The Impact of Proximal Roux‐en‐Y Gastric Bypass Surgery on Acetaminophen Absorption and Metabolism

2020 ◽  
Vol 40 (3) ◽  
pp. 191-203
Author(s):  
Kuan‐Fu Chen ◽  
Lingtak‐Neander Chan ◽  
Taurence D. Senn ◽  
Brant K. Oelschlager ◽  
David R. Flum ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
The Impact

The Impact of Gastric Bypass Surgery Compared to Total Knee Arthroplasty on Knee Symptoms

2018 ◽  
Vol 04 (02) ◽  
Author(s):  
Hafiz Kassam ◽  
Allan Okrainec ◽  
Timothy Jackson ◽  
Michael G Zyweil ◽  
Anthony V Perruccio ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Gastric Bypass ◽  
Knee Arthroplasty ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Total Knee ◽  
The Impact

The Impact of a Clinical Pathway for Gastric Bypass Surgery on Resource Utilization

2001 ◽  
Vol 98 (2) ◽  
pp. 97-101 ◽  
Author(s):  
Robert N. Cooney ◽  
Patrick Bryant ◽  
Randy Haluck ◽  
Michelle Rodgers ◽  
Melanie Lowery
Keyword(s):  
Gastric Bypass ◽  
Resource Utilization ◽  
Clinical Pathway ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
The Impact

scholarly journals The impact of gastric bypass surgery compared to total knee arthroplasty for osteoarthritis on knee symptoms

2014 ◽  
Vol 22 ◽  
pp. S405
Author(s):  
M.G. Zywiel ◽  
A. Okrainec ◽  
T. Penner ◽  
H. Kassam ◽  
A. Perruccio ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Gastric Bypass ◽  
Knee Arthroplasty ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Total Knee ◽  
The Impact

scholarly journals Improvements in diabetic albuminuria and podocyte differentiation following Roux-en-Y gastric bypass surgery

2019 ◽  
Vol 17 (1) ◽  
pp. 147916411987903 ◽  
Author(s):  
Aoife L Canney ◽  
Ricardo V Cohen ◽  
Jessie A Elliott ◽  
Cristina M Aboud ◽  
William P Martin ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Gastric Bypass ◽  
High Risk ◽  
Kidney Disease ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Zucker Diabetic Fatty Rats ◽  
Kidney Disease Progression ◽  
Foot Process ◽  
The Impact

Background: Multiple studies demonstrate an albuminuria-lowering impact of Roux-en-Y gastric bypass surgery, but neither evaluation of its penetrance across different baseline levels of albuminuria nor its association with alterations in podocyte phenotype has previously been reported. Methods: We profiled changes in body weight, glycaemic control and urinary albumin excretion following Roux-en-Y gastric bypass surgery in 105 patients with type 2 diabetes, albuminuria of varying degrees of severity and classified as being at moderate or high risk of chronic kidney disease progression according to the Kidney Disease: Improving Global Outcomes 2012 criteria. In parallel pre-clinical studies, the impact of Roux-en-Y gastric bypass surgery on markers of podocyte injury was assessed in the Zucker diabetic fatty rat model of diabetic kidney disease. Results: At 12- to 18-month post-operative follow-up in patients at moderate or high risk of chronic kidney disease, significant reductions in albuminuria were observed across all tertiles of baseline albumin–creatinine ratio, with remission of albuminuria occurring in 78% of patients. Relative to sham-operated control animals, weight loss and improvements in glycaemia following Roux-en-Y gastric bypass surgery in Zucker diabetic fatty rats were paralleled by normalisation of glomerular tuft-size, reductions in podocyte expression of desmin, and preservation of podocyte foot process morphology. Conclusion: Improvements in podocyte differentiation likely underpin the reductions in albuminuria observed following Roux-en-Y gastric bypass surgery.

The impact of gastric bypass surgery on sex hormones and menstrual cycles in premenopausal women

2016 ◽  
Vol 33 (2) ◽  
pp. 160-163 ◽  
Author(s):  
Mette Mandrup Kjær ◽  
Sten Madsbad ◽  
David M. Hougaard ◽  
Arieh S. Cohen ◽  
Lisbeth Nilas
Keyword(s):  
Gastric Bypass ◽  
Sex Hormones ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Premenopausal Women ◽  
Menstrual Cycles ◽  
The Impact

scholarly journals Longitudinal assessment of the quality of life of patients after gastric bypass

2020 ◽  
Author(s):  
DEISE SILVA DE MOURA ◽  
LUCIANA DAPIEVE PATIAS ◽  
NATHALY MARIN HERNANDEZ ◽  
RAQUEL PIPPI ANTONIAZZI ◽  
GLAUCO DA COSTA ALVAREZ ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Bariatric Surgery ◽  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Sf 36 ◽  
Wide Range ◽  
The Impact

Abstract Background Bariatric surgery is currently considered an effective way to lose weight after failure in the clinical treatment over a 2-year period. Severe obesity is associated with a wide range of serious health complications and reduced health-related quality of life and throughout its context has a significant impact on the health, longevity and quality of life of individuals. The objective of this study was to monitor the impact of weight reduction, induced by bariatric gastric bypass surgery, on the quality of life of pre and post-operative patients at 1, 2 and 6 months. Methods Longitudinal observational study conducted from December 2016 to October 2017 in southern Brazil. The convenience sample consisted of 104 obese individuals eligible to undergo bariatric gastric bypass surgery. The quality of life evaluation was performed using the SF-36 self-administered questionnaire (The Medical Outcomes Study Short Form Health Survey). Results Obese patients presented significant weight loss after surgery and in the evaluation of quality of life the mean scores of the 8 domains of the SF-36 obtained a significant improvement (p <0.001) between time 0 and 6, as well as the components of mental health (vitality, social aspects, emotional aspects and mental health) and physical health component (functional capacity, physical aspects, pain and general state of health). Conclusions Patients who underwent gastric bypass bariatric surgery had significant improvements in quality of life during the 6 postoperative months.

scholarly journals Microbial Adaptation Due to Gastric Bypass Surgery: The Nutritional Impact

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1199 ◽  
Author(s):  
Silke Crommen ◽  
Alma Mattes ◽  
Marie-Christine Simon
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Gastric Bypass ◽  
Gut Microbiota ◽  
Intestinal Microbiota ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Liver Fat ◽  
Microbial Composition ◽  
The Impact

Bariatric surgery leads to sustained weight loss and the resolution of obesity-related comorbidities. Recent studies have suggested that changes in gut microbiota are associated with the weight loss induced by bariatric surgery. Several studies have observed major changes in the microbial composition following gastric bypass surgery. However, there are inconsistencies between the reported alterations in microbial compositions in different studies. Furthermore, it is well established that diet is an important factor shaping the composition and function of intestinal microbiota. However, most studies on gastric bypass have not assessed the impact of dietary intake on the microbiome composition in general, let alone the impact of restrictive diets prior to bariatric surgery, which are recommended for reducing liver fat content and size. Thus, the relative impact of bariatric surgery on weight loss and gut microbiota remains unclear. Therefore, this review aims to provide a deeper understanding of the current knowledge of the changes in intestinal microbiota induced by bariatric surgery considering pre-surgical nutritional changes.

scholarly journals IMPACT OF ROUX-EN-Y GASTRIC BYPASS SURGERY (RYGB) ON METABOLIC SYNDROME COMPONENTS AND ON THE USE OF ASSOCIATED DRUGS IN OBESE PATIENTS

2017 ◽  
Vol 54 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Vilma Maria JUNGES ◽  
Jarbas Marinho CAVALHEIRO ◽  
Eliana Franzoi FAM ◽  
Vera Elizabeth CLOSS ◽  
João Feliz MORAES ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Lipid Lowering ◽  
Obese Patients ◽  
Historical Cohort ◽  
Prevalence Of Obesity ◽  
The Impact ◽  
Metabolic Syndrome Components

ABSTRACT BACKGROUND The prevalence of obesity and metabolic syndrome is increasing worldwide and both behavior modification and drug therapy have low adherence. Gastric bypass has shown effective results in both reducing weight and improving comorbidities. OBJECTIVE To evaluate the impact of Roux-en-Y Gastric Bypass Surgery (RYGB) on both metabolic syndrome components and the use of associated drugs in obese patients. METHODS Historical cohort of patients subjected to Roux-en-Y Gastric Bypass Surgery (RYGB) between January 2007 and March 2014 in a private clinic. The sample consisted of 273 obese class II and III individuals, 86.4% of whom were female, with age ≥20 years, followed up for 2 months after surgery. Sociodemographic, anthropometric, biochemical, clinical, and drug-use data were collected from patients’ medical records. RESULTS Significant differences were found in weight, body mass index and waist circumference, after 60 postoperative days. Components for metabolic syndrome diagnosis (hypertension P=0.001; hyperglycemia P<0.001; hypertriglyceridemia P=0.006) were reduced after 60 days of postoperative, with the exception HDL-c (P=0.083). There was a significant reduction in the use of antihypertensive (P<0.001), hypoglycemic (P=0.013), lipid lowering (P<0.001), and antiobesity (P=0.010) drugs and increased use of gastroprotective drugs, vitamins, and minerals (P<0.001) after 60 postoperative days. CONCLUSION Patients subjected to Roux-en-Y Gastric Bypass Surgery exhibited both weight loss and significant improvement not only in metabolic syndrome components (except for HDL-c) but in the use of drugs associated with obesity and metabolic syndrome.

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