Quantitative effects of theelin on body growth and endocrine glands in young albino rats

1937 ◽  
Vol 69 (2) ◽  
pp. 171-177 ◽  
Author(s):  
Clay B. Freudenberger ◽  
Fred W. Clausen
Keyword(s):  
Body Growth ◽  
Albino Rats ◽  
Endocrine Glands

Contrasting effects of stress and cortisol overdosage in the rat

1959 ◽  
Vol 196 (5) ◽  
pp. 946-948 ◽  
Author(s):  
C. E. Hall ◽  
O. Hall
Keyword(s):  
Blood Pressure ◽  
Chronic Stress ◽  
Body Growth ◽  
Pressure Effects ◽  
Albino Rats ◽  
Thymus Involution ◽  
Electrical Shocks ◽  
Blood Pressure Effects ◽  
Stress States ◽  
Preputial Glands

Immature female albino rats were subjected to chronic stress and to cortisol overdosage singly and in combination. At a dosage of 1 mg/day the steroid produced slight augmentation of blood pressure, moderate inhibition of growth and great involution of the thymus. Stress, in the form of intermittently applied electrical shocks, although it had little effect on the thymus or on body growth, produced slight adrenal hypertrophy and a considerable hypertrophy of the preputial glands. Stress and cortisol together acted synergistically on body growth and thymus involution; but cortisol dominated the adrenal response and stress that of the preputial glands. There was only suggestive evidence that blood pressure effects of cortisol were augmented by stress. The possible usefulness of preputial hypertrophy in the assessment of chronic stress states is discussed.

scholarly journals EFFECT OF FEEDING THE PINEAL BODY UPON THE DEVELOPMENT OF THE ALBINO RAT

1920 ◽  
Vol 31 (3) ◽  
pp. 335-344 ◽  
Author(s):  
Warren R. Sisson ◽  
John M. T. Finney
Keyword(s):  
Microscopic Examination ◽  
Reproductive Organs ◽  
Developmental Changes ◽  
Pineal Body ◽  
Albino Rats ◽  
Endocrine Glands ◽  
Albino Rat ◽  
Microscopic Studies ◽  
And Control ◽  
Effect Of Feeding

The pineal body of young calves was fed to albino rats beginning at the age of 3 weeks and extending over periods of from 3 to 6 weeks. Four litters of rats were used. Of these, fourteen rats were fed the pineal powder and ten were used as control subjects. Observations in regard to developmental changes and microscopic examination of the endocrine glands and reproductive organs were made. The pineal-fed rats of the first two litters remained somewhat smaller than their controls. The pineal-fed and control animals of Litters 3 and 4 showed no differences in development. Microscopic studies showed no differences between pineal-fed and control rats. We may therefore conclude that feeding the desiccated pineal body of young calves to young albino rats fails to produce any effect upon the early development of these animals.

scholarly journals A COMPARISON OF BONE GROWTH IN LENGTH WITH BONE GROWTH IN WEIGHT

1925 ◽  
Vol 9 (1) ◽  
pp. 63-71 ◽  
Author(s):  
Frederick S. Hammett
Keyword(s):  
Cell Size ◽  
Bone Strength ◽  
Bone Growth ◽  
Growth Period ◽  
Cell Number ◽  
Body Growth ◽  
Albino Rats ◽  
Male And Female ◽  
Growth Capacity ◽  
Chemical Differentiation

1. The growth capacity in length of the humerus and femur of male and female albino rats during the growth period from 23 to 150 days of age is less than the growth capacity in weight. This shows that the processes productive of bone strength are more active than those concerned in longitudinal expansion or stature. 2. Growth capacity in length is less affected than is growth capacity in weight by the systemic determinants and the factors incident to sex, weaning, and puberty. Since the findings as a whole are consistent with the assumption that bone growth in length is largely a matter of increase in cell number, while bone growth in weight is largely a matter of increase in cell size and density, the generalization is made that, in the bones at least, growth by increase in cell number is more stable than growth by increase in cell size and density. 3. A stabilization and approximation to a uniform level of growth capacity in both length and weight occurs at the culmination of puberty, which is quite like that taking place in the chemical differentiation at the same time. 4. Bone growth in length is more like body growth in length than bone growth in weight is like body growth in weight.

Effects of renovascular hypertension on rat adrenal zona glomerulosa

1978 ◽  
Vol 36 (2) ◽  
pp. 582-583
Author(s):  
G. Mazzocchi ◽  
P. Rebuffat ◽  
C. Robba ◽  
P. Vassanelli ◽  
G. G. Nussdorfer
Keyword(s):  
Renovascular Hypertension ◽  
Left Kidney ◽  
Renin Angiotensin System ◽  
Plasma Renin ◽  
Zona Glomerulosa ◽  
Ultrastructural Changes ◽  
Albino Rats ◽  
Left Renal Artery ◽  
Angiotensin System ◽  
And Control

It is well known that the rat adrenal zona glomerulosa steroidogenic activity is controlled by the renin-angiotensin system. The ultrastructural changes in the rat zona glomerulosa cells induced by renovascular hypertension were described previously, but as far as we are aware no correlated biochemical and morphometric investigations were performed.Twenty adult male albino rats were divided into 2 experimental groups. One group was subjected to restriction of blood flow to the left kidney by the application of a silver clip about the left renal artery. The other group was sham-operated and served as a control. Renovascular hypertension developed in about 10 days: sistolic blood pressure averaged 165 ± 6. 4 mmHg, whereas it was about 110 ± 3. 8 mmHg in the control animals. The hypertensive and control rats were sacrificed 20 days after the operation. The blood was collected and plasma renin activity was determined by radioimmunological methods. The aldosterone concentration was radioimmunologically assayed both in the plasma and in the homogenate of the left capsular adrenal gland.

Further Studies on the Ultrastructure of Harderian Gland in Adult Rats

1974 ◽  
Vol 32 ◽  
pp. 288-289
Author(s):  
Alfredo Feria-Velasco ◽  
Guadalupe Tapia-Arizmendi
Keyword(s):  
Fine Structure ◽  
Domestic Fowl ◽  
Animal Species ◽  
Acinar Cells ◽  
Harderian Gland ◽  
Myoepithelial Cells ◽  
The Other ◽  
Albino Rats ◽  
Adult Rats ◽  
Cell Components

The fine structure of the Harderian gland has been described in some animal species (hamster, rabbit, mouse, domestic fowl and albino rats). There are only two reports in the literature dealing on the ultrastructure of rat Harderian gland in adult animals. In one of them the author describes the myoepithelial cells in methacrylate-embbeded tissue, and the other deals with the maturation of the acinar cells and the formation of the secretory droplets. The aim of the present work is to analize the relationships among the acinar cell components and to describe the two types of cells located at the perifery of the acini.

Cell Fine Structure as Revealed in Dessicator-Dried Resinless Sections

1981 ◽  
Vol 39 ◽  
pp. 622-623
Author(s):  
R. P. Becker ◽  
J. J. Wolosewick ◽  
J. Ross-Stanton
Keyword(s):  
Fine Structure ◽  
Tannic Acid ◽  
Three Dimensional ◽  
Albino Rats ◽  
Cell Organelles ◽  
Vascular Perfusion ◽  
Thin Sections ◽  
Carbon Coated ◽  
Embedding Medium ◽  
Polyethylene Glycol 6000

Methodology has been introduced recently which allows transmission and scanning electron microscopy of cell fine structure in semi-thin sections unencumbered by an embedding medium. Images obtained from these “resinless” sections show a three-dimensional lattice of microtrabeculfee contiguous with cytoskeletal structures and membrane-bounded cell organelles. Visualization of these structures, especially of the matiiDra-nous components, can be facilitated by employing tannic acid in the fixation step and dessicator drying, as reported here.Albino rats were fixed by vascular perfusion with 2% glutaraldehyde or 1.5% depolymerized paraformaldehyde plus 2.5% glutaraldehyde in 0.1M sodium cacodylate (pH 7.4). Tissues were removed and minced in the fixative and stored overnight in fixative containing 4% tannic acid. The tissues were rinsed in buffer (0.2M cacodylate), exposed to 1% buffered osmium tetroxide, dehydrated in ethyl alcohol, and embedded in pure polyethylene glycol-6000 (PEG). Sections were cut on glass knives with a Sorvall MT-1 microtome and mounted onto poly-L-lysine, formvar-carbon coated grids while submerged in a solution of 95% ethanol containing 5% PEG.

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