analysis of students’ experiencesbrings a human face to the improved quality of life that schools withgay-straight alliances can bring to young people.