Different apoptotic effects of wogonin via induction of H2O2 generation and Ca2+ overload in malignant hepatoma and normal hepatic cells

2010 ◽  
Vol 111 (6) ◽  
pp. 1629-1641 ◽  
Author(s):  
Libin Wei ◽  
Na Lu ◽  
Qinsheng Dai ◽  
Jingjing Rong ◽  
Yan Chen ◽  
...  
Keyword(s):  
Hepatic Cells ◽  
H2o2 Generation ◽  
Malignant Hepatoma ◽  
Apoptotic Effects

Hepatic Ultrastructure Changes Induced by Lithocholic Acid

1967 ◽  
Vol 25 ◽  
pp. 162-163 ◽  
Author(s):  
F. G. Zaki
Keyword(s):  
Endoplasmic Reticulum ◽  
Lithocholic Acid ◽  
Smooth Endoplasmic Reticulum ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Electron Microscopic ◽  
Hydropic Degeneration ◽  
Hepatic Cells ◽  
Low Protein ◽  
Microscopic Studies

Addition of lithocholic acid (LCA), a naturally occurring bile acid in mammals, to a low protein diet fed to rats induced marked inflammatory reaction in the hepatic cells followed by hydropic degeneration and ductular cell proliferation. These changes were accompanied by dilatation and hyperplasia of the common bile duct and formation of “gallstones”. All these changes were reversible when LCA was withdrawn from the low protein diet except for the hardened gallstones which persisted.Electron microscopic studies revealed marked alterations in the hepatic cells. Early changes included disorganization, fragmentation of the rough endoplasmic reticulum and detachment of its ribosomes. Free ribosomes, either singly or arranged in small clusters were frequently seen in most of the hepatic cells. Vesiculation of the smooth endoplasmic reticulum was often encountered as early as one week after the administration of LCA (Fig. 1).

Discovery of intracellular 2,8 dihydroxyadenine crystals in bovine lymphatic and hepatic cells

1987 ◽  
Vol 45 ◽  
pp. 906-907
Author(s):  
W. E. Rigsby ◽  
D. M. Hinton ◽  
V. J. Hurst ◽  
P. C. McCaskey
Keyword(s):  
Polarized Light ◽  
Paraffin Sections ◽  
Tissue Samples ◽  
Whole Cells ◽  
Tissue Sections ◽  
Hepatic Cells ◽  
Slaughter House ◽  
Mammalian Tissues ◽  
Carbon Coated ◽  
Cellular Components

Crystalline intracellular inclusions are rarely seen in mammalian tissues and are often difficult to positively identify. Lymph node and liver tissue samples were obtained from two cows which had been rejected at the slaughter house due to the abnormal appearance of these organs in the animals. The samples were fixed in formaldehyde and some of the fixed material was embedded in paraffin. Examination of the paraffin sections with polarized light microscopy revealed the presence of numerous crystals in both hepatic and lymph tissue sections. Tissue sections were then deparaffinized in xylene, mounted, carbon coated, and examined in a Phillips 505T SEM equipped with a Tracor Northern X-ray Energy Dispersive Spectroscopy (EDS) system. Crystals were obscured by cellular components and membranes so that EDS spectra were only obtainable from whole cells. Tissue samples which had been fixed but not paraffin-embedded were dehydrated, embedded in Spurrs plastic, and sectioned.

Letter: Leser-Trelat sign with porphyria cutanea tarda and malignant hepatoma

1976 ◽  
Vol 112 (5) ◽  
pp. 730b-730 ◽  
Author(s):  
C. I. Harrington
Keyword(s):  
Porphyria Cutanea Tarda ◽  
Malignant Hepatoma

Hypericin is an encouraging new photosensitizer for photodynamic therapy of esophageal dysplasia/cancer: Antiproliferative and apoptotic effects

2001 ◽  
Vol 120 (5) ◽  
pp. A443-A443
Author(s):  
M LENZ ◽  
M HOEPFNER ◽  
A THEISS ◽  
B LAMPE ◽  
H KASHTAN ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Esophageal Dysplasia ◽  
Apoptotic Effects

Demonstration of the Effect of Oral Fat without Choline within One Hour on Centrolobular Hepatic Cells of the Rat

1960 ◽  
Vol 39 (6) ◽  
pp. 758-763 ◽  
Author(s):  
Eduardo A. Porta ◽  
W. Stanley Hartroft
Keyword(s):  
Hepatic Cells

Apoptotic Effects of Dichloro Stearic and Dichloro Myristic Acid in Human Hepatoma Cells (HepG2)

2001 ◽  
Vol 89 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Einar Lystad ◽  
Arne T. Hostmark ◽  
Einar Jebens
Keyword(s):  
Myristic Acid ◽  
Hepatoma Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Cells ◽  
Apoptotic Effects

Persistence of HCV in quiescent hepatic cells under conditions of an interferon-induced antiviral response

2013 ◽  
Vol 51 (01) ◽  
Author(s):  
O Bauhofer ◽  
A Ruggieri ◽  
B Schmid ◽  
P Schirmacher ◽  
R Bartenschlager
Keyword(s):  
Antiviral Response ◽  
Hepatic Cells

Extracts from the marine fungus Neosartorya tsunodae and the soil fungus Neosartorya fischeri exhibit anti-proliferative and pro-apoptotic effects in human cancer cell lines

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
B Castro-Carvalho ◽  
A Ramos ◽  
M Prata-Sena ◽  
T Dethoup ◽  
S Buttachon ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Soil Fungus ◽  
Cancer Cell Lines ◽  
Marine Fungus ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Neosartorya Fischeri ◽  
Apoptotic Effects

Antiproliferative and apoptotic effects of wheatgrass (Triticum aestivum L.) extracts on chronic myeloid leukemia (CML) cell line

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
A Karadag ◽  
T Ozkan ◽  
B Altınok ◽  
S Aydos ◽  
A Sunguroglu
Keyword(s):  
Triticum Aestivum ◽  
Chronic Myeloid Leukemia ◽  
Cell Line ◽  
Myeloid Leukemia ◽  
Triticum Aestivum L ◽  
Apoptotic Effects
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