Dynamic and global environment, does not offer a spot for managers that improvise and make business moves without relevant information. In order to gain relevant information, it is necessary to observe processes through which value is generated. This implies adoption of process orientation and, based on it, business process management, as a way of running a business. Useful concept for operationalization of business process management is the Six Sigma. One of very important managerial decisions under the Six Sigma concept implementation concerns choosing the process for the improvement. Very often managers must take into the account subjective data, based on their opinion and experience, as personal impression. However, subjective data may become objective when adequate tools and methods for the analysis are used. Quantification is necessary for making decisions and, also, for tracking the results of their implementation. Beside statistical, significant information may provide methods from multi-criteria decision making.