scholarly journals Biomarkers for Alzheimer’s disease in Black populations: A scoping review

2021 ◽  
Vol 17 (S10) ◽  
Author(s):  
Stacey Moeller ◽  
Samantha E John
Author(s):  
Hanna Maria Elonheimo ◽  
Helle Raun Andersen ◽  
Andromachi Katsonouri ◽  
Hanna Tolonen

Alzheimer’s disease (AD) is the most common form of dementia, prevalent in approximately 50–70% of the dementia cases. AD affects memory, and it is a progressive disease interfering with cognitive abilities, behaviour and functioning of the person affected. In 2015, there were 47 million people affected by dementia worldwide, and the figure was estimated to increase to 75 million in 2030 and to 132 million by 2050. In the framework of European Human Biomonitoring Initiative (HBM4EU), 18 substances or substance groups were prioritized for investigation. For each of the priority substances, a scoping document was prepared. Based on these scoping documents and complementary review of the recent literature, a scoping review of HBM4EU-priority substances which might be associated with AD was conducted. A possible association between risk of AD and pesticides was detected. For mercury (Hg), association is possible but inconsistent. Regarding cadmium (Cd) and arsenic (As), the results are inconsistent but inclined towards possible associations between the substances and the risk of disease. The evidence regarding lead (Pb) was weaker than for the other substances; however, possible associations exist. Although there is evidence of adverse neurological effects of environmental substances, more research is needed. Environmental chemical exposure and the related hazards are essential concerns for public health, and they could be preventable.


2019 ◽  
Vol 96 ◽  
pp. 119-131 ◽  
Author(s):  
Kyungmi Lee ◽  
Frank Puga ◽  
Carolyn E.Z. Pickering ◽  
Sara S. Masoud ◽  
Carole L. White

2017 ◽  
Vol 1 (suppl_1) ◽  
pp. 398-398
Author(s):  
G. Mathur ◽  
K. Mehndiratta ◽  
T. Yasmina ◽  
N. Bhela ◽  
R.M. Mirza

2020 ◽  
Author(s):  
Johanna Thunell ◽  
Yi Chen ◽  
Geoffrey Joyce ◽  
Douglas Barthold ◽  
Paul G. Shekelle ◽  
...  

2016 ◽  
Vol 12 ◽  
pp. P596-P596 ◽  
Author(s):  
Katherine S. McGilton ◽  
Fiona Hobler ◽  
Dawn Guthrie ◽  
Jennifer Campos ◽  
Jonathan Jarry ◽  
...  

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Eunhee Kim ◽  
Andrius Baskys ◽  
Anandi V. Law ◽  
Moom R. Roosan ◽  
Yan Li ◽  
...  

AbstractAlzheimer’s Disease (AD) is one of the most prevalent neurodegenerative chronic diseases. As it progresses, patients become increasingly dependent, and their caregivers are burdened with the increasing demand for managing their care. Mobile health (mHealth) technology, such as smartphone applications, can support the need of these caregivers. This paper examines the published academic literature of mHealth applications that support the caregivers of AD patients. Following the PRISMA for scoping reviews, we searched published literature in five electronic databases between January 2014 and January 2021. Twelve articles were included in the final review. Six themes emerged based on the functionalities provided by the reviewed applications for caregivers. They are tracking, task management, monitoring, caregiver mental support, education, and caregiver communication platform. The review revealed that mHealth applications for AD patients’ caregivers are inadequate. There is an opportunity for industry, government, and academia to fill the unmet need of these caregiver.


2018 ◽  
Vol 15 (10) ◽  
pp. 975-983 ◽  
Author(s):  
Petra Maresova ◽  
Signe Tomsone ◽  
Petre Lameski ◽  
Joana Madureira ◽  
Ana Mendes ◽  
...  

In the nineties, numerous studies began to highlight the problem of the increasing number of people with Alzheimer’s disease in developed countries, especially in the context of demographic progress. At the same time, the 21st century is typical of the development of advanced technologies that penetrate all areas of human life. Digital devices, sensors, and intelligent applications are tools that can help seniors and allow better communication and control of their caregivers. The aim of the paper is to provide an up-to-date summary of the use of technological solutions for improving health and safety for people with Alzheimer’s disease. Firstly, the problems and needs of senior citizens with Alzheimer’s disease (AD) and their caregivers are specified. Secondly, a scoping review is performed regarding the technological solutions suggested to assist this specific group of patients. Works obtained from the following libraries are used in this scoping review: Web of Science, PubMed, Springer, ACM and IEEE Xplore. Four independent reviewers screened the identified records and selected relevant articles which were published in the period from 2007 to 2018. A total of 6,705 publications were selected. In all, 128 full papers were screened. Results obtained from the relevant studies were furthermore divided into the following categories according to the type and use of technologies: devices, processing, and activity recognition. The leading technological solution in the category of devices are wearables and ambient noninvasive sensors. The introduction and utilization of these technologies, however, bring about challenges in acceptability, durability, ease of use, communication, and power requirements. Furthermore, it needs to be pointed out that these technological solutions should be based on open standards.


Dementia ◽  
2021 ◽  
pp. 147130122110217
Author(s):  
Maral R Torossian

Background Supporting human dignity is the essence of delivery of care. Dignity is one’s sense of self-value that is influenced by the perceived value attributed to the individual from others. Individuals with Alzheimer’s disease and related dementias (ADRD) are at risk of violations of their dignity, due to their diminished autonomy, the alteration in their sense of self, the loss of meaningful social roles, and their limited interactions with peers and confirmation of identity. Objectives A scoping review was conducted to explore the state of art regarding the dignity of individuals with ADRD. Methods: A search was conducted using CINAHL, PubMed, Web of Science, and PsycINFO. Relevant articles were analyzed and organized based on the themes they addressed, and a narrative description of findings was presented. Results Twenty-six articles were included in the review. Findings highlighted characteristics of care that affected the dignity of these individuals. Researchers found that care was task-centered, depersonalized, and lacked a genuine connection. Individuals with ADRD experienced embarrassment, lack of freedom, and powerlessness, which contributed to feelings of being devalued, and threatened their dignity. Studies testing interventions to enhance dignity were either inconclusive, lacked rigor, or had no lasting effect. Conclusion: The dignity of individuals with ADRD may be violated during healthcare interactions. More research is needed to objectively measure the dignity of these individuals and examine the effectiveness of interventions aimed at promoting dignity.


Sign in / Sign up

Export Citation Format

Share Document