A Role of Aging in the Progression of Cortical Excitability in Benign Adult Familial Myoclonus Epilepsy type 1 Patients

2021 ◽  
Author(s):  
Shuichiro Neshige ◽  
Takefumi Hitomi ◽  
Maya Tojima ◽  
Kazuki Oi ◽  
Katsuya Kobayashi ◽  
...  
Keyword(s):  
Cortical Excitability ◽  
Myoclonus Epilepsy

scholarly journals Possible Mechanisms by which Stefin B could Regulate Proteostasis and Oxidative Stress

Cells ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 70 ◽  
Author(s):  
Eva Žerovnik
Keyword(s):  
Oxidative Stress ◽  
Protease Inhibitor ◽  
Protein Aggregates ◽  
Misfolded Proteins ◽  
Progressive Myoclonus Epilepsy ◽  
The Family ◽  
Myoclonus Epilepsy ◽  
And Oxidative Stress

Human stefin B is a protease inhibitor from the family of cystatins. It was reported that it forms oligomers in cells. We have shown that it has a role in cell’s response to misfolded proteins. We also have shown that its oligomers bind amyloid-beta (Aβ). Here, we discuss ways, how stefin B could reduce build-up of protein aggregates by other proteins and consequently reduces ROS and, how this might be connected to autophagy. When overexpressed, stefin B forms protein aggregates itself and these protein aggregates induce autophagy. Similarly, cystatin C was shown to bind Aβ and to induce autophagy. It is also suggested how more knowledge about the role of stefin B in a cell’s response to misfolded proteins could be used to modulate progressive myoclonus epilepsy of type 1 EPM1 disease.

Role of herpes simplex virus type 1 (HSV-1) in the pathogenesis of peptic ulcer disease

2001 ◽  
Vol 120 (5) ◽  
pp. A136-A137
Author(s):  
K TSAMAKIDES ◽  
E PANOTOPOULOU ◽  
D DIMITROULOPOULOS ◽  
M CHRISTOPOULO ◽  
D XINOPOULOS ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Peptic Ulcer Disease ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Ulcer Disease ◽  
Simplex Virus

The role of stress and coping in the management of type 1 diabetes mellitus among college students

2013 ◽  
Author(s):  
Jenifer Thomas ◽  
John Moring ◽  
Anne Bowen ◽  
Adara Lindt ◽  
Victoria Emerson
Keyword(s):  
Diabetes Mellitus ◽  
College Students ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Stress And Coping ◽  
And Coping

The Role of Secrecy and Disclosure in Type 1 Diabetes Adherence and Glycemic Control

2013 ◽  
Author(s):  
P. Osborn ◽  
C. A. Berg ◽  
A. E. Hughes ◽  
P. Pham ◽  
D. J. Wiebe
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Control

Dissecting the role of Corticotropin-releasing hormone receptor type 1 in Alzheimer's Disease

2011 ◽  
Vol 44 (06) ◽  
Author(s):  
K Lerche ◽  
M Willem ◽  
K Kleinknecht ◽  
C Romberg ◽  
U Konietzko ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Hormone Receptor ◽  
Receptor Type ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

The role of hepatic 11[b]-hydroxysteroid dehydrogenase type 1 in cholesterol homeostasis

2013 ◽  
pp. 1-1
Author(s):  
Kajal Manwani ◽  
Tak Y Man ◽  
Christopher J Kenyon ◽  
Ruth Andrew ◽  
Karen E Chapman ◽  
...  
Keyword(s):  
Hydroxysteroid Dehydrogenase ◽  
Cholesterol Homeostasis

Investigating the Role of CD137 Ligand in the Pathogenesis of Type 1 Diabetes

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 317-OR
Author(s):  
BARDEES FODA ◽  
MATTHEW H. FORSBERG ◽  
ASHLEY E. CIECKO ◽  
KEVIN W. MUELLER ◽  
ARON GEURTS ◽  
...  
Keyword(s):  
Type 1 Diabetes

GENETIC ROLE OF HLA-G14 BASE PAIR INDEL POLYMORPHIC GENE WITH TYPE 1 DIABETIC PATIENTS

2019 ◽  
Vol 22 (09) ◽  
pp. 154-160
Author(s):  
Hasanain Khaleel Shareef ◽  
Ahmed Adil Ali ◽  
Rafah F. Al-Jebori
Keyword(s):  
Base Pair ◽  
Diabetic Patients ◽  
Polymorphic Gene ◽  
Type 1 Diabetic Patients
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