Using a Personal Glucose Meter and Alkaline Phosphatase for Point-of-Care Quantification of Galactose-1-Phosphate Uridyltransferase in Clinical Galactosemia Diagnosis

2015 ◽  
Vol 10 (10) ◽  
pp. 2221-2227 ◽  
Author(s):  
Jingjing Zhang ◽  
Yu Xiang ◽  
Donna E. Novak ◽  
George E. Hoganson ◽  
Junjie Zhu ◽  
...  
Proceedings ◽  
2020 ◽  
Vol 60 (1) ◽  
pp. 24
Author(s):  
Clara Abardía-Serrano ◽  
Rebeca Miranda-Castro ◽  
Noemí de-los-Santos-Álvarez ◽  
María Jesús Lobo-Castañón

A sandwich genoassay for the detection of PCA3, a nucleic acid biomarker overexpressed in the urine of prostate cancer patients, has been developed by using the enzyme alkaline phosphatase (ALP) as a tracer of the hybrid generated onto the surface of magnetic particles. ALP converts D-glucose-1-phosphate into D-glucose, which is quantified with a personal glucose meter. The resulting methodology allows the reliable detection of PCA3 at low picomolar levels, thus fostering massive screening of prostate cancer.


The Analyst ◽  
2019 ◽  
Vol 144 (20) ◽  
pp. 6019-6024 ◽  
Author(s):  
Feifei Sun ◽  
Xiaomei Sun ◽  
Yijing Jia ◽  
Zhian Hu ◽  
Shenghao Xu ◽  
...  

We report a point-of-care immunosensor coupled with a rolling circle reaction and a personal glucose meter for sensitive detection of PSA.


2015 ◽  
Vol 64 ◽  
pp. 161-164 ◽  
Author(s):  
Qing Wang ◽  
Fang Liu ◽  
Xiaohai Yang ◽  
Kemin Wang ◽  
Hui Wang ◽  
...  

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