Reduced Growth in Non-Small for Gestational Age Fetuses from 35 Weeks of Gestation to Birth and Perinatal Outcomes

2021 ◽  
pp. 1-10
Author(s):  
Peña Dieste Pérez ◽  
Luis M. Esteban ◽  
Ricardo Savirón-Cornudella ◽  
Faustino R. Pérez-López ◽  
Sergio Castán-Mateo ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Perinatal Outcomes ◽  
Entire Study ◽  
Birth Weight Percentile ◽  
Gestational Age At Delivery ◽  
Study Population ◽  
The Difference ◽  
Relationship Of ◽  
The Relationship

<b><i>Objective:</i></b> This study aimed to assess reduced fetal growth between 35 weeks of gestation and birth in non-small for gestational age fetuses associated with adverse perinatal outcomes (APOs). <b><i>Material and Method:</i></b> It is a retrospective cohort study of 9,164 non-small for gestational age fetuses estimated by ultrasound at 35 weeks. The difference between the birth weight percentile and the estimated percentile weight (EPW) at 35 weeks of gestation was calculated, and we studied the relationship of this difference with the appearance of APO. APOs were defined as cesarean or instrumental delivery rates for nonreassuring fetal status, 5-min Apgar score &#x3c;7, arterial cord blood pH &#x3c;7.10, and stillbirth. Fetuses that exhibited a percentile decrease between both moments were classified into 6 categories according to the amount of percentile decrease (0.01–10.0, 10.01–20.0, 20.01–30.0, 30.01–40.0, 40.01–50.0, and &#x3e;50.0 percentiles). It was evaluated whether the appearance of APO was related to the amount of this percentile decrease. Relative risk (RR) was calculated in these subgroups to predict APOs in general and for each APO in particular. Receiver operating characteristic and area under curves (AUC) for the difference in the percentile was calculated, used as a continuous parameter in the entire study population. <b><i>Results:</i></b> The median gestational age at delivery in uncomplicated pregnancies was 40.0 (39.1–40.7) and in pregnancies with APOs 40.3 (49.4–41.0), <i>p</i> &#x3c; 0.001. The prevalence of APOs was greater in the group of fetuses with a decrease in percentile (7.6%) compared to those with increased percentile (4.8%) (<i>p</i> &#x3c; 0.001). The RR was 1.63 (95% CI: 1.365–1.944, <i>p</i> &#x3c; 0.001). Although the differences were significant in all decreased percentile groups, RRs were significantly higher when decreased growth values were &#x3e;40 points (RR: 2.036, 95% CI: 1.581–2.623, <i>p</i> &#x3c; 0.001). The estimated value of the AUC for percentile decrease was 0.58 (0.56–0.61, <i>p</i> &#x3c; 0.001). <b><i>Conclusion:</i></b> Fetuses with a decrease in the EPW between the ultrasound at 35 weeks of gestation and birth have a higher risk of APOs, being double in fetuses with a decrease of &#x3e;40 percentile points.

scholarly journals Early Physical Linear Growth of Small-for-Gestational-Age Infants Based on Computer Analysis Method

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Li Ruixiang ◽  
Yin Mingrong ◽  
Cui Li ◽  
Zheng Rongxiu
Keyword(s):  
Computer Analysis ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Neonatal Intensive Care ◽  
Linear Growth ◽  
Physical Growth ◽  
Early Group ◽  
Analysis Method ◽  
The Difference ◽  
The Relationship

This article proposes that machine learning can break through the technical limitations of the linear growth test for the early physique of infants smaller than gestational age and can accurately calculate and predict the consequences of the disease. For testing the linear growth of the early physique of infants smaller than gestational age, the data collection and judgment are carried out according to the computer analysis method. Experimental results show that 47.3% of infants younger than gestational age may have suffocation. The experimental subjects designed in this study are small-for-gestational-age infants who were hospitalized in the neonatal intensive care unit from January 2020 to January 2021. According to the relationship between gestational age and birth weight, the survey subjects were divided into two groups: early group and late group. Male and female small-for-gestational-age infants accounted for 68% and 32%, respectively. Among them, the proportion of early gestational age was the most, with more boys than girls, and sick singleton was more than twins. In the early group, the incidence was 52.1% for neonatal asphyxia, 22.5% for feeding intolerance, 14.8% for intracranial hemorrhage, 6.3% for scleredema, 24.7% for neonatal hyperbilirubinemia, 24.6% for hypoglycemia, 1.1% for apnea, and 3.2% for respiratory distress syndrome. Infants develop differently at different stages of corrected gestational age. The incidence of low body weight (6%) after correction for 3 months was significantly reduced compared with correction for gestational age, and the difference was statistically significant ( P  < 0.05). The nutrient absorption of infants younger than gestational age can promote physical catch-up growth, physical development, and neurodevelopment. Therefore, the physical growth of infants younger than gestational age requires supplementation that focuses on nutrition.

scholarly journals PENGARUH FASILITATOR PENDAMPING DAN KELEMBAGAAN TERHADAP TINGKAT KINERJA KEUANGAN DENGAN PENGAWASAN PEMERINTAH DAERAH SEBAGAI VARIABEL MEDIASI

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Ayumilawarty Ayumilawarty ◽  
Arifuddin Mas'ud ◽  
Husin Husin
Keyword(s):  
Local Government ◽  
Financial Performance ◽  
Financial Management ◽  
Survey Method ◽  
Regional Government ◽  
Entire Study ◽  
Unit Management ◽  
Study Population ◽  
Relationship Of ◽  
The Relationship

This study aims to find out and analyze the influence of facilitator and institutional facilitators on the level of financial performance with the supervision of local government as a mediating variable. This study is an expo facto research using the survey method. The population in this study was 64 respondents from Kelurahan Unit Management in Kendari City. The sample of this study is the entire study population which amounted to 64 financial management units.The results of the study show that the facilitator has a positive and significant effect on financial performance. The facilitator has a negative and insignificant effect on the supervision of the local government, the institution has a positive and not significant effect on financial performance, the institution has a positive and significant effect on the supervision of the local government and supervision of the regional government positive and significant effect on financial performance. Regional government oversight is not able to act as a mediating variable on the relationship of facilitating facilitators in improving financial performance and supervision of local government capable of acting as a mediating variable on the relationship of facilitating facilitators in improving financial performance.

scholarly journals HUBUNGAN PERCAYA DIRI DENGAN HASIL BELAJAR PKn PESERTA DIDIK KELAS V SDN-4 PAHANDUT PALANGKA RAYA

2017 ◽  
Vol 16 (2) ◽  
pp. 138-143
Author(s):  
Misyanto Misyanto
Keyword(s):  
Data Analysis ◽  
Learning Outcomes ◽  
Correlation Method ◽  
Class V ◽  
Entire Study ◽  
Significance Level ◽  
School Year ◽  
Study Population ◽  
Relationship Of ◽  
The Relationship

This study aims to determine the relationship of confidence with the results of learning Civics students Class V SDN-4 Pahandut Even Semester Year Lesson 2016/2017. The population in this study is all students of class V in SDN-4 Pahandut in the 2016/2017 school year, amounting to 45 people. The sample of this study is the entire study population (population research). Instruments in this study are questionnaires and tests. The method used in this research is correlation method and the analysis used is Product Moment Correlation formula. Conclusion that there is a relationship Confident with Learning Outcomes Civics Students Class V SDN-4 Pahandut Palangka Raya Lesson 2012/2013. It is based on the results of data analysis is r arithmetic> r table = 0.797> 0.248 (at 5% significance level).

The relationship between maternal and umbilical cord adropin levels with the presence and severity of preeclampsia

2017 ◽  
Vol 45 (7) ◽  
Author(s):  
Burcu Dincgez Cakmak ◽  
Betul Dundar ◽  
Abdullah Serdar Acikgoz ◽  
Gulten Ozgen ◽  
Tayfur Cift ◽  
...  
Keyword(s):  
Platelet Count ◽  
Birth Weight ◽  
Pregnant Women ◽  
Umbilical Cord ◽  
Gestational Age ◽  
Perinatal Outcomes ◽  
Enzyme Linked Immunosorbent Assay ◽  
Gestational Age At Delivery ◽  
Blood Pressures ◽  
The Relationship

AbstractAim:To investigate both maternal and umbilical cord adropin levels in patients with preeclampsia and the possible relations with its severity and perinatal outcomes.Materials and methods:In this study, a total of 38 preeclamptic and 40 age-matched healthy pregnant women between January and June 2016 were included. Serum and cord adropin levels were measured using an enzyme-linked immunosorbent assay (ELISA).Results:The maternal and umbilical cord adropin levels were significantly lower in the preeclamptic group compared to controls [71.19±22.21 vs. 100.76±27.02 ng/L and 92.39 (59.77:129.89) vs. 106.20 (74.42:208.02) ng/L, P<0.001, respectively]. While maternal adropin levels were significantly lower in the severe preeclampsia group as compared to the mild preeclamptic group [66.45 (21.49:98.02) vs. 76.17 (58.06:109.58), P=0.007], umbilical cord adropin levels did not differ between each group [91.32 (59.77:113.34) vs. 92.87 (63.12:129.89), P=0.750]. Maternal adropin level was negatively correlated with systolic and diastolic blood pressures (r=−0.60, P<0.001 and r=−0.58, P<0.001, respectively) and positively correlated with platelet count (r=0.27, P=0.016). Moreover, umbilical cord adropin levels were weakly correlated with gestational age at delivery (r=0.28, P=0.012) and birth weight (r=0.28, P=0.014).Conclusion:The present study is the first to demonstrate a significant association between maternal and umbilical adropin levels and the presence and severity of preeclampsia. Adropin might be a useful parameter for predicting the presence and severity of preeclampsia.

scholarly journals An evaluation of the potential to improve perinatal outcomes by improving antenatal detection of small for gestational age babies in Scotland: a retrospective population cohort study

2020 ◽  
Vol 5 ◽  
pp. 35 ◽  
Author(s):  
Claire M. Austin ◽  
Michael Dias ◽  
Jane E. Norman ◽  
Corinne Love ◽  
Rachael Wood ◽  
...  
Keyword(s):  
Perinatal Mortality ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Perinatal Outcomes ◽  
Outcome Data ◽  
Child Growth ◽  
Perinatal Deaths ◽  
Growth Standards ◽  
Gestational Age At Delivery ◽  
Antenatal Detection

Background: Small for gestational age (SGA) babies are at high risk of perinatal mortality. We aimed to determine the potential to reduce perinatal mortality by improving antenatal detection of SGA babies in Scotland. Methods: We conducted a retrospective population study of all singleton SGA babies born in the 15 Consultant-led maternity units in Scotland in a 3-month period (1st Dec 2014 to 28th Feb 2015 inclusive).  Demographic and pregnancy outcome data were extracted from Scottish birth records for all pregnancies; case note review was performed for all SGA cases [defined as birthweight less than the 10th centile for their gestational age at delivery as defined by the appropriate sex-specific UK-WHO Child Growth Standards]. Results: The SGA rate in Scotland was 5.5% (673/12218; 95% confidence interval [CI] 5.1, 5.9) and 27.6% (186/673; 95% CI 24.3, 31.2) of SGA cases were identified prior to delivery. SGA was associated with 18.2% (12/66; 95% CI [10.1%, 30.0%) of all perinatal deaths. The majority (10/12, 83.3%) of SGA babies who died had been identified as SGA in the antenatal period. There was no difference in perinatal mortality whether SGA was detected or not (5.4% [10/186; 95% CI 2.8, 10.0] in the SGA detected group vs 0.4% [2/487 [95% CI 0.3, 2.2] in the non-detected group after adjusting for risk factors for SGA, gestation at delivery and birthweight centile (Adjusted odds ratio [AOR] 0.85 [95% CI 0.5, 1.5], p=0.556). Conclusions: Despite only around a quarter of SGA babies being identified antenatally, the potential to reduce perinatal mortality in the Scottish population by improving SGA detection is limited. Only a minority of perinatal deaths occurred in SGA babies; and in the majority of these SGA was detected antenatally.

scholarly journals Prediction of distance visual acuity in presbyopic astigmatic subjects

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rie Hoshikawa ◽  
Kazutaka Kamiya ◽  
Fusako Fujimura ◽  
Nobuyuki Shoji
Keyword(s):  
Visual Acuity ◽  
Spherical Equivalent ◽  
Prediction Formula ◽  
Entire Study ◽  
Distance Visual Acuity ◽  
Regression Formula ◽  
Study Population ◽  
Matched Comparison ◽  
Relationship Of ◽  
The Relationship

AbstractThis study was aimed to determine the effect of the amount of astigmatism on distance visual acuity, and to provide a prediction formula of visual acuity according to astigmatism, in a presbyopic population. We comprised 318 eyes of 318 consecutive patients (158 phakic and 160 pseudophakic subjects) without any eye diseases, except for refractive errors with astigmatism of 3 diopter or less. We assessed the relationship of the spherical equivalent visual acuity (SEVA) with astigmatism, and also provided a regression formula of visual acuity according to astigmatism in such subjects. We found a significant correlation between the SEVA and the amount of astigmatism (r = 0.715, p < 0.001) in the entire study population. We obtained similar results, not only in phakic eyes (r = 0.718, p < 0.001), but also in pseudophakic eyes (r = 0.717, p < 0.001). The regression formula was expressed as follows: y = 0.017x2 + 0.125x − 0.116 (R2 = 0.544), where y = logMAR SEVA, and x = astigmatism. We also found no significant differences in the SEVA for matched comparison among the with-the-rule (WTR), against-the-rule (ATR), and oblique (OBL) astigmatism subgroups (p = 0.922). These regression formulas may be clinically beneficial not only for estimating the visual prognosis after astigmatic correction, but also for determining the surgical indication of astigmatic correction.

Usia Resiko Tinggi dan Perdarahan Post Partum

2018 ◽  
Vol 3 (2) ◽  
pp. 91
Author(s):  
Ani Media Harumi ◽  
Kasiati Kasiati
Keyword(s):  
High Risk ◽  
Post Partum ◽  
Chi Square ◽  
Sample Number ◽  
Chi Square Test ◽  
Study Population ◽  
Relationship Of ◽  
The Relationship

Abstract: The purpose of this study is to analyze the relationship of age high risk with the incidence ofbleeding post partum in dr. M. Soewandhie Surabaya hospital. This research is analytic with an approachof a sectional cross. The study population was all post partum mothers in the Dr. M. Soewandhie Surabayahospital in January 2016 to March 2017, which amounts to an average of 1840respondents while theresearch sample number 182. Measuring collection sheet data obtained by systematic random sampling.The Study was conducted Chi-Square test obtained mean count X2 (0,00) is less than á (0.05) thenH0 is rejected and H1 accepted it means that there is a relationship between the age of high risk withbleeding post partum. Conclusion, there is a relationship between the age of high risk with the incidenceof bleeding post partum in the Spaceof the Maternity room Dr. Moch. Soewandhie Surabayahospital.

Perinatal outcomes in women affected by different types of headache disorders: A prospective cohort study

Cephalalgia ◽  
2021 ◽  
pp. 033310242110292
Author(s):  
Isabella Neri ◽  
Daniela Menichini ◽  
Francesca Monari ◽  
Ludovica Spanò Bascio ◽  
Federico Banchelli ◽  
...  
Keyword(s):  
Migraine With Aura ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Migraine Without Aura ◽  
Perinatal Outcomes ◽  
First Trimester ◽  
Tension Type Headache ◽  
Headache Disorders ◽  
Aneuploidy Screening ◽  
Type Headache

Objective This study aims to investigate pregnancy and perinatal outcomes in women with tension-type headache, migraine without aura and migraine with aura by comparing them to women without any headache disorders. Study design Prospective cohort study including singleton pregnancies attending the first trimester aneuploidy screening at the University Hospital of Modena, in Northern Italy, between June 2018 and December 2019. Results A total of 515 consecutive women were included and headache disorders were reported in 43.5% of them (224/515). Tension-type headache was diagnosed in 24.3% of the cases, while 14% suffered from migraine without aura and 5.2% from migraine with aura. Birthweight was significantly lower in women affected by migraine with aura respective to other groups, and a significantly higher rate of small for gestational age infants was found in tension-type headache (10.4%) and in migraine with aura (24.9%) groups respective to the others (p < 0.001). Moreover, the admission to the neonatal intensive care unit was significantly higher in all the headache groups (p = 0.012). Multivariate analysis showed that women presenting tension-type headache (OR 4.19, p = 0.004), migraine with aura (OR 5.37, p = 0.02), a uterine artery pulsatility index >90th centile (OR 3.66, p = 0.01), low multiple of the median (MoM) of Pregnancy-associated plasma protein-A (PAPP-A) (OR 0.48, p = 0.05) and high MoM of Inhibin-A (OR 3.24, p = 0.03) at first trimester, are independently associated with the delivery of small for gestational age infants when compared to women without headache disorders. Conclusion Migraine with aura and tension type headache expose women to an increased risk of delivering small for gestational age infants, in association with some utero-placenta markers evaluated at first trimester. These women with headache disorders have an additional indication to undergo first trimester aneuploidy screening and would possibly benefit from specific interventions.

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