scholarly journals The effect of systemic antidepressant treatments in early stage on neurocognitive function of euthymic bipolar patients initiated with a depressive onset: An observational, cross‐sectional, single‐blind study protocol

2021 ◽  
Author(s):  
Huizeng Yang ◽  
Yuanyuan Liu ◽  
Chenghao Yang ◽  
Xiaoling Lin
Keyword(s):  
Study Protocol ◽  
Early Stage ◽  
Neurocognitive Function ◽  
Blind Study ◽  
Cross Sectional ◽  
Antidepressant Treatments ◽  
Bipolar Patients ◽  
Single Blind

scholarly journals Goal-oriented cognitive rehabilitation in early-stage dementia: study protocol for a multi-centre single-blind randomised controlled trial (GREAT)

Trials ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 152 ◽  
Author(s):  
Linda Clare ◽  
Antony Bayer ◽  
Alistair Burns ◽  
Anne Corbett ◽  
Roy Jones ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Study Protocol ◽  
Cognitive Rehabilitation ◽  
Early Stage ◽  
Controlled Trial ◽  
Randomised Controlled ◽  
Single Blind

HESTAT: Study protocol for a phase II/III, randomized, placebo-controlled, single blind study to evaluate the new hemostatic agent TT-173 in total knee arthroplasty

2017 ◽  
Vol 61 ◽  
pp. 16-22
Author(s):  
Aránzazu Gonzalez-Osuna ◽  
Sebastián Videla ◽  
Esther Cánovas ◽  
Gerard Urrútia ◽  
Santiago Rojas ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Phase Ii ◽  
Study Protocol ◽  
Knee Arthroplasty ◽  
Blind Study ◽  
Hemostatic Agent ◽  
Total Knee ◽  
Single Blind

Influence of Vitamin E on Plasma Malondialdehyde- Like Material in Man

1984 ◽  
Vol 51 (03) ◽  
pp. 347-348 ◽  
Author(s):  
C Cordova ◽  
A Musca ◽  
F Violi ◽  
C Alessandri ◽  
A Ghiselli ◽  
...  
Keyword(s):  
Vitamin E ◽  
Healthy Subjects ◽  
Placebo Treatment ◽  
Blind Study ◽  
Single Blind ◽  
Plasma Malondialdehyde

SummaryThe behaviour of plasma malondialdehyde-like material (MDA-LM) was evaluated in 13 healthy subjects by a single-blind study that consisted of placebo (30 days), vitamin E treatment (300 mg/day) (30 days) and placebo (30 days). The study demonstrated that MDA-LM did not change during placebo treatment while it significantly decreased after vitamin E administration.

Diagnostics of metal samples using the results of experimental and theoretical study of positively charged microparticles formed upon sample destruction

2018 ◽  
Vol 84 (10) ◽  
pp. 23-28
Author(s):  
D. A. Golentsov ◽  
A. G. Gulin ◽  
Vladimir A. Likhter ◽  
K. E. Ulybyshev
Keyword(s):  
Experimental Data ◽  
Early Stage ◽  
Experimental Studies ◽  
Material Model ◽  
Total Charge ◽  
Cross Sectional ◽  
Practical Applications ◽  
Mechanical And Electrical Properties ◽  
Order Of Magnitude ◽  
Using Data

Destruction of bodies is accompanied by formation of both large and microscopic fragments. Numerous experiments on the rupture of different samples show that those fragments carry a positive electric charge. his phenomenon is of interest from the viewpoint of its potential application to contactless diagnostics of the early stage of destruction of the elements in various technical devices. However, the lack of understanding the nature of this phenomenon restricts the possibility of its practical applications. Experimental studies were carried out using an apparatus that allowed direct measurements of the total charge of the microparticles formed upon sample rupture and determination of their size and quantity. The results of rupture tests of duralumin and electrical steel showed that the size of microparticles is several tens of microns, the particle charge per particle is on the order of 10–14 C, and their amount can be estimated as the ratio of the cross-sectional area of the sample at the point of discontinuity to the square of the microparticle size. A model of charge formation on the microparticles is developed proceeding from the experimental data and current concept of the electron gas in metals. The model makes it possible to determine the charge of the microparticle using data on the particle size and mechanical and electrical properties of the material. Model estimates of the total charge of particles show order-of-magnitude agreement with the experimental data.

Prospective Double-Blind Study of Zidovudine in Early Stage HIV infection

1991 ◽  
Author(s):  
Shannon M. Harrison
Keyword(s):  
Hiv Infection ◽  
Early Stage ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind

scholarly journals A survey of coping strategies among clinical nurses in China during the early stage of coronavirus disease 2019 pandemic: A cross‐sectional study

Nursing Open ◽  
2021 ◽  
Author(s):  
Jiao Tang ◽  
You Zhang ◽  
Fangfang Xiong ◽  
Fuying Li ◽  
Zehong Zheng ◽  
...  
Keyword(s):  
Coping Strategies ◽  
Early Stage ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Clinical Nurses

scholarly journals Correction to: Study protocol and rationale of the “Cogniaction project” a cross-sectional and randomized controlled trial about physical activity, brain health, cognition, and educational achievement in schoolchildren

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Patricio Solis-Urra ◽  
Jorge Olivares-Arancibia ◽  
Ernesto Suarez-Cadenas ◽  
Javier Sanchez-Martinez ◽  
Fernando Rodríguez-Rodríguez ◽  
...  
Keyword(s):  
Physical Activity ◽  
Randomized Controlled Trial ◽  
Study Protocol ◽  
Educational Achievement ◽  
Controlled Trial ◽  
Brain Health ◽  
Cross Sectional ◽  
Randomized Controlled ◽  
Health Cognition

scholarly journals Costs of Early Stage Alzheimer’s Disease in the United States: Cross-Sectional Analysis of a Prospective Cohort Study (GERAS-US)1

2020 ◽  
Vol 75 (2) ◽  
pp. 437-450
Author(s):  
Rebecca L. Robinson ◽  
Dorene M. Rentz ◽  
Jeffrey Scott Andrews ◽  
Anthony Zagar ◽  
Yongin Kim ◽  
...  
Keyword(s):  
United States ◽  
Alzheimer’S Disease ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Early Stage ◽  
The United States ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

scholarly journals Effect of number of medications and use of potentially inappropriate medications on frailty among early-stage older outpatients

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Yuya Uragami ◽  
Kazuhiro Takikawa ◽  
Hajime Kareki ◽  
Koji Kimura ◽  
Kazuyuki Yamamoto ◽  
...  
Keyword(s):  
Early Stage ◽  
Linear Trend ◽  
Cross Sectional Study ◽  
Potentially Inappropriate Medications ◽  
Sectional Study ◽  
Antithrombotic Drugs ◽  
Cross Sectional ◽  
The Relationship ◽  
Inappropriate Medications ◽  
Frailty Score

Abstract Background Frailty is an urgent concern among an aging population worldwide. However, the relationship between frailty and number and types of medications has not been studied in detail among early-stage older patients, and it is unclear what prescriptions may have a role in preventing frailty. This study aimed to clarify the effects of number of medications and use of potentially inappropriate medications (PIMs) on frailty among early-stage older outpatients in Japan. Methods A cross-sectional study was undertaken. Frailty scores and medications of outpatients aged 65–74 years who regularly visited community pharmacies were investigated. Frailty scores were classified as 0 (non-frailty), 1–2 (pre-frailty), and ≥ 3 (frailty). The association between frailty and number of medications was analyzed by age and compared between PIM use and non-use groups. The proportion of patients who used PIMs was also analyzed by frailty score. Results Of 923 older outpatients, 49 (5.3%) and 318 (34.5%) patients had frailty and pre-frailty scores, respectively. The numbers of medications among patients with pre-frailty and frailty were significantly higher than among those with non-frailty (p <  0.001 for both). A similar increase was shown for PIM use groups aged 69–71 and 72–74 years, but not for the PIM use group aged 65–68 years and all groups without PIM use. An increasing linear trend was observed for the relationship between the proportion of patients who used any PIM, as well as some subcategories of PIMs (such as NSAIDs, benzodiazepines, loop diuretics and antithrombotic drugs) and frailty score. Conclusions Unnecessary medication use among early-stage older outpatients, especially patients aged ≥69 years who use PIMs and many medications, seems to be associated with frailty, but further research is needed to confirm these findings.

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