Novel Carboxylic Acid Functionalized Dendronized Polymer: A Homogeneous, Reusable Metal Free Acid Catalyst for the Synthesis of Symmetric and Unsymmetric Xanthene Derivatives

2021 ◽  
Vol 6 (48) ◽  
pp. 13832-13841
Author(s):  
Kottayil Hiba ◽  
Machingal Shaibuna ◽  
Sreedharan Prathapan ◽  
Krishnapillai Sreekumar
Keyword(s):  
Carboxylic Acid ◽  
Free Acid ◽  
Acid Catalyst ◽  
Metal Free ◽  
Xanthene Derivatives ◽  
Dendronized Polymer

Role of graphene oxide as a heterogeneous acid catalyst and benign oxidant for synthesis of benzimidazoles and benzothiazoles

RSC Advances ◽  
2016 ◽  
Vol 6 (10) ◽  
pp. 8164-8172 ◽  
Author(s):  
Kiran B. Dhopte ◽  
Rahul S. Zambare ◽  
Anand V. Patwardhan ◽  
Parag R. Nemade
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Free Acid ◽  
Acid Catalyst ◽  
Dual Role ◽  
Metal Free ◽  
Active Metal ◽  
Reduced Graphene ◽  
Heterogeneous Acid Catalyst

Graphene oxide plays a dual role as active metal-free acid catalyst and as non-toxic oxidant for benzothiazole and benzimidazole synthesis. Isolated partially reduced graphene oxide was re-oxidized to regenerate the catalyst and restore its activity.

A metal-free radical cascade reaction of phosphine oxides with 2-aryloxy phenylacetylenes to assemble diphosphonyl xanthene derivatives

2021 ◽  
Author(s):  
Tao Fan ◽  
Yan Liu ◽  
Caina Jiang ◽  
Yanli Xu ◽  
Yan-Yan Chen
Keyword(s):  
Free Radical ◽  
Transition Metal ◽  
Cascade Reaction ◽  
Phosphine Oxides ◽  
Metal Free ◽  
Mild Conditions ◽  
Xanthene Derivatives ◽  
Reaction Proceeds ◽  
Radical Cascade

A radical cascade reaction of 2-aryloxy phenylacetylene with phosphine oxides promoted by K2S2O8 was developed, provided diphosphonyl xanthenes as products. This reaction proceeds under transition metal-free and mild conditions with...

scholarly journals Immobilization of Lewis acidic ionic liquid on perlite nanoparticle surfaces as a highly efficient solid acid catalyst for the solvent-free synthesis of xanthene derivatives

RSC Advances ◽  
2019 ◽  
Vol 9 (35) ◽  
pp. 19940-19948 ◽  
Author(s):  
L. Moradi ◽  
M. Mirzaei
Keyword(s):  
Ionic Liquid ◽  
Solid Acid Catalyst ◽  
Acid Catalyst ◽  
Solvent Free ◽  
High Yield ◽  
Efficient Catalyst ◽  
Acidic Ionic Liquid ◽  
Highly Efficient ◽  
Xanthene Derivatives ◽  
Lewis Acidic Ionic Liquid

Perlite nanoparticles were prepared, modified with Lewis acidic ionic liquid, and used as a highly efficient catalyst for the eco-friendly, solvent free and high yield synthesis of xanthenesviaa multicomponent reaction.

Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal-Free CO Releasing Molecule Activated by Green Light

2013 ◽  
Vol 15 (17) ◽  
pp. 4552-4555 ◽  
Author(s):  
Lovely Angel Panamparambil Antony ◽  
Tomáš Slanina ◽  
Peter Šebej ◽  
Tomáš Šolomek ◽  
Petr Klán
Keyword(s):  
Carboxylic Acid ◽  
Transition Metal ◽  
Green Light ◽  
Metal Free

Synthesis and singlet oxygen production of azaphthalocyanines bearing functional derivatives of carboxylic acid

2006 ◽  
Vol 10 (02) ◽  
pp. 122-131 ◽  
Author(s):  
Zbynek Musil ◽  
Petr Zimcik ◽  
Miroslav Miletin ◽  
Kamil Kopecky ◽  
Marek Link ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Singlet Oxygen ◽  
Hexanoic Acid ◽  
Oxygen Production ◽  
Metal Free ◽  
Dye Sensitized ◽  
Structure Activity ◽  
Functional Derivatives ◽  
Derivatives Of ◽  
Free Magnesium

New metal-free, magnesium and zinc azaphthalocyanines ( AzaPc ) were prepared from 6-(3-tert-butylsulfany1-5,6-dicyanopyrazine-2-ylamino)hexanoic acid and its butylester and N,N-diethylamide. Their singlet oxygen production was measured by a dye-sensitized photooxidation of 1,3-diphenylisobenzofuran ( DPBF ) and ΦΔ values were calculated. It was found that the presence of carboxylic acid in the structure of AzaPc decreases their singlet oxygen production. Singlet oxygen activity of the newly prepared compounds (containing mixed alkylamino and alkylsulfanyl peripheral substituents) lies between purely alkylsulfanyl and alkylamino derivatives of AzaPc . This fact further supports previously proposed structure-activity relationships, where alkylsulfanyl derivatives belong to the best singlet oxygen producers while the presence of alkylamino substituents in the structure rapidly decreases their photodynamic properties.

scholarly journals 1,3-Dioxolan-4-Ones as Promising Monomers for Aliphatic Polyesters: Metal-Free, in Bulk Preparation of PLA

Polymers ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2396
Author(s):  
Stefano Gazzotti ◽  
Marco Aldo Ortenzi ◽  
Hermes Farina ◽  
Alessandra Silvani
Keyword(s):  
Molecular Weight ◽  
Thermal Properties ◽  
Acid Catalyst ◽  
Monomer Conversion ◽  
Reaction Conditions ◽  
Aliphatic Polyesters ◽  
Metal Free ◽  
Weight Growth ◽  
Double Activation

The first example of solvent-free, organocatalyzed, polymerization of 1,3-dioxolan-4-ones, used as easily accessible monomers for the synthesis of polylactic acid (PLA), is described here. An optimization of reaction conditions was carried out, with p-toluensulfonic acid emerging as the most efficient Brønsted acid catalyst. The reactivity of the monomers in the tested conditions was studied following the monomer conversion by 1H NMR and the molecular weight growth by SEC analysis. A double activation polymerization mechanism was proposed, pointing out the key role of the acid catalyst. The formation of acetal bridges was demonstrated, to different extents depending on the nature of the aldehyde or ketone employed for lactic acid protection. The polymer shows complete retention of stereochemistry, as well as good thermal properties and good polydispersity, albeit modest molecular weight.

A practical metal-free homolytic aromatic alkylation protocol for the synthesis of 3-(pyrazin-2-yl)bicyclo[1.1.1]pentane-1-carboxylic acid

2016 ◽  
Vol 14 (40) ◽  
pp. 9485-9489 ◽  
Author(s):  
Navanita T. Thirumoorthi ◽  
Vikrant A. Adsool
Keyword(s):  
Carboxylic Acid ◽  
Building Block ◽  
Medicinal Chemistry ◽  
Biological Study ◽  
Metal Free

As a part of our ongoing synthetic quest to expand the frontiers of contemporary medicinal chemistry, we now report an expedient synthesis of a potentially useful bicyclo[1.1.1]pentane building block, 3-(pyrazin-2-yl)bicyclo[1.1.1]pentane-1-carboxylic acid. This report also showcases the application of this motif as a “spacer” probe in a biological study.

Metal-free intramolecular amino-acyloxylation of 2-aminostyrene with carboxylic acid for the synthesis of 3-acyloxyl indolines in water

2017 ◽  
Vol 19 (9) ◽  
pp. 2076-2079 ◽  
Author(s):  
Liyan Liu ◽  
Zhiyong Wang
Keyword(s):  
Carboxylic Acid ◽  
Free Amino ◽  
Metal Free

A metal-free amino-acyloxylation of 2-aminostyrene was developed for the synthesis of 3-acyloxyl indolines.

Sign in / Sign up

Export Citation Format

Share Document