Design and Application of Multiple Adaptability Evaluation Algorithms Based on UHVDC Digital Simulation Operating System

The digitally simulated UHVDC system provides an all-round, full-process, and full-scenario high-fidelity training and teaching platform for the switching operation of the UHVDC system, which can fully meet the training requirements of the operation and maintenance personnel of the converter station. In order to solve the problem of inaccurate evaluation due to the existence of multiple operation procedures for an operation target, an improved digital simulation system based on multiple adaptive evaluation algorithms was designed: the teacher uses a modular combination method to generate a standard operating procedure as the main line, and then uses the trainee’s simulated operating procedure as a supplement to jointly form a standard answer to adapt to the different operating procedures of the same operating task for the trainees. Based on this system, it can solve the problem of inaccurate evaluation caused by millions of answers in the simulation operation evaluation process. It provides fast, efficient and accurate evaluation results for the digital simulated UHVDC system switching operation procedure.

Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss

Objective: Species-specific pseudogenization of the CMAH gene during human evolution eliminated common mammalian sialic acid N -glycolylneuraminic acid (Neu5Gc) biosynthesis from its precursor N -acetylneuraminic acid (Neu5Ac). With metabolic nonhuman Neu5Gc incorporation into endothelia from red meat, the major dietary source, anti-Neu5Gc antibodies appeared. Human-like Ldlr −/ − Cmah −/− mice on a high-fat diet supplemented with a Neu5Gc-enriched mucin, to mimic human red meat consumption, suffered increased atherosclerosis if human-like anti-Neu5Gc antibodies were elicited. Approach and Results: We now ask whether interventional Neu5Ac feeding attenuates metabolically incorporated Neu5Gc-mediated inflammatory acceleration of atherogenesis in this Cmah −/− Ldlr −/− model system. Switching to a Neu5Gc-free high-fat diet or adding a 5-fold excess of Collocalia mucoid-derived Neu5Ac in high-fat diet protects against accelerated atherosclerosis. Switching completely from a Neu5Gc-rich to a Neu5Ac-rich diet further reduces severity. Remarkably, feeding Neu5Ac-enriched high-fat diet alone has a substantial intrinsic protective effect against atherosclerosis in Ldlr −/− mice even in the absence of dietary Neu5Gc but only in the human-like Cmah -null background. Conclusions: Interventional Neu5Ac feeding can mitigate or prevent the red meat/Neu5Gc-mediated increased risk for atherosclerosis, and has an intrinsic protective effect, even in the absence of Neu5Gc feeding. These findings suggest that similar interventions should be tried in humans and that Neu5Ac-enriched diets alone should also be investigated further.

Theoretical framework about optimal model of operation after intentional attacks considering transmission system switching

This research focuses on optimal post-intentional attack operation considering switching transmission systems. The applicable models for this process focus on the application of bi-level optimization methods that are capable of analyzing two possible scenarios in order to reduce the time of loss or departure from the demand of the electricity system. The main objective of this work is related to maintaining the minimum requirements that allow the operation of the Electric Power System, for this the approach of equations will be carried out that allows establishing the mathematical models in the event of intentional attacks, it must maintain the operation of the Electric System and react in the event of contingencies through the Optimal Switching of Transmission Lines.

Effective Real-Time Scheduling Optimization for Multi-Functional Mixed-Criticality Systems

The heterogeneous distributed embedded systems integrated of multiple functions with different criticality levels are multi-functional mixed-criticality systems (MMCSs). The state-of-the-art work has studied the real-time scheduling in MMCS; however, it is not well designed in system switching mechanism and operation which may lead to missing the deadlines of high-criticality functions and redundant operation. In this study, we improve and optimize the problem by developing an algorithm called rearrangement-based scheduling for MMCS (RSM). The RSM algorithm optimizes the following two main aspects. The first aspect is optimizing system-criticality switching mechanisms, including system criticality changed up and down. The second aspect is the effective operation in system-criticality switching to reduce redundant operation. Experiments are performed, and results show that the RSM algorithm can achieve lower overall makespan and deadline miss ratios (DMRs) than the existing algorithms.

From isoselectivity to syndioselectivity: Lewis base regulates stereochemistry in 2-vinylpyridine polymerization

We have developed an effective synthesis of syndiotactic poly(2-vinylpyridine) by a novel catalytic system. Switching from isoselective to syndioselective polymerization was achieved by adding Lewis base.

Mengapa Ipv6 Gagal ?

ABSTRACTIPv6 was introduced to replace IPv4 as the main IP address. However, despite being more than 15 years since itsstandardization, IPv6 failed to achieve any meaningful diffusion through the Internet. While previous researchhas debated, discussed and explored the IPv6 adoption, this study provides a theoretical perspective to investigatethe failure of IPv6 to diffuse from resistance perspective. Drawing on Tornatzky and Fleischer’s TOE (Technology-Organization-Environment) framework and integrating prior adoption and resistance literatures, we propose amodel of IPv6 resistance. The antecedents of the proposed model basically represent three dimensions of TOEframework including Technological context (lack of need, satisfaction with current system, switching cost andperceived of threat), Organizational context (resource barrier and IT sophistication) and Environmental context(regulatory support). Furthermore, the model can be used to explore and recognize why most of organization asend user still resist over the IPv6.Keywords: IPv6, resistance technology, adoption technologyABSTRAKIPv6 diperkenalkan untuk menggantikan IPv4 sebagai protocol pengalamatan utama di Internet. Tetapi meskipuntelah lebih dari 15 tahun ditetapkan sebagai standard, IPv6 gagal mencapai difusi yang berarti. Sementarapenelitian sebelumnya telah memperdebatkan, membahas dan mengeksplorasi adopsi IPv6, penelitian inimemberikan perspektif teoritis untuk menyelidiki kegagalan IPv6 untuk menyebar dari perspektif resistansi.Menggunakan kerangka kerja Tornatzky & Fleischer's TOE (Technology-Organization-Environment) danintegrasi dengan literatur adopsi dan resistensi sebelumnya, kami mengusulkan sebuah model resistensi IPv6.Antescedent dari model yang diusulkan pada dasarnya mewakili tiga dimensi kerangka TOE termasuk konteksTeknologi (lack of need, satisfaction with current system, switching cost and perceived of threat), konteksorganisasi ((resource barrier and IT sophistication) dan konteks lingkungan (regulatory support). Selanjutnya,model tersebut dapat digunakan untuk mengeksplorasi dan mengenali mengapa sebagian besar organisasi masihmenolak IPv6.Keywords: IPv6, penolakan teknologi, adopsi teknologi

Reversible π-system switching of thiophene-fused thiahexaphyrins by solvent and oxidation/reduction

The dithieno[3,4-b:3′,4′-d]thiophene unit is a new effective motif to realize the π-system switching of expanded porphyrins.