Biomimetic Ultraflexible Piezoresistive Flow Sensor Based on Graphene Nanosheets and PVA Hydrogel

2021 ◽  
pp. 2100783
Author(s):  
Sajad Abolpour Moshizi ◽  
Hamed Moradi ◽  
Shuying Wu ◽  
Zhao Jun Han ◽  
Amir Razmjou ◽  
...  
2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Sajad Abolpour Moshizi ◽  
Shohreh Azadi ◽  
Andrew Belford ◽  
Amir Razmjou ◽  
Shuying Wu ◽  
...  

AbstractThis paper suggests development of a flexible, lightweight, and ultra-sensitive piezoresistive flow sensor based on vertical graphene nanosheets (VGNs) with a mazelike structure. The sensor was thoroughly characterized for steady-state and oscillatory water flow monitoring applications. The results demonstrated a high sensitivity (103.91 mV (mm/s)−1) and a very low-velocity detection threshold (1.127 mm s−1) in steady-state flow monitoring. As one of many potential applications, we demonstrated that the proposed VGNs/PDMS flow sensor can closely mimic the vestibular hair cell sensors housed inside the semicircular canals (SCCs). As a proof of concept, magnetic resonance imaging of the human inner ear was conducted to measure the dimensions of the SCCs and to develop a 3D printed lateral semicircular canal (LSCC). The sensor was embedded into the artificial LSCC and tested for various physiological movements. The obtained results indicate that the flow sensor is able to distinguish minute changes in the rotational axis physical geometry, frequency, and amplitude. The success of this study paves the way for extending this technology not only to vestibular organ prosthesis but also to other applications such as blood/urine flow monitoring, intravenous therapy (IV), water leakage monitoring, and unmanned underwater robots through incorporation of the appropriate packaging of devices.


2020 ◽  
Vol 21 (11) ◽  
pp. 1016-1027 ◽  
Author(s):  
Fatemeh Emadi ◽  
Arash Emadi ◽  
Ahmad Gholami

Graphene Derivatives (GDs) have captured the interest and imagination of pharmaceutical scientists. This review exclusively provides pharmacokinetics and pharmacodynamics information with a particular focus on biopharmaceuticals. GDs can be used as multipurpose pharmaceutical delivery systems due to their ultra-high surface area, flexibility, and fast mobility of charge carriers. Improved effects, targeted delivery to tissues, controlled release profiles, visualization of biodistribution and clearance, and overcoming drug resistance are examples of the benefits of GDs. This review focuses on the application of GDs for the delivery of biopharmaceuticals. Also, the pharmacokinetic properties and the advantage of using GDs in pharmaceutics will be reviewed to achieve a comprehensive understanding about the GDs in pharmaceutical sciences.


2015 ◽  
Vol 4 (9) ◽  
pp. 974-978 ◽  
Author(s):  
Shan Wang ◽  
Haolong Li ◽  
Dan Li ◽  
Tianyang Xu ◽  
Shilin Zhang ◽  
...  

Nano Letters ◽  
2021 ◽  
Author(s):  
Kecheng Guan ◽  
Yuandong Jia ◽  
Yuqing Lin ◽  
Shengyao Wang ◽  
Hideto Matsuyama

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