Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model

2019 ◽  
Vol 86 (12) ◽  
pp. 1951-1962 ◽  
Author(s):  
Malsawmhriatzuala Jeremy ◽  
Guruswami Gurusubramanian ◽  
Vikas Kumar Roy
2014 ◽  
Vol 14 (11) ◽  
pp. 975-984 ◽  
Author(s):  
Bruno Cruz Padua ◽  
Joamyr Rossoni Junior ◽  
Cíntia de Brito Magalhaes ◽  
Janaina Seiberf ◽  
Carolina Araujo ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2184
Author(s):  
Soo Im Chung ◽  
Tae-ho Ham ◽  
Mi Young Kang

Women experience physical, mental, and social changes during menopause. It is important to maintain a healthy diet for effective menopause management. The effect of germinated Superjami, a deep violet colored rice cultivar, on the body weight, glucose level, antioxidant defense system, and bone metabolism in a menopausal rat model was investigated. The animals were randomly divided into three groups and fed with a normal diet (ND), a control diet supplemented with 20% (w/w) non-germinated Superjami flour (NGSF), or germinated Superjami flour (GSF) for eight weeks. The NGSF and GSF groups exhibited significantly lower body weight and fat, glucose and insulin contents, adipokine concentrations, and bone resorption biomarker levels, and higher antioxidant enzyme activities and 17-β-estradiol content than the ND group (p < 0.05). The GSF group showed greater glucose homeostasis, antioxidative, and bone metabolism-improving effects compared with the NGSF group. These findings demonstrate that germination could further improve the health-promoting properties of Superjami and that this germinated pigmented rice cultivar could be useful in the treatment and management of menopause-induced hyperglycemia, oxidative stress, and bone turnover imbalance.


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