Macrophage inflammatory protein 1-? mRNA expression in an immortalized microglial cell line and cortical astrocyte cultures

1995 ◽  
Vol 40 (6) ◽  
pp. 755-763 ◽  
Author(s):  
Greer Murphy ◽  
X.-C. Jia ◽  
Y. Song ◽  
E. Ong ◽  
R. Shrivastava ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Cell Line ◽  
Microglial Cell ◽  
Inflammatory Protein ◽  
Cortical Astrocyte ◽  
Microglial Cell Line ◽  
Macrophage Inflammatory Protein

Leukemia inhibitory factor mRNA is expressed in cortical astrocyte cultures but not in an immortalized microglial cell line

1995 ◽  
Vol 184 (1) ◽  
pp. 48-51 ◽  
Author(s):  
Greer M Murphy ◽  
Yaoli Song ◽  
Elisa Ong ◽  
Yuen Ling Lee ◽  
Karen G Schraidt ◽  
...  
Keyword(s):  
Cell Line ◽  
Leukemia Inhibitory Factor ◽  
Microglial Cell ◽  
Inhibitory Factor ◽  
Cortical Astrocyte ◽  
Microglial Cell Line

scholarly journals Signaling of Macrophage Inflammatory Protein (MIP)-3β Facilitates Dengue Virus-Induced Microglial Cell Migration

Viruses ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 690
Author(s):  
Ming-Kai Jhan ◽  
Ting-Jing Shen ◽  
Po-Chun Tseng ◽  
Yung-Ting Wang ◽  
Chiou-Feng Lin
Keyword(s):  
Cell Migration ◽  
Dengue Virus ◽  
Viral Entry ◽  
Cell Activation ◽  
Microglial Cell ◽  
Inflammatory Protein ◽  
Infected Cells ◽  
Chemotactic Factors ◽  
And Migration ◽  
Macrophage Inflammatory Protein

The infection by dengue virus (DENV) of microglia causes cell activation and migration via a mechanism involving viral entry, RNA release, and Toll-like receptor 3 signaling. In this study, we demonstrated that secreted chemotactic factors present in microglial conditioned medium (MCM) facilitated cell motility in the murine BV2 microglial cells. The pharmacological disruption of lipid rafts/caveolae reduced DENV- and ultraviolet (UV)-inactivated MCM-induced microglial cell migration. An antibody-based cytokine/chemokine array showed an increase in macrophage inflammatory protein (MIP)-3β in MCM produced using DENV-infected cells. The pharmacological inhibition of c-Jun N-terminal kinase (JNK) retarded UV-MCM-induced microglial cell migration. These results demonstrate that secreted MIP-3β and its effect on the JNK signaling pathways mediates DENV-induced BV2 microglial cell migration.

scholarly journals Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2

PLoS ONE ◽  
2019 ◽  
Vol 14 (9) ◽  
pp. e0222861 ◽  
Author(s):  
Shuji Shimoyama ◽  
Tomonori Furukawa ◽  
Yoshiki Ogata ◽  
Yoshikazu Nikaido ◽  
Kohei Koga ◽  
...  
Keyword(s):  
Cell Line ◽  
Microglial Cell ◽  
Translocator Protein ◽  
Microglial Cell Line ◽  
Translocator Protein 18 Kda

Effect of ammonia on endocytosis, cytokine production and lysosomal enzyme activity of a microglial cell line

1994 ◽  
Vol 145 (4) ◽  
pp. 277-288 ◽  
Author(s):  
C.L. Atanassov ◽  
C.D. Muller ◽  
S. Sarhan ◽  
B. Knödgen ◽  
G. Rebel ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Cell Line ◽  
Lysosomal Enzyme ◽  
Microglial Cell ◽  
Cytokine Production ◽  
Lysosomal Enzyme Activity ◽  
Microglial Cell Line
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