What Dreams May Come

What dreams may come is a piece of ethnofiction that tells the story of a young girl and her grandmother, displaced by the climate crisis and conflict. The story centres on the strong, abiding relationship between the girl and her grandmother. Their relationship is the anchor point for their survival in the new unhappy world that they find themselves in. As an anthropologist of displacement, this short story is an attempt to tell the story of climate crisis, displacement and conflict through a fictional lens, a place where fable and reality coincide and collide.

Research on Ultra-Wideband (UWB) Accurate Positioning under Signal Interference Based on Deep Learning

UWB (Ultra-Wideband) technology is also called "Ultra-Wideband", also known as pulse radio technology. UWB-based positioning technology has real-time indoor and outdoor accurate tracking capabilities, with high positioning accuracy, which can achieve centimeter-level or even millimeter-level positioning. Based on the provided anchor point ranging information, this paper analyzes normal and abnormal data and establishes an accurate positioning model. For task 1, preprocess the data, export the file, delete invalid data, and fill in missing values. For task 2, it is required to establish models for normal and abnormal data respectively. For task 3, it is consistent with the model obtained in task 2. The only difference is that the coordinates of the four anchor points used for the test data have changed. When the target coordinates are calculated, the anchor point coordinates can be replaced to obtain the model required by task 3. For task 4, use the processed data in task one to establish a mathematical model, and train the model through the integrated learning method to determine whether the collected signal is interference. For task 5, first use the integrated learning model in task four to eliminate the interference data in the data, import the eliminated data into the positioning model of task two for positioning, and add Kalman based on interference recognition to the static estimation algorithm.

Ingredients of empire: An oceanic approach to the study of Dutch imperialism and its aftermath

This article turns to the figure of the ship in the controversial Dutch Sinterklaas celebration to explore what an oceanic framework might bring to the study of Dutch imperialism, colonialism, and slavery. Drawing on what Renisa Mawani calls an ‘oceanic approach and method’ for the study of colonial history, law, and colonial–racial orders, I examine the ship as an anchor point for abstracting, enacting, and rehearsing a colonial–racial order that emerged during the highpoint of Dutch imperialism and continues to permeate the national imaginary at present. Looking at how a Dutch ‘maritime imagination’ conditions imperial fantasies and desires, this article is an exercise in developing what I call a ‘cultural oceanography’ of Dutch imperialism and its aftermath.

Analysis of Injury Potential of Three-year-old Child Occupants Caused by Inappropriate Installation of Enhanced Child Restraint System with Top Tether in Frontal Crash Accidents

Objective: Frontal crash accidents remain a significant factor in causing the preventable injury and fatality for child occupants aged 3 in China. Despite the increased public awareness and utilization of child restraint system (CRS), inappropriate installations still exist and lead to a potential to result in injuries of head, thorax and abdomen regions of child occupants, especially when it comes to enhanced child restraint system (ECRS) with top tether. The current study focuses on the influence of top tether upon safety performance of ECRS with top tether in dynamic tests with different set-ups and explores the relationship between inappropriate installation of ECRS with top tether and the injury potential of child occupants aged 3 in a frontal crash. Methods: A testing scheme including 4 dynamic tests was devised to ascertain the extent to which the top tether affected the accelerations of thorax, the abdominal penetration and the head displacements. Different kinds of acceleration curves were employed to conduct the tests and to simulate the real status and situation of child occupants aged 3 in the CRS installed with top tether and without top tether respectively. Parameters of accelerations, abdominal penetrations, and head displacements were measured to analyze quantitatively the influence of inappropriate installations of ECRS with top tether under different conditions. Results: The safety performance of ECRS with the use of top tether was found better than that of ECRS without the use of top tether either in the normal condition or in the extreme condition. The test using the acceleration curves defined by regulations, the accelerations of thorax, abdominal penetrations, and head displacements of P3 manikin in the ECRS with the top tether connected to the anchor point revealed results that all met the requirements. While in the test using acceleration curves of the same kind, and when the top tether was not connected, the parameters measured displayed that the safety performance of the sample was worse than the former one. As for the tests using the more severe acceleration curves defined at will, it was more obvious that top tether could affect the function and safety performance of ECRS greatly, and the functional failure and severe damages occurred to the ECRS without the use of top tether. ECRS with the use of top tether was partly qualified even under the more severe conditions. Conclusions: Inappropriate installation of ECRS such as omitting the step of connecting top tether to anchor point could cause severe injuries and fatalities in frontal crash accidents. Effective measures should be taken to minimize the chances of inappropriate installations of ECRS.

Expression patterns of signalling molecules and transcription factors in the early rabbit embryo and their significance for modelling amniote axis formation

The anterior-posterior axis is a central element of the body plan and, during amniote gastrulation, forms through several transient domains with specific morphogenetic activities. In the chick, experimentally proven activity of signalling molecules and transcription factors lead to the concept of a ‘global positioning system’ for initial axis formation whereas in the (mammotypical) rabbit embryo, a series of morphological or molecular domains are part of a putative ‘three-anchor-point model’. Because circular expression patterns of genes involved in axis formation exist in both amniote groups prior to, and during, gastrulation and may thus be suited to reconcile these models, the expression patterns of selected genes known in the chick, namely the ones coding for the transcription factors eomes and tbx6, the signalling molecule wnt3 and the wnt inhibitor pkdcc, were analysed in the rabbit embryonic disc using in situ hybridisation and placing emphasis on their germ layer location. Peripheral wnt3 and eomes expression in all layers is found initially to be complementary to central pkdcc expression in the hypoblast during early axis formation. Pkdcc then appears — together with a posterior-anterior gradient in wnt3 and eomes domains — in the epiblast posteriorly before the emerging primitive streak is marked by pkdcc and tbx6 at its anterior and posterior extremities, respectively. Conserved circular expression patterns deduced from some of this data may point to shared mechanisms in amniote axis formation while the reshaping of localised gene expression patterns is discussed as part of the ‘three-anchor-point model’ for establishing the mammalian body plan.

Abstract P-36: Structural Analysis of Conformational Changes of Bacterial and Eukaryotic Tubulins

Background: Eukaryotic α- and β-tubulin proteins stand out among tubulin-like proteins by their ability to form hollow dynamically unstable microtubules (MT) with 13 protofilaments. Microtubules are part of the cell cytoskeleton and play a key role in chromosome division in mitosis. A considerable amount of anticancer drugs works on microtubules level breaking its dynamic. But the mechanism of dynamic instability and works of these drugs remains unknown. Bacteria of the genus Prostecobacter have unique bacterial tubulins (BtubA/B) capable to form hollow dynamically unstable 5 protofilament MTs (miniMT). Instead of great differences, both tubulins have many common features. Eukaryotic tubulin was known to have structural changes through GTP hydrolysis (compactization for approximately 2 Å and a twist for 0,1˚). «Anchor point» structure in alpha-tubulin was noticed to be a fixed point in this movement. Methods: We performed comparative structural analysis of BtubA/B and α- and β-tubulin proteins using USCF Chimera10 and MEGA X software. This data was obtained due to a comparison of 3 structures of microtubules with different nucleotides [pdb6DPU, 6DPV, 6DPW] and two structures for bacterial tubulins (miniMT [pdb5o09] and BtubA/B-dimer [pdb2BTQ]). Results: We noticed that bacterial tubulins form shorter protofilaments in miniMT than eukaryotic ones. It can be explained as compaction in two sites instead of one site in eukaryotic MT. Also, the most motionless point of min MT turned out the same "anchor point." Phylogenetic analysis showed that this structure is very conservative in these orthologs. Moreover, the final state of both tubulins (GDP) repeats each other. Conclusion: Our results suggest that bacterial tubulin can have movements through GTP hydrolysis similar to eukaryotic one. And it means that despite different amino acid sequences, bacterial and eukaryotic tubulins have similar keys structures for dynamic instability.

Synchronizing Rock Clocks in the Cambrian

<p>Profound environmental and biological changes took place during the Cambrian, yet, compared to other Phanerozoic intervals, the Cambrian time framework remains poorly constrained, which severely hinders a detailed understanding of the timing and progression of these major geological events. In this study, we report a radiometrically anchored astrochronologic framework across the late Cambrian interval, using high-resolution aluminum (Al) series (1 mm resolution) through the Alum Shale Formation in Scania, southernmost Sweden, based on the fully cored Albjära-1 well. Significant cycles with periods of 405 kyr (long eccentricity), 108 kyr (short eccentricity), 30.4 kyr (obliquity) and 18.8 kyr (precession), associated with long-term amplitude modulation of obliquity and precession, confirmed the orbital imprint on late Cambrian climate. Using the U-Pb dating at 486.78±0.53Ma for the Cambro-Ordovician boundary as anchor point, our timescale spans from ~483.9 to ~500.0 Ma, covering 7 trilobite superzones and 3 graptolite zones. The calibration indicates ages of 491.2±0.54 Ma, 493.9±0.67 Ma, 497.3±0.67 Ma and 500.4±0.67 Ma for the lower boundaries of provisional Stage10, Jiangshanian, Paibian and Guzhangian stages, respectively. This radiometrically anchored astrochronology also provides precise age constrains on regional superzones or even biozones within Scandinavia, and hopefully pave the way for better understanding the late Cambrian major geological events globally.</p>

Anchor Point Selection: Scale Alignment Based on an Inequality Criterion

For detecting differential item functioning (DIF) between two or more groups of test takers in the Rasch model, their item parameters need to be placed on the same scale. Typically this is done by means of choosing a set of so-called anchor items based on statistical tests or heuristics. Here the authors suggest an alternative strategy: By means of an inequality criterion from economics, the Gini Index, the item parameters are shifted to an optimal position where the item parameter estimates of the groups best overlap. Several toy examples, extensive simulation studies, and two empirical application examples are presented to illustrate the properties of the Gini Index as an anchor point selection criterion and compare its properties to those of the criterion used in the alignment approach of Asparouhov and Muthén. In particular, the authors show that—in addition to the globally optimal position for the anchor point—the criterion plot contains valuable additional information and may help discover unaccounted DIF-inducing multidimensionality. They further provide mathematical results that enable an efficient sparse grid optimization and make it feasible to extend the approach, for example, to multiple group scenarios.

Fall-Protection Harness Training: Donning Skill Improves with up to Four Repetitions

Injuries and fatalities from falling remain a major occupational safety concern. Among the multiple tactics for preventing fatal falls is the use of personal fall protection involving wearing a harness connected to a secure anchor point. This requires training to ensure trainees understand the importance of fall protection and have the skill to implement it correctly. One important skill is donning a fall protection harness and adjusting the straps. Those who conduct training on fall protection need to coach trainees through the steps involved in donning a harness. This study was undertaken to learn the benefits of practicing with the guidance of a coach. The experiment had university student volunteers watch a training video twice and then don a harness four times while being coached. Times for each of the five steps involved in donning and adjusting a harness were obtained for the 22 subjects who completed all steps. Time was used as the measure of skill level. The step of adjusting the leg straps accounted for the most time in all of the four repetitions. Total time to don fall protection was reduced with practice. The reduction followed a learning curve function based on a power model. According to this model, each doubling of the number of repetitions results in a 22.1% reduction in total time to don the harness.