Short-term control of capsaicin on blood and oxidative stress of ratsin vivo

2003 ◽  
Vol 17 (5) ◽  
pp. 454-458 ◽  
Author(s):  
Chung-Yung Jetty Lee ◽  
Minsun Kim ◽  
Sung-Won Yoon ◽  
Cherl-Ho Lee
2006 ◽  
Vol 25 (5) ◽  
pp. 1337 ◽  
Author(s):  
Juliana Zomer Sandrini ◽  
Francesco Regoli ◽  
Daniele Fattorini ◽  
Alessandra Notti ◽  
Alan Ferreira Inácio ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Michał Dobrakowski ◽  
Marta Boroń ◽  
Ewa Birkner ◽  
Aleksandra Kasperczyk ◽  
Ewa Chwalińska ◽  
...  

The present study was designed to explore the possible influence of subacute exposure to lead on the levels of selected essential metals, selected proteins related to them, and oxidative stress parameters in occupationally exposed workers. The study population included 36 males occupationally exposed to lead for 36 to 44 days. Their blood lead level at the beginning of the study was 10.7 ± 7.67 μg/dl and increased to the level of 49.1 ± 14.1 μg/dl at the end of the study. The levels of calcium, magnesium, and zinc increased significantly after lead exposure compared to baseline by 3%, 3%, and 8%, respectively, while the level of copper decreased significantly by 7%. The malondialdehyde (MDA) level and the activities of catalase (CAT) and superoxide dismutase (SOD) did not change due to lead exposure. However, the level of lipid hydroperoxides (LPH) in serum increased significantly by 46%, while the level of erythrocyte lipofuscin (LPS) decreased by 13%. The serum levels of essential metals are modified by a short-term exposure to lead in occupationally exposed workers. A short-term exposure to lead induces oxidative stress associated with elevated levels of LPH but not MDA.


2009 ◽  
Vol 15 (7) ◽  
pp. S166
Author(s):  
Miho Kitamura ◽  
Miyuki Kobara ◽  
Akiko Furumori ◽  
Kazuki Noda ◽  
Tatsuya Shiraishi ◽  
...  

2014 ◽  
Vol 52 (2) ◽  
pp. 249-256 ◽  
Author(s):  
Eliezer Joseph Tassone ◽  
Maria Perticone ◽  
Angela Sciacqua ◽  
Simona Fortunata Mafrici ◽  
Chiara Settino ◽  
...  

2019 ◽  
Vol 25 (4) ◽  
pp. 256-269
Author(s):  
Yeganeh Feizi ◽  
◽  
Mohammad Esmaeil Afzalpur ◽  
Seyed-Hosein Abtahi-Eivary ◽  
◽  
...  

Aims Physical activity is usually accompanied by free radicals’ production and oxidative stress. Moreover, to prevent adverse effects, coaches and athletes have to use proper supplementation. Therefore, the present study aimed to investigate the effect of short-term coenzyme Q10 supplementation on malondialdehyde and serum catalase enzyme activity following moderate and severe acute resistance training in inactive female students. Methods & Materials In total, 27 female students were randomly divided into three groups; the groups were homogeneous and equal (two groups of resistance training and one control group). The experimental groups were subjected to moderate-intensity acute (70% 1RM) acute and severe acute activity (85% 1RM) and supplemented with coenzyme Q10 (30 mg /d). CAT and MDA were measured in ELISA using a human kit. Findings Moderate and severe acute resistance activities did not alter MDA and catalytic activity (P>0.05); however, after 2 weeks of coenzyme Q10 supplementation, those resulted in a significant decrease in MDA (0.006 and 0.01, respectively) and CAT (0.04 and 0.007, respectively). There were no significant differences between the effects of two exercises (P>0.05). Conclusion Short-term (two weeks) supplementation of coenzyme Q10 and severe acute resistance activity could reduce two important oxidative stress indexes (MDA and CAT).


2015 ◽  
Vol 93 (6) ◽  
pp. 2948-2955 ◽  
Author(s):  
Y. L. Huang ◽  
M. S. Ashwell ◽  
R. S. Fry ◽  
K. E Lloyd ◽  
W. L. Flowers ◽  
...  

2006 ◽  
Vol 110 (4) ◽  
pp. 483-489 ◽  
Author(s):  
Michel White ◽  
Anique Ducharme ◽  
Reda Ibrahim ◽  
Lucette Whittom ◽  
Joel Lavoie ◽  
...  

In the present study, we evaluated circulating pro-inflammatory mediators and markers of oxidative stress in patients with decompensated CHF (congestive heart failure) and assessed whether clinical recompensation by short-term inotropic therapy influences these parameters. Patients with worsening CHF (n=29, aged 61.9±2.7 years), NYHA (New York Heart Association) class III–IV, and left ventricular ejection fraction of 23.7±1.8% were studied. Controls comprised age-matched healthy volunteers (n=15; 54.1±3.2 years). Plasma levels of cytokines [IL (interleukin)-6 and IL-18], chemokines [MCP-1 (monocyte chemotactic protein-1)], adhesion molecules [sICAM (soluble intercellular adhesion molecule), sE-selectin (soluble E-selectin)], systemic markers of oxidation [TBARS (thiobarbituric acid-reactive substances), 8-isoprostaglandin F2α and nitrotyrosine] and hs-CRP (high-sensitivity C-reactive protein) were measured by ELISA and colorimetric assays at admission and 30 days following 72-h milrinone (n=15) or dobutamine (n=14) infusion. Plasma IL-6, IL-18, sICAM, E-selectin, hs-CRP and oxidative markers were significantly higher in patients on admission before inotropic treatment compared with controls (P<0.05). Short-term inotropic support improved clinical status as assessed by NYHA classification and by the 6-min walk test and significantly decreased plasma levels of IL-6, IL-18, sICAM, hs-CRP and markers of oxidation (P<0.05) at 30 days. The effects of milrinone and dobutamine were similar. In conclusion, our results demonstrate that patients with decompensated CHF have marked systemic inflammation and increased production of oxygen free radicals. Short-term inotropic support improves functional status and reduces indices of inflammation and oxidative stress in patients with decompensated CHF.


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