Assessment of the impact of kinetic effect of ion parallel heat conduction on DEMO relevant SOL plasma using integrated SOL-divertor code SONIC

In plasmas of relatively lower collisionality, such as scrape-off layer (SOL) of fusion tokamak device, parallel heat conductivity of plasma ion becomes smaller than expected by the classical Spitzer-Harm model due to nonlocal kinetic effect. We have assessed, by simulation, impact and role of such kinetic effect of ion heat conductivity (abbreviated by ion KE in this paper) on DEMO relevant tokamak SOL plasma, supposing Japanese demonstration tokamak reactor concept JA DEMO. A series of test simulation, where the ion KE is modeled by a widely used Free-streaming energy (FSE) limited model, has demonstrated the following significant impact of the ion KE on JA DEMO SOL plasma at the baseline operation scenario: (1) the ion KE decreases the ion parallel heat flux density around X-point and further upstream of low field side (LFS) area along the separatrix, where the parallel collisionality tends to decrease due to combination of higher temperature, lower density (i.e. longer mean free path of ion collisions) and higher temperature gradient (shorter characteristic length). Up to 40-60 % of decrease, compared to the case w/o ion KE, is observed among the tested cases where the ion KE level, specified by parameter αi in the FSE-limited model, is scanned over the possible range 0.2 < αi < 2.0. (2) The ion KE leads to significant increase in the ion temperature Ti (up to 600 % of increase among the tested cases) and significant decrease in the ion density ni (up to -80 % of decrease among the tested cases), widely over SOL upstream. By energy balance analysis, it has been suggested that the ion KE affects the upstream ni and Ti, respectively by power of 0.4 and -0.4 of the flux limiting factor, around the separatrix upstream as far as spatial change in plasma parameters are moderate. The results of this study serve as a fundamental assessment of the ion KE for DEMO relevant SOL plasma, clarifying the need of further sophistication of the modeling toward quantitaive prediction.

Emergence of Many Mini-Circles from a Coffee Suspension with Mechanical Rotation

Drying of an aqueous suspension containing fine granules leads to the formation of a circular pattern, i.e., the coffee-ring effect. Here, we report the effect of mechanical rotation with drying of an aqueous suspension containing a large amount of granular particles as in the Turkish coffee. It was found that wavy fragmented stripes, or a “waggly pattern”, appear in the early stage of the drying process and a “polka-dot pattern” with many small circles is generated in the late stage. We discuss the mechanism of these patterns in terms of the kinetic effect on micro phase-segregation. We suggest that the waggly pattern is induced through a mechanism similar to spinodal decomposition, whereas polka-dot formation is accompanied by the enhanced segregation of a water-rich phase under mechanical rotation.

Effect of nitrogen-containing bisphosphonates on osteoclasts and osteoclastogenesis: an ultrastructural study

We have previously indicated that a single injection of alendronate, one of the nitrogen-containing bisphosphonates (NBPs), affects murine hematopoietic processes, such as the shift of erythropoiesis from bone marrow (BM) to spleen, disappearance of BM-resident macrophages, the increase of granulopoiesis in BM and an increase in the number of osteoclasts. NBPs induce apoptosis and the formation of giant osteoclasts in vitro and/or in patients undergoing long-term NBP treatment. Therefore, the time-kinetic effect of NBPs on osteoclasts needs to be clarified. In this study, we examined the effect of alendronate on mouse osteoclasts and osteoclastogenesis. One day after the treatment, osteoclasts lost the clear zone and ruffled borders, and the cell size decreased. After 2 days, the cytoplasm of osteoclasts became electron dense and the nuclei became pyknotic. Some of the cells had fragmented nuclei. After 4 days, osteoclasts had euchromatic nuclei attached to the bone surface. Osteoclasts had no clear zones or ruffled borders. After 7 days, osteoclasts formed giant osteoclasts via the fusion of multinuclear and mononuclear osteoclasts. These results indicate that NBPs affect osteoclasts and osteoclastogenesis via two different mechanisms.

Transhydrogenation of pentane with 1,5- and 2,4-hexadiene over CrOx/Al2O3

Transhydrogenation of pentane (P) and 1,5-hexadiene (1,5HD) and pentane and 2,4-hexadiene (2,4HD) was studied over a CrOx/alumina catalyst at 523–773 K. Thermodynamic stability differences between the conjugated (2,4-hexadiene) and non-conjugated (1,5-hexadiene) isomers indicated that transhydrogenation was favoured between pentane and 1,5-hexadiene but not pentane and 2,4-hexadiene (+ ve ∆G). At 773 K a significantly enhanced alkene yield was observed for the P/1,5HD system, clearly showing the effect of transhydrogenation. The yield of alkenes was ~ 50% and included alkylated and isomerized alkenes. Alkylation and isomerization were significant reactions under reaction conditions. Pentane was shown to affect the chemistry of 1,5HD and vice versa with the conversion of pentane significantly enhanced at all reaction temperatures, indicating a molecular interaction between the reactants even when transhydrogenation was not obvious. In contrast, no effect on the conversion of pentane was observed when the co-feed was 2,4HD. An unexpected effect of pentane on 2,4HD conversion was observed, with all reactions of cis-2,4-hexadiene (including alkylation and isomerization) being completely inhibited at low reaction temperatures (573 K and 523 K) by the presence of pentane, suggesting that pentane competes for the same sites as cis-2,4-hexadiene. Transhydrogenation activity between pentane and 1,5-hexadiene was less obvious at the lower reaction temperature, which appeared to be a kinetic effect. Direct hydrogenation of 1,5-hexadiene revealed that 1,5HD sampled the same hydrogen population for hydrogenation and transhydrogenation. Comparisons of transhydrogenation of 1-hexyne, 1,5-hexadiene, and 2,4-hexadiene with pentane have revealed significant differences in the adsorption and reaction chemistry of the three isomers.

Experimental study on the kinetic effect of N-butyl-N-methylpyrrolidinium tetrafluoroborate and poly(N-vinyl-caprolactam) on CH4 hydrate formation

The kinetic inhibition performance of N-butyl-N-methylpyrrolidinium tetrafluoroborate ([BMP][BF4]), poly(N-vinylcaprolactam) (PVCap) and compound inhibitor systems on methane hydrate were studied from both macroscopic and microscopic perspectives.