To the Editor: Re: ?Mucoepidermoid carcinoma of the bronchus presenting with a negative chest X-ray and normal pulmonary function in two teenagers: Two case reports and review of the literature? by Robert J. Giusti and Raja M. Flores (Pediatric Pulmonology 2004;37:81-84)

AbstractForeign body aspiration is a very common problem in children and toddlers and still a serious and sometimes fatal condition. We are reporting on a 2-year-old white asthmatic male who choked on a chick pea and presented with subcutaneous emphysema, and on chest X-ray with an isolated pneumomediastinum but not pneumothorax. On review of the literature an isolated pneumomediastinum without pneumothorax was rarely reported. This presented a challenge in management mainly because of the technique that we had to use in order to undergo bronchoscopy and removal of the foreign body. Apnoeic diffusion oxygenation was used initially while the foreign body was removed piecemeal, and afterwards intermittent positive pressure ventilation was used. The child did very well, and his subcutaneous emphysema and pneumomediastinum remarkably improved immediately post surgery.

Download Full-text

Relationship between Chest X-ray Findings and Pulmonary Function Tests in Dust Workers

Industrial Health ◽

10.2486/indhealth.43.256 ◽

2005 ◽

Vol 43 (1) ◽

pp. 256-266 ◽

Cited By ~ 3

Author(s):

Yoko TONORI ◽

Masato NIITSUYA ◽

Toshihiko SATO ◽

Yumiko SUGIURA ◽

Hitoshi MIYAKE ◽

...

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Tests ◽

X Ray ◽

Function Tests ◽

Chest X Ray

Download Full-text

Absence of major fibrotic adverse events in hyperprolactinemic patients treated with cabergoline

Acta Endocrinologica ◽

10.1530/eje-09-0989 ◽

2010 ◽

Vol 162 (4) ◽

pp. 667-675 ◽

Cited By ~ 28

Author(s):

M Lafeber ◽

A M E Stades ◽

G D Valk ◽

M J Cramer ◽

F Teding van Berkhout ◽

...

Keyword(s):

Adverse Events ◽

Pulmonary Function ◽

Pulmonary Function Test ◽

Adverse Reactions ◽

Valvular Regurgitation ◽

X Ray ◽

Increased Risk ◽

Function Test ◽

Additional Imaging ◽

Chest X Ray

BackgroundCabergoline, a dopamine agonist used to treat hyperprolactinemia, is associated with an increased risk of fibrotic adverse reactions, e.g. cardiac valvular fibrosis, pleuropulmonary, and retroperitoneal fibrosis.ObjectiveThis study evaluated the prevalence and risk of fibrotic adverse reactions during cabergoline therapy in hyperprolactinemic and acromegalic patients.DesignA cross-sectional study was conducted in a University Hospital.PatientsA total of 119 patients with hyperprolactinemia and acromegaly who were on cabergoline therapy participated in the study.MethodsAll patients were requested to undergo a cardiac assessment, pulmonary function test, chest X-ray, and blood tests as recommended by the European Medicine Agency. Matched controls were recruited to compare the prevalence of valvular regurgitation. Cardiac valvular fibrosis was evaluated by assessing valvular regurgitation and the mitral valve tenting area (MVTa). The risk of pleuropulmonary fibrosis was assessed by a pulmonary function test, a chest X-ray, and if indicated, by additional imaging studies.ResultsThe prevalence of clinically relevant valvular regurgitation was not significantly different between cases (11.3%) and controls (6.1%; P=0.16). The mean MVTa was 1.27±0.17 and 1.24±0.21 cm2 respectively (P=0.54). Both valvular regurgitation and the MVTa were not related to the cumulative dose of cabergoline. A significantly decreased pulmonary function required additional imaging in seven patients. In one patient, possible early interstitial fibrotic changes were seen. Lung function impairment was not related to the cumulative cabergoline dose.ConclusionCabergoline, typically dosed for the long-term treatment of hyperprolactinemia or acromegaly, appears not to be associated with an increased risk of fibrotic adverse events.

Download Full-text

A cohort study using pulmonary function tests and x-ray examination in toner-handling workers

Human & Experimental Toxicology ◽

10.1177/0960327113520018 ◽

2014 ◽

Vol 34 (4) ◽

pp. 345-356 ◽

Cited By ~ 4

Author(s):

H Kitamura ◽

N Terunuma ◽

S Kurosaki ◽

K Hata ◽

M Masuda ◽

...

Keyword(s):

Pulmonary Function ◽

Health Effects ◽

Pulmonary Function Tests ◽

Personal Exposure ◽

Working Environment ◽

X Rays ◽

Cross Sectional ◽

X Ray ◽

Function Tests ◽

Chest X Ray

Objectives: This study uses pulmonary function tests and chest x-ray examinations to examine the relationship between toner-handling work and its health effects. Methods: The subjects were 1504 male workers in a Japanese toner and photocopier manufacturing company, in the age range from 19 to 50 years in 2003. Personal exposure measurements, pulmonary function tests, chest x-ray examinations, biomarker measurements, and a questionnaire about respiratory symptoms were conducted. The present study reports the results of pulmonary function tests and chest x-ray examinations conducted in the subjects, which includes a cross-sectional study on the toner handling and non-handling workers and a longitudinal study from 2003 to 2008. Results: Few significant findings were suspected to be caused by toner exposure found in pulmonary function indices in both the cross-sectional and longitudinal studies. Any obvious fibrotic findings in chest x-ray findings related to the toner exposure could not be found out. Conclusion: No evidence of adverse effects on pulmonary function indices and chest x-rays was present in the toner-handling workers as compared to the nonspecifically exposed workers. Although the toner exposure concentration is quite low in the current well-controlled working environment, even among the toner-handling workers, we would like to continue this study in the future to verify the toner exposure health effects.

Download Full-text

Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature

Case Reports in Pulmonology ◽

10.1155/2015/370462 ◽

2015 ◽

Vol 2015 ◽

pp. 1-6

Author(s):

Shadi Rezai ◽

Stephen LoBue ◽

Daniel Adams ◽

Yewande Oladipo ◽

Ramses Posso ◽

...

Keyword(s):

Case Report ◽

Developed Countries ◽

Physiological Changes ◽

Review Of The Literature ◽

X Ray ◽

Delay In Diagnosis ◽

The Past ◽

History Of ◽

Chest X Ray ◽

Patient Refusal

Background.Tuberculosis (TB) is a disease that affects hundreds of millions of people across the world. However, the incidence in developed countries has decreased over the past decades causing physicians to become unfamiliar with its unspecific symptoms. Pregnant individuals are especially difficult because many symptoms of active TB can mimic normal physiological changes of pregnancy. We present a case report of a 26-year-old multiparous woman, G4P3003, at 38-week gestation with a history of positive PPD who emigrated from Ghana 6 years ago. She came to the hospital with an initial complaint of suprapubic pain, pressure, and possible leakage of amniotic fluid for the past week. Patient also complained of a productive cough for the past 3 to 4 months with a decrease in vision occurring with the start of pregnancy. Visual acuity was worse than 20/200 in both eyes. Definitive diagnosis of active TB was delayed due to patient refusal of chest X-ray. Fortunately, delay in diagnosis was minimized since patient delivered within 24 hours of admission. Active TB was confirmed with intraocular dissemination. Patient had optic atrophy OS (left eye) and papillitis, choroiditis, and uveitis OD (right eye) due to TB infiltration. Fetus was asymptomatic and anti-TB therapy was started for both patients.

Download Full-text

Cardiac instability due to Pneumomediastinum during second stage of labour

Scottish Medical Journal ◽

10.1258/rsmsmj.54.2.58h ◽

2009 ◽

Vol 54 (2) ◽

pp. 58-58

Author(s):

J Rafi ◽

H Muppala ◽

B Schaefer

Keyword(s):

Subcutaneous Emphysema ◽

Case Reports ◽

Neck Region ◽

High Dependency Unit ◽

X Ray ◽

Second Stage ◽

Cardiovascular Instability ◽

Second Stage Of Labour ◽

High Dependency ◽

Chest X Ray

This case reports spontaneous pneumomediastinum in the second stage of labour leading to cardiovascular instability. Forceps were used to expedite delivery. Examination revealed characteristic crepitus of subcutaneous emphysema in the neck region, which was confirmed on chest X-Ray and CT scan. The patient was managed in the high dependency unit (HDU) for 48 hours and made a full recovery.

Download Full-text

Lund–Mackay Computed Tomography Score Is Associated With Obstructive Pulmonary Function Changes in Chronic Cough Patients

American Journal of Rhinology and Allergy ◽

10.1177/1945892418825094 ◽

2019 ◽

Vol 33 (3) ◽

pp. 294-301 ◽

Cited By ~ 2

Author(s):

Shin Kariya ◽

Mitsuhiro Okano ◽

Takaya Higaki ◽

Tomoyasu Tachibana ◽

Toru Rikimaru ◽

...

Keyword(s):

Computed Tomography ◽

Lung Function ◽

Pulmonary Function ◽

Paranasal Sinus ◽

Chronic Cough ◽

Eosinophil Count ◽

Upper Airway ◽

Peripheral Blood Eosinophil ◽

X Ray ◽

Chest X Ray

Background A remarkable relationship between upper airway conditions and lung diseases has been reported. At the same time, sinonasal findings in chronic cough patients have not been fully examined. Objective The purpose of this study is to show paranasal sinus findings and lung function in chronic cough patients without asthma and chest X-ray abnormalities. Methods A total of 1412 patients with persistent cough were enrolled in this study. Of these patients, 376 patients were evaluated for further examination, as the patients with asthma and/or chest X-ray abnormality were excluded from the study. Normal control subjects without any chronic respiratory symptoms were also recruited. Pulmonary function was examined by spirometry. A bronchial obstruction reversibility test was applied. The Lund–Mackay computed tomography (CT) score, peripheral blood eosinophil count, and immunoglobulin E concentration in serum samples were examined. The Sino-Nasal Outcome Test was used to determine the severity of clinical symptoms. Results The patients with an abnormal soft tissue shadow in the paranasal sinus had significant obstructive lung function. The percent predicted forced expiratory volume in 1 second (FEV1.0) and the FEV1.0/forced vital capacity ratio negatively correlated with Lund–Mackay CT scores both before and after bronchodilator inhalation. There was a statistically significant correlation between pulmonary function and eosinophil count. Conclusion The patients with chronic cough frequently had paranasal sinus abnormalities. The Lund–Mackay CT score may be useful for assessing the condition of the lower airway in chronic cough patients. Upper airway examinations should play a part in the management of chronic cough.

Download Full-text

Chronic Disseminated Intravascular Coagulation and Metastatic Brain Tumor: A Case Report and Review of the Literature

Neurosurgery ◽

10.1227/00006123-198305000-00020 ◽

1983 ◽

Vol 12 (5) ◽

pp. 580-584 ◽

Cited By ~ 16

Author(s):

Raymond Sawaya ◽

Jerome A. Donlon

Keyword(s):

Disseminated Intravascular Coagulation ◽

Metastatic Lesion ◽

Review Of The Literature ◽

Current Case ◽

X Ray ◽

Intravascular Coagulation ◽

Primary Lung Carcinoma ◽

Repeat Chest ◽

Chest X Ray ◽

The Brain

Abstract A patient who had a primary lung carcinoma in remission but had a solitary metastatic lesion to the cerebellum was referred to the neurosurgery service. He was noted to be thrombocytopenic, and further hemostatic evaluation revealed chronic disseminated intravascular coagulation. He was treated with heparin and platelet transfusions. Although the fibrinogen levels improved, the thrombocytopenia persisted. Four weeks after admission, repeat chest x-ray films and tomograms indicated progressing metastatic nodules. A review of the literature reveals a variety of hemostatic defects associated with tumor metastatic to the brain. This current case indicates the need for careful hemostatic evaluation in all patients with brain lesions.

Download Full-text