Both living and dead Faecalibacterium prausnitzii alleviate HDM ‐induced allergic asthma through the modulation of gut microbiota and short‐chain fatty acid ( SCFAs ) production

2021 ◽  
Author(s):  
Wenbing Hu ◽  
Wenwei Lu ◽  
Lingzhi Li ◽  
Hao Zhang ◽  
Yuan‐kun Lee ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Gut Microbiota ◽  
Allergic Asthma ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Faecalibacterium Prausnitzii

scholarly journals The use of disinfectant in barn cleaning alters microbial composition and increases carriage of Campylobacter jejuni in broiler chickens

2021 ◽  
Author(s):  
Yi Fan ◽  
Andrew Forgie ◽  
Tingting Ju ◽  
Camila Marcolla ◽  
Tom Inglis ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Gut Microbiota ◽  
Campylobacter Jejuni ◽  
Broiler Chicken ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Microbial Composition ◽  
Commercial Chicken ◽  
Cecal Microbiota

To maintain food safety and flock health in broiler chicken production, biosecurity approaches to keep chicken barns free of pathogens are important. Canadian broiler chicken producers must deep clean their barns with chemical disinfectants at least once annually (full disinfection; FD) and may wash with water (water-wash; WW) throughout the year. However, many producers use FD after each flock, assuming a greater efficacy of more stringent cleaning protocols, although little information is known regarding how these two cleaning practices affect pathogen population and gut microbiota. In the current study, a cross-over experiment over four production cycles was conducted in seven commercial chicken barns to compare WW and FD. We evaluated the effects of barn cleaning method on the commercial broiler performance, cecal microbiota composition, pathogen occurrence and abundance, as well as short-chain fatty acid concentrations in the month-old broiler gut. The 30-day body weight and mortality rate were not affected by the barn cleaning methods. The WW resulted in a modest but significant effect on the structure of broiler cecal microbiota (weighted-UniFrac; adonis p = 0.05, and unweighted-UniFrac; adonis p = 0.01), with notable reductions in Campylobacter jejuni occurrence and abundance. In addition, the WW group had increased cecal acetate, butyrate and total short-chain fatty acid concentrations, which were negatively correlated with C. jejuni abundance. Our results support the use of WW over FD to enhance the activity of the gut microbiota and potentially reduce zoonotic transmission of C. jejuni in broiler production without previous disease challenges.

scholarly journals Effect of a high-collagen peptide diet on the gut microbiota and short-chain fatty acid metabolism

2020 ◽  
Vol 75 ◽  
pp. 104278
Author(s):  
Fengfeng Mei ◽  
Zhouwei Duan ◽  
Muxue Chen ◽  
Jinfeng Lu ◽  
Meihui Zhao ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Gut Microbiota ◽  
Fatty Acid Metabolism ◽  
Short Chain Fatty Acid ◽  
Acid Metabolism ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Collagen Peptide

scholarly journals Herbs and Spices Modulate Gut Microbiota Composition: A Randomized, Crossover, Controlled-Feeding Study

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 360-360
Author(s):  
Kristina Petersen ◽  
Penny Kris-Etherton ◽  
Samantha Anderson ◽  
Jeremy Chen See ◽  
Connie Rogers ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Gut Microbiota ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Medical Institute ◽  
Microbiota Composition ◽  
Feeding Study ◽  
Gut Microbiota Composition ◽  
Herbs And Spices

Abstract Objectives The effect of culinary doses of herbs and spices, consumed as part of a well-defined dietary pattern, on gut microbiota composition has not been previously studied. The aim of this study was to examine gut microbial composition following an average American diet (carbohydrate: 50% kcal; protein: 17%; total fat: 33%; saturated fat: 11%; sodium: 3000 mg/d) containing herbs and spices at 0.5 (Low Spice Diet; LSD), 3.3 (Moderate Spice Diet; MSD) and 6.6 (High Spice Diet; HSD) g/day/2100 kcal in adults at-risk for cardiovascular disease (CVD). Methods Fifty-four adults (57% female; 45 ± 11 years, BMI 29.8 ± 2.9 kg/m2; waist circumference 102.8 ± 7.1 cm) were included in this three-period, randomized, crossover, controlled-feeding study. Each diet was provided for 4-weeks with a minimum 2-week wash-out period. At baseline and the end of each diet period subjects provided a fecal sample for 16S rRNA gene sequencing. QIIME2 was used for data filtration, sequence clustering, taxonomy assignment and statistical analysis. Linear discriminant analysis Effect Size (LEfSe) analyses were used to determine enriched biomarker taxa following each diet. Results No between-diet differences in alpha diversity were observed based on Faith's Phylogenetic Diversity, Observed Operational Taxonomic Units (OTUs), and Pielou's Evenness (Kruskal-Walllis, P > 0.05). Principal coordinate analysis showed beta-diversity following the HSD significantly differed from baseline (PERMANOVA, P = 0.030). LEfSe pairwise analyses identified multiple taxa that were differentially abundant following the spice-containing diets vs. baseline. Compared to baseline, 34 taxa were enriched with the HSD, 22 taxa were enriched with the MSD and 20 taxa were enriched with the LSD. Members of the taxa enriched with the HSD are known short-chain fatty acid producers (Faecalibacterium and Butyricimonas). Conclusions The addition of herbs and spices at 0.5, 3.3, and 6.6 g/day/2100 kcal to an average American diet altered gut microbiota composition, and resulted in enrichment of short-chain fatty acid producers, after 4-weeks in adults at elevated risk for CVD. Funding Sources McCormick Science Institute; NCATS NIH (1UL1TR002014–01); Grant from the Howard Hughes Medical Institute through the Precollege and Undergraduate Science Education Program to Juniata College supported the computational research.

scholarly journals Short-Chain Fatty Acids Reduced Renal Calcium Oxalate Stones by Regulating the Expression of Intestinal Oxalate Transporter SLC26A6

mSystems ◽  
2021 ◽  
Author(s):  
Yu Liu ◽  
Xi Jin ◽  
Yucheng Ma ◽  
Zhongyu Jian ◽  
Zhitao Wei ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Gut Microbiota ◽  
Calcium Oxalate ◽  
Renal Stone ◽  
Short Chain Fatty Acid ◽  
Short Chain Fatty Acids ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Healthy Controls

Some studies found that the relative abundances of short-chain-fatty-acid (SCFA)-producing bacteria were lower in the gut microbiota of renal stone patients than healthy controls. Our previous study demonstrated that SCFAs could reduce the formation of renal calcium oxalate (CaOx) stones, but the mechanism is still unknown.

Sign in / Sign up

Export Citation Format

Share Document