Association Between Reproductive Life Span and Incident Nonfatal Cardiovascular Disease

Murphy's hypothesis that variation in reproductive life span is an adaptive response to variation in the predictability of reproductive success is examined. Murphy's contention that this hypothesis explains the variation in reproductive life span within the clupeids is reexamined incorporating further data on the Peruvian anchovy (Engraulis ringens). A nonsignificant correlation is now obtained between reproductive life span and brood strength variation; thus, the hypothesis is called into question. An alternative explanation is presented that considers the interaction between life history parameters: because it is necessary for the intrinsic rate of increase to exceed zero, variation in one parameter must be associated with variation in at least one other parameter. In the clupeids it is noted that the age of maturity and reproductive life span vary in concert and it is suggested that this provides an explanation of variation in reproductive life span. These two hypotheses are examined using data on the family Pleuronectidae, the flatfish. No correlation exists between reproductive life span and the degree of fluctuation in brood strength but there is a significant correlation between reproductive life span and age of maturity. It is concluded that variation in reproductive life span within the flatfish group is not a response to variation in reproductive success but rather a correlate of variation in age of maturity.Key words: flatfish, Pleuronectidae, iteroparity, natural selection, reproduction, clupeids

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Concept of Granthi with reference to uterine fibroid: An Ayurveda review

National Journal of Research in Ayurved Science ◽

10.52482/ayurlog.v9i02.840 ◽

2021 ◽

Vol 9 (02) ◽

Author(s):

Jaya Umate ◽

Soudamini Chaudhari

Keyword(s):

Life Span ◽

Uterine Fibroid ◽

Uterine Fibroids ◽

Modern Science ◽

Reproductive Age ◽

Significant Morbidity ◽

Reproductive Life ◽

Reproductive Life Span ◽

Gynecological Disease ◽

Reproductive Age Group

Uterine fibroids are the commonest benign tumor of the uterus and also the commonest benign solid tumor in the female. It can cause significant morbidity in women of a reproductive life span. The exact cause of uterine fibroid is unknown. Prevalence of uterine fibroid 5 -20 % of women in the reproductive age group. It can cause significant morbidity in women of a reproductive life span. Not all fibroids cause symptoms. 50% of women are asymptomatic. Fibroids mainly cause symptoms like menorrhagia, dysmenorrhea and cause pressure symptoms on adjacent viscera i. e. bladder, uterus, rectum which affects the everyday activities of women. In Ayurveda all gynecological disease explained under the term yonivyapad. It can be explained as the anatomical and functional abnormalities of the female reproductive system. In Ayurveda granthi can be correlated with the uterine fibroid. In modern science uterine fibroid treats medically, surgically. But it is challenging to establish a satisfactory conservatory medical treatment to date. so in Ayurveda the main purpose is the management of granthi by samprapti vighatan by use of medicine.

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PohnB6F1: A Cross of Wild and Domestic Mice That Is a New Model of Extended Female Reproductive Life Span

The Journals of Gerontology Series A ◽

10.1093/gerona/62.11.1187 ◽

2007 ◽

Vol 62 (11) ◽

pp. 1187-1198 ◽

Cited By ~ 16

Author(s):

K. Flurkey ◽

Y. Brandvain ◽

S. Klebanov ◽

S. N. Austad ◽

R. A. Miller ◽

...

Keyword(s):

Life Span ◽

New Model ◽

Reproductive Life ◽

Reproductive Life Span

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Chromosome errors in human eggs shape natural fertility over reproductive life span

Science ◽

10.1126/science.aav7321 ◽

2019 ◽

Vol 365 (6460) ◽

pp. 1466-1469 ◽

Cited By ~ 30

Author(s):

Jennifer R. Gruhn ◽

Agata P. Zielinska ◽

Vallari Shukla ◽

Robert Blanshard ◽

Antonio Capalbo ◽

...

Keyword(s):

Life Span ◽

Chromosome Segregation ◽

Pregnancy Loss ◽

Natural Fertility ◽

Congenital Disorders ◽

Human Oocytes ◽

Reproductive Life ◽

Reproductive Life Span ◽

Quantitative Explanation ◽

Chromosome Nondisjunction

Chromosome errors, or aneuploidy, affect an exceptionally high number of human conceptions, causing pregnancy loss and congenital disorders. Here, we have followed chromosome segregation in human oocytes from females aged 9 to 43 years and report that aneuploidy follows a U-curve. Specific segregation error types show different age dependencies, providing a quantitative explanation for the U-curve. Whole-chromosome nondisjunction events are preferentially associated with increased aneuploidy in young girls, whereas centromeric and more extensive cohesion loss limit fertility as women age. Our findings suggest that chromosomal errors originating in oocytes determine the curve of natural fertility in humans.

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