scholarly journals Cell cycle kinetic dysregulation in HIV-infected normal lymphocytes

2005 ◽  
Vol 66A (1) ◽  
pp. 41-51 ◽  
Author(s):  
David M. Asmuth ◽  
Nan Wang ◽  
Ying Lu ◽  
Xiao-Dong Li ◽  
Lisa Reece ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Kinetic

Cell Cycle Kinetic Effects of Tamoxifen on Human Breast Cancer Cells.

1993 ◽  
Vol 698 (1 Breast Cancer) ◽  
pp. 174-181 ◽  
Author(s):  
MARCO DANOVA ◽  
CARLO PELLICCIARI ◽  
CARLO ZIBERA ◽  
ROSANNA MANGIAROTTI ◽  
NADIA GIBELLI ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Cell Cycle Kinetic ◽  
Kinetic Effects

Cell cycle kinetic analysis with flow cytometry in pea root meristem synchronized with aphidicolin

1991 ◽  
Vol 81 (4) ◽  
pp. 507-512 ◽  
Author(s):  
Sergio Sgorbati ◽  
Elio Sparvoli ◽  
Marisa Levi ◽  
Maria Grazia Galli ◽  
Sandra Citterio ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Flow Cytometry ◽  
Kinetic Analysis ◽  
Root Meristem ◽  
Cell Cycle Kinetic ◽  
Pea Root

scholarly journals Cell Cycle Kinetic Analysis of Colorectal Neoplasms Using a New Automated Immunohistochemistry-Based Cell Cycle Detection Method

Medicine ◽  
2015 ◽  
Vol 94 (4) ◽  
pp. e501 ◽  
Author(s):  
Ayako Tomono ◽  
Tomoo Itoh ◽  
Emmy Yanagita ◽  
Naoko Imagawa ◽  
Yoshihiro Kakeji
Keyword(s):  
Cell Cycle ◽  
Kinetic Analysis ◽  
Colorectal Neoplasms ◽  
Detection Method ◽  
Cell Cycle Kinetic ◽  
Cycle Detection

scholarly journals Cell cycle kinetic measurements in an irradiated rat rhabdomyosarcoma using a monoclonal antibody to bromodeoxyuridine

Cytometry ◽  
1985 ◽  
Vol 6 (6) ◽  
pp. 611-619 ◽  
Author(s):  
Michael Nüsse ◽  
S. M. Javed Afzal ◽  
Betsy Carr ◽  
Kris Kavanau
Keyword(s):  
Cell Cycle ◽  
Monoclonal Antibody ◽  
Kinetic Measurements ◽  
Cell Cycle Kinetic

Cell cycle kinetic analysis with flow cytometry in pea root meristem synchronized with aphidicolin

1991 ◽  
Vol 81 (4) ◽  
pp. 507-512 ◽  
Author(s):  
Sergio Sgorbati ◽  
Elio Sparvoli ◽  
Marisa Levi ◽  
Maria Grazia Galli ◽  
Sandra Citterio ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Flow Cytometry ◽  
Kinetic Analysis ◽  
Root Meristem ◽  
Cell Cycle Kinetic ◽  
Pea Root

Maytansine-Induced Mitotic Arrest in Human Lymphoblasts

1977 ◽  
Vol 35 ◽  
pp. 460-461
Author(s):  
Tai-Te Chao ◽  
John Sullivan ◽  
Awtar Krishan
Keyword(s):  
Electron Microscopy ◽  
Cell Cycle ◽  
Transmission Electron Microscopy ◽  
Tubulin Polymerization ◽  
Vinca Alkaloids ◽  
Antimitotic Activity ◽  
Transmission Electron ◽  
Flow Microfluorometry ◽  
Brain Tubulin

Maytansine, a novel ansa macrolide (1), has potent anti-tumor and antimitotic activity (2, 3). It blocks cell cycle traverse in mitosis with resultant accumulation of metaphase cells (4). Inhibition of brain tubulin polymerization in vitro by maytansine has also been reported (3). The C-mitotic effect of this drug is similar to that of the well known Vinca- alkaloids, vinblastine and vincristine. This study was carried out to examine the effects of maytansine on the cell cycle traverse and the fine struc- I ture of human lymphoblasts.Log-phase cultures of CCRF-CEM human lymphoblasts were exposed to maytansine concentrations from 10-6 M to 10-10 M for 18 hrs. Aliquots of cells were removed for cell cycle analysis by flow microfluorometry (FMF) (5) and also processed for transmission electron microscopy (TEM). FMF analysis of cells treated with 10-8 M maytansine showed a reduction in the number of G1 cells and a corresponding build-up of cells with G2/M DNA content.

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