Relationship Between Chemical Composition and Biological Function of Pseudomonas aeruginosa Lipopolysaccharide: Effect on Human Neutrophil Chemotaxis and Oxidative Burst

1991 ◽  
Vol 49 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Arsalan Kharazmi ◽  
Anders Fomsgaard ◽  
Robert S. Conrad ◽  
Chris Galanos ◽  
Niels Høiby
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Chemical Composition ◽  
Oxidative Burst ◽  
Human Neutrophil ◽  
Biological Function ◽  
Neutrophil Chemotaxis

Chemical Composition and Antibacterial Activity of Essential Oils of Three Medicinal Plants from Algerian Semi-Arid Climatic Zone

2018 ◽  
Vol 16 (S1) ◽  
pp. S155-S163 ◽  
Author(s):  
S. Mehalaine ◽  
O. Belfadel ◽  
T. Menasria ◽  
A. Messaili
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Rosmarinus Officinalis ◽  
Salvia Officinalis ◽  
Thymus Algeriensis

The present study was carried out to determine, for the first time, the chemical composition and antibacterial activity of essential oils derived from the aerial parts of three aromatic plants Thymus algeriensis Boiss & Reut, Rosmarinus officinalis L., and Salvia officinalis L. growing under semiarid conditions. The essential oils were chemically analyzed and identified by gas chromatography (GC) and GC/ mass spectrometry (GC/MS) and their antimicrobial activity was individually evaluated against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa using both agar disk diffusion and agar dilution methods. The major constituents of Thymus algeriensis essential oil were identified as camphor (13.62%), 1,8-cineol (6.00%), borneol (5.74%), viridiflorol (4.00%), and linalool (3.93%). For Rosmarinus officinalis essential oil, 48 compounds were characterized, of which the main constituents were camphor (17.09%), Z-β-ocimene (10.88%), isoborneol (9.68%), α-bisabolol (7.89%), and borneol (5.11%). While, Salvia officinalis essential oil was characterized by β-thujone (16.44%), followed by viridiflorol (10.93%), camphor (8.99%), 1,8-cineol (8.11%), trans-caryophyllene (5.85%), and α-humulene (4.69%) as the major components. Notably, results from antibacterial screening indicated that Thymus algeriensis and Salvia officinalis essential oils exhibited a strong inhibitory effect against both Escherichia coli and Staphylococcus aureus compared to Rosmarinus officinalis essential oil. Further, less activity was recorded against Pseudomonas aeruginosa for the three tested essential oils.

scholarly journals EFFECT OF METHYL-PREDNISOLONF. AND POLYMIXIN B-SULPHATE ON ENDOTOXIN INDUCED INHIBITION OF HUMAN NEUTROPHIL CHEMOTAXIS

1977 ◽  
Vol 11 (4) ◽  
pp. 501-501
Author(s):  
Andrew C Issekutz ◽  
Matilda Ng ◽  
W Douglas Biggar ◽  
A Sass-Kortsak
Keyword(s):  
Human Neutrophil ◽  
Neutrophil Chemotaxis

scholarly journals Role of secretory events in modulating human neutrophil chemotaxis.

1978 ◽  
Vol 62 (6) ◽  
pp. 1364-1374 ◽  
Author(s):  
J I Gallin ◽  
D G Wright ◽  
E Schiffmann
Keyword(s):  
Human Neutrophil ◽  
Neutrophil Chemotaxis

scholarly journals Phytochemical Screening, Chemical Composition and Antimicrobial Activity of Cinnamon verum Bark

2020 ◽  
pp. 36-43
Author(s):  
Hamza Mohamed Ahmed ◽  
Ashraf Mahmoud Ramadhani ◽  
Ibrahim Yaagoub Erwa ◽  
Omer Adam Omer Ishag ◽  
Mohamed Bosharh Saeed
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Phytochemical Screening ◽  
High Concentration ◽  
Standard Methods ◽  
Crude Extracts ◽  
Acetone Extracts

cinnamon dating from 1000 AD when it was firstly recorded in English due to its important as aroma and as herbs. The aim of this study was to investigate phytochemicals constitutes, chemical composition and antimicrobial activity of the essential oil of commercial samples of Cinnamon verum bark. The essential oil was extracted by hydrodistillation, while the crude extracts were prepared by three different solvents methanol (70%), acetone and aqueous. Phytochemical screening of crude extracts was performed using standard methods. The essential oil was subjected to GC-MS analysis and tested against Staphylococcus aureus, Salmonella typhimurium, Pseudomonas aeruginosa, Eschericchia coli and Candida albicans. The obtained results indicated the presence of alkaloids, flavonoids, coumarin, tannins, terpenoids, saponin, glycoside, anthrocyanin and phenolic compounds in the methanolic, aqoueous and acetone extracts of C. verum bark; while the major components of the extracted essential oil of C. verum bark were cinnamaldehyde (85.50%), stigmasterol (3.69%), Cadinene (1.37%), (E)-cinnamaldehyde (1.35%), alpha-amorphene (1.33%), hydrocinnamaldehyde (1.28%), alpha-cubebene (1.25) and ergosterol (1.09%) respectively. The antimicrobial activity result indicated the high activity of the extracted essential oil against all tested microorganisms at high concentration; except in S. typhimurium and C. albicans at concentrations of 25% and 12.5% no activity was noticed. Based in our obtained results the essential oil of C. verum bark had high potential as antimicrobial agent, therefore, recommended for more advanced studies to be conducted on this abundant plant as natural source of antibiotics.

scholarly journals Binding and Spreading of ParB on DNA Determine Its Biological Function in Pseudomonas aeruginosa

2011 ◽  
Vol 193 (13) ◽  
pp. 3342-3355 ◽  
Author(s):  
M. Kusiak ◽  
A. Gapczynska ◽  
D. Plochocka ◽  
C. M. Thomas ◽  
G. Jagura-Burdzy
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Biological Function
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