A Hydrogel Microneedle Patch for Point‐of‐Care Testing Based on Skin Interstitial Fluid

2020 ◽  
Vol 9 (4) ◽  
pp. 1901201 ◽  
Author(s):  
Rongyan He ◽  
Yan Niu ◽  
Zedong Li ◽  
Ang Li ◽  
Huayuan Yang ◽  
...  
Author(s):  
Sheng Zhang ◽  
Junyan Zeng ◽  
Chunge Wang ◽  
Luying Feng ◽  
Zening Song ◽  
...  

Diabetes and its complications have become a worldwide concern that influences human health negatively and even leads to death. The real-time and convenient glucose detection in biofluids is urgently needed. Traditional glucose testing is detecting glucose in blood and is invasive, which cannot be continuous and results in discomfort for the users. Consequently, wearable glucose sensors toward continuous point-of-care glucose testing in biofluids have attracted great attention, and the trend of glucose testing is from invasive to non-invasive. In this review, the wearable point-of-care glucose sensors for the detection of different biofluids including blood, sweat, saliva, tears, and interstitial fluid are discussed, and the future trend of development is prospected.


2020 ◽  
Vol 27 ◽  
Author(s):  
Yi Zhang

: Point-of-care (POC) testing decentralizes the diagnostic tests to the sites near the patient. Many POC tests rely microfluidic platforms for sample-to-answer analysis. Compared to other microfluidic systems, magnetic digital microfluidics demonstrate compelling advantages for POC diagnostics. In this review, we have examined the capability of magnetic digital microfluidics-based POC diagnostic platforms. More importantly, we have categorized POC settings into three classes based on “where is the point”, “who to care” and “how to test”, and evaluated the suitability of magnetic digital microfluidics in various POC settings. Furthermore, we have addressed other technical issues associated with POC testing such as controlled environment, sample-system interface, system integration and information connectivity. We hope this review would provide a guideline for the future development of magnetic digital microfluidics-based platforms for POC testing.


The Analyst ◽  
2021 ◽  
Author(s):  
Tianshu Chu ◽  
Huili Wang ◽  
Yumeng Qiu ◽  
Haoxi Luo ◽  
Bingfang He ◽  
...  

Wearable sensors play a key role in point-of-care testing (POCT) for its flexible and integration capability on sensitive physiological and biochemical sensing. Here, we present a multifunction wearable silk patch...


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