The effect of maternal age on cardiac adaptation in pregnancy

Author(s):  
H. Z. Ling ◽  
P. Garcia Jara ◽  
K. H. Nicolaides ◽  
N. A. Kametas
2018 ◽  
Vol 35 (3-4) ◽  
pp. 94-100
Author(s):  
S. M. Salendu W. ◽  
Sutomo Raharjo ◽  
Immanuel Mustadjab ◽  
Nan Warouw

The risk factors of low birthweight infants were assessed in a retrospective study covering 3607 singleton livebirth infants at Manado Hospital from January until December 1993. The analysis confirmed that patterns of risk birthweight hypertension in pregnancy (P<0.01), maternal education (P<0.01), maternal age (P<0.05), and parity (P<0.01), marital status (P<0.01), history of abortion (P<0.05), and parity (P<0.01). Anemia in pregnancy was also associated with birthweight in low birth weight (P<0.05). Asymetric intrauterine growth retardation (Ponderal Index below 2.32) was found both in premature and term infants.


2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Ning Wang ◽  
Ying-Ming Zheng ◽  
Lei Li ◽  
Fan Jin

Aneuploidy in pregnancy is known to increase with advanced maternal age (AMA) and associate with repeated implantation failure (RIF), and repeated miscarriage (RM). Preimplantation genetic screening (PGS) has been introduced into clinical practice, screening, and eliminating aneuploidy embryos, which can improve the chance of conceptions for infertility cases with poor prognosis. These patients are a good target group to assess the possible benefit of aneuploidy screening. Although practiced widely throughout the world, there still exist some doubts about the efficacy of this technique. Recent randomized trials were not as desirable as we expected, suggesting that PGS needs to be reconsidered. The aim of this review is to discuss the efficacy of PGS.


2015 ◽  
Vol 4 (2) ◽  
pp. 104 ◽  
Author(s):  
Yi Li ◽  
Qi-Fei Liu ◽  
Dan Zhang ◽  
Ying Shen ◽  
Kui Ye ◽  
...  

2013 ◽  
Vol 3 (4) ◽  
pp. 159-164 ◽  
Author(s):  
Alessandro Favilli ◽  
Silvia Pericoli ◽  
Gian Carlo Di Renzo ◽  
Sandro Gerli

1997 ◽  
Vol 15 (3-4) ◽  
pp. 287-302 ◽  
Author(s):  
Julia C. Berryman ◽  
Kate C. Windridge
Keyword(s):  

2020 ◽  
pp. 66-68
Author(s):  
Sangeeta Sangeeta ◽  
Kalpana Mehta ◽  
Vimla Choudhary ◽  
Vinod Vinod ◽  
Anusha Anusha

BACKGROUND Pregnancy is affected by maternal age from conception till delivery. Various studies have been conducted globally to study this effect; few in developing countries. It is associated with decreased fertility and increased risk. Simultaneously higher advanced technique and better supported maternal and neonatal care also exist. Maternal age is increasing in developing countries as well, so we have conducted this study. METHOD: It is observational prospective analytic study, conducted in umaid hospital , Dr S N medical college ,jodhpur. Total 322 patients were included in study, fulfilling inclusion criteria over period of 6 months. RESULT : A total no. of 322 elderly pregnant patients were selected for the study. Most of the cases were in the age group 35 to 39 years (89.93%). Multi gravida (71.8%) and grand multi para (22.22%) constituted the largest group. Most of the cases belong to lower socio-economic status (90%). Percentage of unbooked cases was 82.98%. The causes of delay in pregnancy were preference for male child (25.1%) and unawareness of contraception (22.36%). The incidence of diabetes mellitus and chronic hypertension were increased. Overall caesarean rate was increased (35.4%). Incidence of abortions 21(6.5%), preterm delivery 18(5.6%), oligohydramnios 20(6.21%), APH 9(2.8%) and PROM 16(4.96%), low birth weight baby 33(10.25%), NICU admission 18 (5.6%), IUGR 14(4.34%) all were high. The preference for male child 81(25.1%) and lack of awareness 72(22.36%) were two major reason for continuing pregnancies and deliveries till late age. CONCLUSION The present study showed that pregnancy at advanced age is a higher risk pregnancy in term of increased maternal and perinatal morbidity and mortality.


2022 ◽  
Vol 17 (1) ◽  
Author(s):  
Kimberly Page ◽  
Cristina Murray-Krezan ◽  
Lawrence Leeman ◽  
Mary Carmody ◽  
Julia M. Stephen ◽  
...  

Abstract Background A quarter of pregnant women use alcohol, 6.5/1000 deliveries are affected by opioid use disorder (OUD), and the prevalence of cannabis use in pregnant women is increasing. However, marijuana co-exposure in polysubstance-using women is not well described. Methods The well-characterized ENRICH-1 cohort (n = 251), which focused on the effects of two primary exposures of interest—opioids and alcohol, was used to (1) estimate the prevalence/frequency of marijuana use in those with OUD and/or alcohol use, and (2) examined correlates of marijuana use. Participants were classified into an OUD group (n = 125), Alcohol group (n = 69), and concurrent OUD and Alcohol (OUD + Alcohol) group (n = 57). Self-report and biomarkers ascertained substance use. Multivariable logistic regression identified correlates of marijuana use. Results The prevalence of any marijuana use in pregnancy was 43.2%, 52.6%, and 46.4% in the OUD, OUD + Alcohol, and Alcohol groups, respectively. Correspondingly, weekly or daily use was reported by 19.4%, 21.0%, and 24.6% of participants. In the OUD and OUD + Alcohol groups, the proportion of women using marijuana was significantly higher in those taking buprenorphine (45.8% and 58.3%, respectively) compared to women using methadone (37.5% and 42.9%, respectively). Mean maternal age was lower in women who used marijuana in all three groups compared to non-marijuana users. Independent correlates of marijuana use (controlling for group, race/ethnicity, education, and smoking) were maternal age (adjusted Odds Ratio (aOR) per 5-year increment 0.61; (95% CI 0.47, 0.79)), and polysubstance use (aOR 2.02; 95% CI 1.11, 3.67). There was a significant interaction between partnership status and group: among women who were not in a partnership, those in the OUD and OUD + Alcohol groups had lower odds of marijuana use relative to the Alcohol group. For women in the Alcohol group, partnered women had lower odds of marijuana use than un-partnered women (aOR 0.12; 95% CI: 0.02, 0.68). Conclusions Results indicate a relatively high prevalence and frequency of marijuana use in pregnant women being treated for OUD and/or women consuming alcohol while pregnant. These results highlight the need for ongoing risk reduction strategies addressing marijuana use for pregnant women receiving OUD treatment and those with alcohol exposure.


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