Selective extraction of bisphenol A from water by one-monomer molecularly imprinted magnetic nanoparticles

A molecularly imprinted polymer (MIP) for highly selective solid-phase extraction (SPE) of bisphenol A (BPA) was prepared using phenolphthalein (PP) as the novel dummy template by bulk polymerization. A particle diameter distribution of 40–60 μm, a specific surface area of 359.8 m2·g−1, and a total pore volume of 0.730 cm3·g−1 for the prepared PP-imprinted polymer (PPMIP) were obtained. Good selectivity and specific adsorption capacity for BPA of the prepared PPMIP were also demonstrated by the chromatographic evaluation and sorption experiments. The PPMIP as a SPE sorbent was evaluated for the selective extraction and clean-up of BPA from complex biological, environmental, and food samples. Meanwhile, an accurate and sensitive analytical method based on the PPMIP-SPE purification procedure coupled with high performance liquid chromatography-diode array detector (HPLC-DAD) detection has been successfully developed for the rapid determination of BPA from these samples, with detection limits of 1.3 ng·mL−1 for bovine serum and milk, 2.6 ng·mL−1 for human urine and edible oil, 5.2 ng·mL−1 for soybean sauce, and 1.3 ng·g−1 for sediment. The BPA recoveries at two different spiking levels were in the range of 82.1–106.9%, with relative standard deviation (RSD) values below 7.7%.

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Preparation of molecularly imprinted polymers based on magnetic nanoparticles for the selective extraction of protocatechuic acid from plant extracts

Journal of Separation Science ◽

10.1002/jssc.201401142 ◽

2015 ◽

Vol 38 (6) ◽

pp. 1046-1052 ◽

Cited By ~ 21

Author(s):

Xiaoyu Xie ◽

Fen Wei ◽

Liang Chen ◽

Sicen Wang

Keyword(s):

Magnetic Nanoparticles ◽

Plant Extracts ◽

Molecularly Imprinted Polymers ◽

Protocatechuic Acid ◽

Selective Extraction ◽

Molecularly Imprinted ◽

Imprinted Polymers

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Application of Molecular Imprinted Polymers for Selective Solid Phase Extraction of Bisphenol A

Ecological Chemistry and Engineering S ◽

10.1515/eces-2016-0046 ◽

2016 ◽

Vol 23 (4) ◽

pp. 651-664 ◽

Cited By ~ 1

Author(s):

Anna Poliwoda ◽

Małgorzata Mościpan ◽

Piotr P. Wieczorek

Keyword(s):

Bisphenol A ◽

Solid Phase Extraction ◽

Methacrylic Acid ◽

Solid Phase ◽

Selective Extraction ◽

Phase Extraction ◽

Aqueous Samples ◽

Molecularly Imprinted ◽

Imprinted Polymers ◽

Relative Standard

Abstract Selective molecularly imprinted polymers (MIPs) with bisphenol A as template were synthesized using the non-covalent imprinting approach. MIPs were prepared using thermally initiated polymerization with 1,1’-azobis(cyclohexanecarbonitryle) (ACHN) as initiator and ethylene glycol dimethacrylate (EDMA) as a cross-linking agent. The tested functional monomers included methacrylic acid, acrylamide, and 4-vinylpyridine. The selectivity of the BPA-MIP for the solid phase extraction of bisphenol A was tested in samples containing other related alkylphenols. The polymers prepared in acetonitrile using methacrylic acid or acrylamide as monomer showed the highest selectivity towards target analyte (the selectivity ratio 8:1, respectively for MIP and NIP). The proposed procedure has been proven to be an effective for selective extraction of bisphenol A in aqueous samples (recoveries over 85%) enabling detection and quantification limits of 25 and 70 μg/dm3, respectively based on 10 cm3 of sample volume, with relative standard deviations (RSD) lower than 6%. The obtained molecularly imprinted material showed interesting properties for selective extraction and preconcentration of studied analyte from large volumes of aqueous samples without any problems of cartridge clogging.

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