Polyamine‐Responsive Morphological Transformation of a Supramolecular Peptide for Specific Drug Accumulation and Retention in Cancer Cells

Small ◽  
2021 ◽  
pp. 2101139
Author(s):  
Chen Sun ◽  
Ziyi Wang ◽  
Kuikun Yang ◽  
Ludan Yue ◽  
Qian Cheng ◽  
...  
Nano Letters ◽  
2018 ◽  
Vol 18 (8) ◽  
pp. 4641-4646 ◽  
Author(s):  
Francesco Canfarotta ◽  
Larissa Lezina ◽  
António Guerreiro ◽  
Joanna Czulak ◽  
Alexey Petukhov ◽  
...  

1992 ◽  
Vol 50 (5) ◽  
pp. 677-682 ◽  
Author(s):  
Marie-ThéRéSe Dimanche-Boitrel ◽  
Hélène Pelletier ◽  
Philippe Genne ◽  
Jean-Michel Petit ◽  
Christian Le Grimellec ◽  
...  

2009 ◽  
Vol 29 (5) ◽  
pp. 1697-1701 ◽  
Author(s):  
Renyun Zhang ◽  
Chunhui Wu ◽  
Xuemei Wang ◽  
Qian Sun ◽  
Baoan Chen ◽  
...  

2013 ◽  
Vol 834-836 ◽  
pp. 573-576
Author(s):  
Jing Jing Ouyang ◽  
Yu Qiang Wang ◽  
Wen Tang

Ganoderic acid R (GA-R) possessed significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1). The results indicated that the inhibition effect of the GA-R was due to the induction of apoptosis. The use of GA-R in vitro resulted in a restoration response of the KB-A-1/Dox cells to the anti-tumor drug doxorubicin by stimulating the drug accumulation within the cells. The index of MDR reversion of GA-R was about 22 folds. The findings show that the ganoderma triterpene may be good candidates for anti-tumor and anti MDR chemotherapy.


2015 ◽  
Vol 12 (7) ◽  
pp. 2237-2244 ◽  
Author(s):  
Fei Chen ◽  
Yuanyuan Zhao ◽  
Yuanming Pan ◽  
Xiangdong Xue ◽  
Xu Zhang ◽  
...  

2016 ◽  
Vol 8 (45) ◽  
pp. 30722-30734 ◽  
Author(s):  
Wen-Ying Huang ◽  
Jia-Ni Lin ◽  
Jer-Tsong Hsieh ◽  
Shen-Chieh Chou ◽  
Chih-Ho Lai ◽  
...  

2006 ◽  
Vol 16 (18) ◽  
pp. 4808-4812 ◽  
Author(s):  
Jingyuan Li ◽  
Chunhui Wu ◽  
Feng Gao ◽  
Renyun Zhang ◽  
Gang Lv ◽  
...  

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