This chapter defines the term “industrial gentrification” as the creation of new manufacturing zones that feature ecologically friendly, high-tech, and small-scale businesses designed to attract upwardly mobile, eco-friendly gentrifiers. I begin with an historic look at how zoning regulations created areas of sacrifice and gain. Initially, these regulations insulated wealthy residential zones from noxious facilities while interspersing industrial land uses and affordable housing. In the early 1960s, New York City elites reshuffled these spatial arrangements in ways that favored the growth of the finance, insurance, and real estate sectors and pushed industrial businesses to the city’s perimeters. Gentrification (and displacement) were a key part of this new economic strategy. After the 2008 recession, the Bloomberg administration rebooted the manufacturing economy as part of its larger sustainability agenda. However, like other green amenities, the location of low-tech manufacturing spaces corresponded with upscale redevelopment. This further concentrated heavy manufacturing facilities in non-gentrifying neighborhoods. Moreover, rather than reviving a lost employment sector, new manufacturing offered high-priced items produced by a small number of nonunionized, low-wage workers.