EVALUATION OF RANDOM BLOOD GLUCOSE LEVELS AMONG AMBULANT WOMEN

Background: Increasing blood sugar level may increase free radical compounds in type 2 diabetes. Free radical compounds can cause oxidative stress, thereby decreasing endogenous antioxidants such as reduced glutathione (GSH). Objective: This study aimed to determine whether random blood glucose levels affect GSH in type 2 diabetes patients within the Malay race. Methods: This study was observational with case-control, involving 25 patients with uncomplicated type 2 diabetes (receiving metformin and/or glimipiride) and 25 healthy controls. Random blood glucose levels were determined using ACCU-CHECK® Kit. Blood GSH levels were determined by Sigma GSH Assay Kit. Results: Results show that type 2 diabetes patients have a significantly lower random blood glucose level compared with those of age-matched normal subjects (p<0.0001). Type 2 diabetic patients had significantly lower levels of GSH (p=0.00) than those of age-matched normal subjects. We found a moderate negative correlation (r=-0.437 and p=0.02) between the level of random blood glucose and the level of GSH. Conclusion: The depletion of GSH during hyperglycemia may neutralize the free radicals indirectly generated by the abundant of glucose.

Download Full-text

Impact of sleep duration during pregnancy on the risk of gestational diabetes in the Japan environmental and Children’s study (JECS)

BMC Pregnancy and Childbirth ◽

10.1186/s12884-019-2632-9 ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 3

Author(s):

Mai Myoga ◽

◽

Mayumi Tsuji ◽

Rie Tanaka ◽

Eiji Shibata ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factor ◽

Blood Glucose ◽

Gestational Diabetes ◽

Sleep Duration ◽

Reference Group ◽

Oral Glucose ◽

Random Blood Glucose ◽

Glucose Levels ◽

Blood Glucose Levels

Abstract Background Gestational diabetes mellitus (GDM) has serious effects on both mother and child. Like Type 2 Diabetes Mellitus, it is increasing in prevalence world-wide. In addition to obesity, sleep duration has been named an important risk factor. Using a large cohort study, including data from 48,787 participants of the Japan Environment and Children’s Study (JECS), we examined the association between sleep duration and both random blood glucose levels and GDM rates during pregnancy. Methods Random blood glucose levels were measured during pregnancy. GDM diagnosis was based on the results of 75 g oral glucose tolerance test. Additional anthropometric data was collected from questionnaires for statistical analysis. Results Compared to mothers averaging 7 to < 10 h sleep (reference group), women receiving < 5 h or ≥ 10 h sleep exhibited significantly elevated random blood glucose levels. This was associated with an elevated risk for positive GDM screening (< 5 h sleep: OR 1.17 (0.96–1.44) p = 0.126; ≥10 h sleep: OR 1.13 (1.03–1.25) p = 0.006). Calculating the risk for GDM, women sleeping < 5 h or ≥ 10 h exhibited elevated risks of 1.31-fold and 1.21 respectively. However, this trend was not found to be significant. Conclusions Sleep is a critical factor in glucose metabolism, with both abnormally long and short sleep duration increasing random blood glucose levels in pregnant women. Moreover, the risk for positive GDM screening increases significantly with elevated sleep, ≥10 h per night. These findings are promising because they support the idea that sleep duration is a modifiable risk factor, and can be focused upon to improve health and pregnancy outcome.

Download Full-text

Low glycaemic index diet in patients prescribed clozapine: pilot study

Psychiatric Bulletin ◽

10.1192/pb.28.8.292 ◽

2004 ◽

Vol 28 (8) ◽

pp. 292-294 ◽

Cited By ~ 4

Author(s):

Helen Smith ◽

Tom White

Keyword(s):

Blood Glucose ◽

Pilot Study ◽

Glycaemic Index ◽

Clinical Implications ◽

Random Blood Glucose ◽

Glucose Levels ◽

Cholesterol Levels ◽

Blood Glucose Levels ◽

Potential Benefits ◽

The Mean

Aims and MethodThis study aimed to investigate the potential benefits of a low glycaemic index diet in patients with schizophrenia taking clozapine. Seven patients consented to participate in a 5-week pilot study. Measurements were taken of body weight, random blood glucose and cholesterol levels.ResultsThe mean weight loss per patient was 2.9 kg in 4 weeks. Random blood glucose levels reduced from a mean of 5.3 mmol/l at the beginning of the study to 4.7 mmol/l at the end.Clinical ImplicationsA low glycaemic index diet may possibly reduce the substantial cardiovascular risk in patients receiving antipsychotic medication.

Download Full-text

Association Between Atypical Antipsychotic with The Increase of Random Blood Glucose Levels In Schizophrenia Patients

Proceedings for Annual Meeting of The Japanese Pharmacological Society ◽

10.1254/jpssuppl.wcp2018.0_po4-11-4 ◽

2018 ◽

Vol WCP2018 (0) ◽

pp. PO4-11-4

Author(s):

Sufi Desrini ◽

Andra Gita Arumsari ◽

Rahma Yuantari

Keyword(s):

Blood Glucose ◽

Atypical Antipsychotic ◽

Random Blood Glucose ◽

Glucose Levels ◽

Blood Glucose Levels

Download Full-text

A cross sectional screen for diabetes correlating physical activity and blood glucose levels

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20194023 ◽

2019 ◽

Vol 6 (9) ◽

pp. 4094

Author(s):

Kulshreshth Sinha ◽

Andrea Pereira Kolla ◽

Rakhi Bajpai ◽

Varaprasad Kolla

Keyword(s):

Physical Activity ◽

Blood Glucose ◽

Physical Inactivity ◽

Diabetes Management ◽

Rural Populations ◽

Undiagnosed Diabetes ◽

Activity Increase ◽

Random Blood Glucose ◽

Glucose Levels ◽

Blood Glucose Levels

Background: Diabetes, a chronic disease, is presently a rapidly growing epidemic globally. The risk of diabetes type 2 is greatly increasing with change in lifestyle factors, urbanization, high blood pressure, overweight or obesity, physical inactivity and poor diet. It’s one of the reasons for premature death and disability and the number of cases are drastically increasing every year.Methods: 81 subjects above 18 years of age were considered for the screening. Random blood glucose levels were tested using the Thyrocare Sugar scan glucometer strips. Physical activity data was collected using a questionnaire. Based on the extent of physical activity, the subjects we grouped into three different categories. Data was analyzed and expressed using basic statistical tools in MS Excel 2007.Results: 6.17% of the rural population of Kendri, with mean age 47.4 years, had undiagnosed diabetes. The mean blood glucose level in diabetes positive cases was 279.8 mg/dL. A correlation of random blood glucose levels of the subjects with the extent of their physical activity was observed, where a decrease in physical activity/increase in physical inactivity showed an increase in blood glucose levels.Conclusions: From our study we conclude that undiagnosed diabetes is prevalent amongst the rural populations of Kendri, Chhattisgarh and low physical activity correlated with an increase of blood glucose levels, suggesting an urgent need to create health awareness, with emphasis on increase in physical activity, literacy and diabetes management, obesity, specifically among the illiterate and underprivileged rural populations.

Download Full-text