The relationship of gestational age to vitamin A induced postnatal dysfunction,

BackgroundThere is no consensus on the effects that low birth weight, premature birth and intrauterine growth have on later depression.AimsTo review systematically the evidence on the relationship of low birth weight, smallness for gestational age (SGA) and premature birth with adult depression.MethodWe searched the literature for original studies assessing the effect of low birth weight, premature birth and SGA on adult depression. Separate meta-analyses were carried out for each exposure using random and fixed effects models. We evaluated the contribution of methodological covariates to heterogeneity using meta-regression.ResultsWe identified 14 studies evaluating low birth weight, 9 premature birth and 4 SGA. Low birth weight increased the odds of depression (OR = 1.39, 95% CI 1.21–1.60). Premature birth and SGA were not associated with depression, but publication bias might have underestimated the effect of the former and only four studies evaluated SGA.ConclusionsLow birth weight was associated with depression. Future studies evaluating premature birth and SGA are needed.

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A Sonographic Study on Estimating of Gestational Age by Placental Thickness

Asian Journal of Medical Radiological Research ◽

10.47009/ajmrr.2020.8.1.20 ◽

2020 ◽

Vol 8 (1) ◽

pp. 110-113

Author(s):

Prashanth G Patil ◽

KM Nataraj ◽

Shaik Hussain Saheb

Keyword(s):

Correlation Coefficient ◽

Gestational Age ◽

Ultrasound Examination ◽

Prediction Interval ◽

Good Alternative ◽

Third Trimester ◽

Biometric Parameters ◽

Relationship Of ◽

The Relationship ◽

Placental Thickness

Background: Knowledge of gestational age (GA) is important because it affects clinical management in many ways. Ultrasonography has provided a safe and noninvasive means of dating a pregnancy. The purpose of the present study is to assess the relationship of placental thickness with gestational age and to compare it with other sonographic parameters used to estimate gestational age. Subjects and Methods: The study included 242 normal pregnant women who knew their last menstrual period (LMP). After taking consent, all the women underwent an ultrasound examination. During the scan, besides measuring routine biometric parameters, Placental thickness at the cord insertion was also measured. A retrospective study was designated to test the hypothesis that placental thickness in an age dependant variable and hence can predict gestational age. In the end, the predicted gestational age by placental thickness was compared with gestational age as determined by other sonographic parameters. Results: Placental thickness showed a linear progression in relation to the menstrual age. The correlation coefficient was found to be 0.86(p<0.001). The regression equation was formulated by regressing gestational age on the measured placental thickness. The correlation coefficient between GA-LMP and GA-USG was 0.92 as compared to 0.86 between GA-LMP and GA-PT. The standard error for other USG parameters was +2.32 compared to +2.96 for placental thickness. Conclusion: Placental thickness being a fusion of menstrual age, can be used to predict the gestational age by using the regression formula. Gestational age calculated by other USG parameters is closer to menstrual age as compared to that by placental thickness. The prediction interval was slightly more when the placental thickness was used instead of other USG parameters. Placental thickness is a good alternative parameter for predicting gestational age in the second and third trimester.

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The Relationship of Birth Weight, Feeding and Gestational Age with Serum Copper and Zinc in Premature Neonates

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2019/40236.12846 ◽

2019 ◽

Author(s):

Omid Reza Zekavat ◽

Alireza Sahraian ◽

Somayeh Esmaili ◽

Sezaneh Haghpanah ◽

Susan Rabie ◽

...

Keyword(s):

Birth Weight ◽

Gestational Age ◽

Serum Copper ◽

Premature Neonates ◽

Copper And Zinc ◽

Relationship Of ◽

The Relationship

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Reduced Growth in Non-Small for Gestational Age Fetuses from 35 Weeks of Gestation to Birth and Perinatal Outcomes

Fetal Diagnosis and Therapy ◽

10.1159/000519639 ◽

2021 ◽

pp. 1-10

Author(s):

Peña Dieste Pérez ◽

Luis M. Esteban ◽

Ricardo Savirón-Cornudella ◽

Faustino R. Pérez-López ◽

Sergio Castán-Mateo ◽

...

Keyword(s):

Gestational Age ◽

Small For Gestational Age ◽

Perinatal Outcomes ◽

Entire Study ◽

Birth Weight Percentile ◽

Gestational Age At Delivery ◽

Study Population ◽

The Difference ◽

Relationship Of ◽

The Relationship

Objective: This study aimed to assess reduced fetal growth between 35 weeks of gestation and birth in non-small for gestational age fetuses associated with adverse perinatal outcomes (APOs). Material and Method: It is a retrospective cohort study of 9,164 non-small for gestational age fetuses estimated by ultrasound at 35 weeks. The difference between the birth weight percentile and the estimated percentile weight (EPW) at 35 weeks of gestation was calculated, and we studied the relationship of this difference with the appearance of APO. APOs were defined as cesarean or instrumental delivery rates for nonreassuring fetal status, 5-min Apgar score <7, arterial cord blood pH <7.10, and stillbirth. Fetuses that exhibited a percentile decrease between both moments were classified into 6 categories according to the amount of percentile decrease (0.01–10.0, 10.01–20.0, 20.01–30.0, 30.01–40.0, 40.01–50.0, and >50.0 percentiles). It was evaluated whether the appearance of APO was related to the amount of this percentile decrease. Relative risk (RR) was calculated in these subgroups to predict APOs in general and for each APO in particular. Receiver operating characteristic and area under curves (AUC) for the difference in the percentile was calculated, used as a continuous parameter in the entire study population. Results: The median gestational age at delivery in uncomplicated pregnancies was 40.0 (39.1–40.7) and in pregnancies with APOs 40.3 (49.4–41.0), p < 0.001. The prevalence of APOs was greater in the group of fetuses with a decrease in percentile (7.6%) compared to those with increased percentile (4.8%) (p < 0.001). The RR was 1.63 (95% CI: 1.365–1.944, p < 0.001). Although the differences were significant in all decreased percentile groups, RRs were significantly higher when decreased growth values were >40 points (RR: 2.036, 95% CI: 1.581–2.623, p < 0.001). The estimated value of the AUC for percentile decrease was 0.58 (0.56–0.61, p < 0.001). Conclusion: Fetuses with a decrease in the EPW between the ultrasound at 35 weeks of gestation and birth have a higher risk of APOs, being double in fetuses with a decrease of >40 percentile points.

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THE RELATIONSHIP OF PLACENTAL THICKNESS WITHGESTATIONALAGE IN THIRD TRIMESTER AND PROBABLE FETAL OUTCOME

10.36106/ijsr/7813794 ◽

2021 ◽

pp. 64-66

Author(s):

Sambhunath Bandyopadhyay ◽

Ritayan Sasmal ◽

Debarshi Jana

Keyword(s):

Birth Weight ◽

Gestational Age ◽

Age Determination ◽

Fetal Outcome ◽

Inclusion Criteria ◽

Third Trimester ◽

Relationship Of ◽

The Relationship ◽

Placental Thickness

Accurate gestational age determination is very important for management of continuation and termination planning of the pregnancy. rd To establish placental thickness as a parameter for determination of gestational age and fetal growth pattern at 3 trimester. 100 primigravida women who are fullling the inclusion criteria and attend gynae &obs OPD or admitted in their third trimester at IPGME&R from January 2017 to june 2018. Placental thickness at 3rd trimester USG scan is moderately correlated with gestational age, if placental thickness expressed in millimeter then it correlated with gestational age at weeks. rd st Placental thickness with >3.2 cm (32 mm) at 3 trimester almost associated with good fetal outcome, with APGAR score >8 at 1 min and birth weight >2500 gm.

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Kisspeptin: new biomarker of pregnancy

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20193105 ◽

2019 ◽

Vol 8 (8) ◽

pp. 3021

Author(s):

Priyanka Meena ◽

Rati Mathur ◽

Mohan L. Meena

Keyword(s):

Pregnant Women ◽

Gestational Age ◽

Positive Relationship ◽

Elisa Method ◽

Medical College ◽

Obstetrics And Gynaecology ◽

Study Participants ◽

Relationship Of ◽

The Relationship ◽

Single Blood Sample

Background: The recently identified hormone kisspeptin has been suggested to play an important regulatory role in placentation. The aim and objective of the study is the measurement of serum kisspeptin level in asymptomatic pregnant women and to find out the association of serum kisspeptin with gestational age in women with early pregnancy.Methods: This was a longitudinal study to the evaluation of 178 asymptomatic pregnant women with a gestation of 6 to 16 weeks attending routine antenatal booking visit recruited as study participants from the Antenatal Clinical of Obstetrics and Gynaecology Department, S.M.S. Medical College and Attached Hospitals, Jaipur, Rajasthan, India.Results: After initial clinical examination of every participant, a single blood sample was taken for the measurement of serum kisspeptin. Serum kisspeptin measurement test was performed by ELISA method and results were expressed as ng/ml. Pregnancy outcome was recorded prospectively. Mean serum kisspeptin level of study participants was 2.80±1.87ng/ml and median were 2.41 (Range 0.244-14.06ng/ml). Our result showed the relationship of serum kisspeptin with gestational age (GA) (p<0.000).Conclusions: serum kisspeptin level increases in pregnancy and showed positive relationship with gestational age significantly (p<0.000).

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Correlation of placental thickness with gestational age in antenatal women

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20193512 ◽

2019 ◽

Vol 8 (8) ◽

pp. 3061

Author(s):

Priyanka Verma ◽

Monika Gupta ◽

Shraddha Verma

Keyword(s):

Interventional Radiology ◽

Gestational Age ◽

Safe Motherhood ◽

Doppler Imaging ◽

Accurate Estimation ◽

Fetal Wellbeing ◽

Relationship Of ◽

The Relationship ◽

Placental Thickness ◽

Period Of Gestation

Background: Accurate estimation of gestational age and fetal wellbeing is mandatory to ensure safe pregnancy and healthy delivery. With recent development in USG, basic scan, Doppler imaging and interventional radiology helped greatly in accurate estimation of gestational age and delivering timely care. The objectives of this study was to determine the USG placental thickness at the level of insertion of cord in antenatal women from gestational age 11 to 40 weeks. To correlate placental thickness with gestational age. To calculate composite gestational age from USG parameters; CRL, BPD, HC, AC, FL. To compare the relationship of menstrual gestational age with placental thickness and composite gestational age separatelyMethods: It is a comparative study of 2 years duration. Total 322 patients were included. Gestational age was determined from LMP. Patient’s routine obstetric USG was done and composite gestational age was calculated from fetal parameters like BPD, HC, AC and FL (CRL in 11 to 14 weeks). At the same time placental thickness was determined at the level of insertion of umbilical cord. The plane of USG image was adjusted so that the thickness measured from cord insertion is perpendicular to the margin of uterine wall.Results: The following parameters were noted: correlation of period of gestation (weeks) with composite gestational age (weeks) correlation of period of gestation (weeks) with gestational age calculated by placental thickness (weeks).Conclusions: Placental thickness can give an estimation of gestational age. The linear correlation and statistical compatibility of placental thickness makes it an alternate parameter for gestational age. Knowledge of correct gestational age helps in delivering proper antenatal care, assessing fetal wellbeing, identifying pathology at the earliest and timely decision of termination and providing safe motherhood.

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