scholarly journals Stem cell microencapsulation for phenotypic control, bioprocessing, and transplantation

2013 ◽  
Vol 110 (3) ◽  
pp. 667-682 ◽  
Author(s):  
Jenna L. Wilson ◽  
Todd C. McDevitt
Keyword(s):  
Stem Cell ◽  
Cell Microencapsulation

scholarly journals Development of double-layered alginate-chitosan hydrogels for human stem cell microencapsulation

2019 ◽  
Author(s):  
Retno Wahyu Nurhayati ◽  
Rafianto Dwi Cahyo ◽  
Kamila Alawiyah ◽  
Gita Pratama ◽  
Elizabeth Agustina ◽  
...  
Keyword(s):  
Stem Cell ◽  
Human Stem Cell ◽  
Cell Microencapsulation ◽  
Chitosan Hydrogels

scholarly journals Hydrogel Biomaterials for Stem Cell Microencapsulation

Polymers ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 997 ◽  
Author(s):  
Goeun Choe ◽  
Junha Park ◽  
Hansoo Park ◽  
Jae Lee
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Cell Encapsulation ◽  
Cell Based Therapy ◽  
Promising Strategy ◽  
Therapeutic Molecules ◽  
Cell Microencapsulation ◽  
Delivery Vehicles ◽  
Therapeutic Activities

Stem cell transplantation has been recognized as a promising strategy to induce the regeneration of injured and diseased tissues and sustain therapeutic molecules for prolonged periods in vivo. However, stem cell-based therapy is often ineffective due to low survival, poor engraftment, and a lack of site-specificity. Hydrogels can offer several advantages as cell delivery vehicles, including cell stabilization and the provision of tissue-like environments with specific cellular signals; however, the administration of bulk hydrogels is still not appropriate to obtain safe and effective outcomes. Hence, stem cell encapsulation in uniform micro-sized hydrogels and their transplantation in vivo have recently garnered great attention for minimally invasive administration and the enhancement of therapeutic activities of the transplanted stem cells. Several important methods for stem cell microencapsulation are described in this review. In addition, various natural and synthetic polymers, which have been employed for the microencapsulation of stem cells, are reviewed in this article.

Author response for "Inhibition of neural stem cell aging through the transient induction of reprogramming factors"

2020 ◽  
Author(s):  
Min Ji Han ◽  
Won Ji Lee ◽  
Joonhyuk Choi ◽  
Yean Ju Hong ◽  
Sang Jun Uhm ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Author Response ◽  
Cell Aging ◽  
Stem Cell Aging ◽  
Reprogramming Factors

The Response of Testes Cells to Low Level, Single dose Helium Particle Irradiation

1982 ◽  
Vol 40 ◽  
pp. 252-253
Author(s):  
D.E. Philpott ◽  
W. Sapp ◽  
C. Williams ◽  
J. Stevenson ◽  
S. Black ◽  
...  
Keyword(s):  
Stem Cell ◽  
Single Dose ◽  
B Cell ◽  
Cell Survival ◽  
Spermatogonial Stem Cell ◽  
Low Doses ◽  
Particle Irradiation ◽  
Stem Cell Survival ◽  
Irradiation Injury ◽  
Radio Sensitivity

Spermatogonial stem-cell survival after irradiation injury has been studied in rodents by histological counts of surviving cells. Many studies, including previous work from our laboratory, show that the spermatogonial population demonstrates a heterogeneous response to irradiation. The spermatogonia increase in radio-sensitivity as differentiation proceeds through the sequence As - Apr - A1 - A2 - A3 - A4 - In - B. The stem (As) cell is the most resistant and the B cell is the most sensitive. The purpose of this work is to investigate the response of spermatogonial cell to low doses (less than 10 0 rads) of helium particle irradiation.

The Response of Testis Cells to Low Dose X-Irradiation

1981 ◽  
Vol 39 ◽  
pp. 542-543
Author(s):  
D. E. Philpott ◽  
W. Sapp ◽  
C. Williams ◽  
Joann Stevenson ◽  
S. Black
Keyword(s):  
Electron Microscopy ◽  
Stem Cell ◽  
Light Microscopy ◽  
Dose Level ◽  
Cross Sections ◽  
Low Dose ◽  
Light And Electron Microscopy ◽  
Cellular Responses ◽  
Post Irradiation ◽  
X Irradiation

The response of spermatogonial cells to X-irradiation is well documented. It has been shown that there is a radiation resistent stem cell (As) which, after irradiation, replenishes the seminiferous epithelium. Most investigations in this area have dealt with radiation dosages of 100R or more. This study was undertaken to observe cellular responses at doses less than 100R of X-irradiation utilizing a system in which the tissue can be used for light and electron microscopy.Brown B6D2F1 mice aged 16 weeks were exposed to X-irradiation (225KeV; 15mA; filter 0.35 Cu; 50-60 R/min). Four mice were irradiated at each dose level between 1 and 100 rads. Testes were removed 3 days post-irradiation, fixed, and embedded. Sections were cut at 2 microns for light microscopy. After staining, surviving spermatogonia were identified and counted in tubule cross sections. The surviving fraction of spermatogonia compared to control, S/S0, was plotted against dose to give the curve shown in Fig. 1.

The early development of antenna and antennal sensilla in the noctuid moth, Agrotis segetum (Insecta: Lepidoptera)

1990 ◽  
Vol 48 (3) ◽  
pp. 502-503
Author(s):  
Eric Hallberg ◽  
Lina Hansén
Keyword(s):  
Cell Death ◽  
Stem Cell ◽  
Early Development ◽  
Larval Stage ◽  
Pupal Stage ◽  
Agrotis Segetum ◽  
Antennal Sensilla ◽  
Noctuid Moth ◽  
Standard Procedures

The antennal rudiments in lepidopterous insects are present as disks during the larval stage. The tubular double-walled antennal disk is present beneath the larval antenna, and its inner layer gives rise to the adult antenna during the pupal stage. The sensilla develop from a cluster of cells that are derived from one stem cell, which gives rise to both sensory and enveloping cells. During the morphogenesis of the sensillum these cells undergo major transformations, including cell death. In the moth Agrotis segetum the pupal stage lasts about 14 days (temperature, 25°C). The antennae, clearly seen from the exterior, were dissected and fixed according to standard procedures (3 % glutaraldehyde in 0.15 M cacaodylate buffer, followed by 1 % osmiumtetroxide in the same buffer). Pupae from day 1 to day 8, of both sexes were studied.

Generation of functionally mature dendritic cells from the multipotential stem cell line FDCP-mix

2000 ◽  
Vol 111 (3) ◽  
pp. 890-897 ◽  
Author(s):  
Timm Schroeder ◽  
Claudia Lange ◽  
John Strehl ◽  
Ursula Just
Keyword(s):  
Dendritic Cells ◽  
Stem Cell ◽  
Cell Line ◽  
Stem Cell Line

President Bush Vetoes Expansion of Federal Stem Cell Funding

2006 ◽  
Vol 37 (9) ◽  
pp. 3
Author(s):  
TODD ZWILLICH
Keyword(s):  
Stem Cell ◽  
President Bush
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